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Department of Biomedical Engineering
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CRISPR/Cas9-mediated mutagenesis to validate the synergy between PARP1 inhibition and chemotherapy in -mutated breast cancer cells.
Bioengineering & translational medicine Jan, 2020 | Pubmed ID: 31989039
Point-of-care detection, characterization, and removal of chocolate bloom using a handheld Raman spectrometer.
Scientific reports Jun, 2020 | Pubmed ID: 32555247
Emulating Early Atherosclerosis in a Vascular Microphysiological System Using Branched Tissue-Engineered Blood Vessels.
Advanced biology Apr, 2021 | Pubmed ID: 33852179
Therapeutic Nanocarriers Inhibit Chemotherapy-Induced Breast Cancer Metastasis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Nov, 2022 | Pubmed ID: 36220339
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens.
Nature genetics Jan, 2023 | Pubmed ID: 36624340
Focused ultrasound-mediated brain genome editing.
Research square Jan, 2023 | Pubmed ID: 36712096
Proceedings of the National Academy of Sciences of the United States of America Aug, 2023 | Pubmed ID: 37579143
Modeling and countering the effects of cosmic radiation using bioengineered human tissues.
Biomaterials Oct, 2023 | Pubmed ID: 37633022
Enabling continuous immune cell recirculation on a microfluidic array to study immunotherapeutic interactions in a recapitulated tumour microenvironment.
Lab on a chip Jan, 2024 | Pubmed ID: 38180130
Human vascular organoids with a mosaic mutation recapitulate Proteus syndrome.
bioRxiv : the preprint server for biology Jan, 2024 | Pubmed ID: 38328122
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs.
Nature biotechnology Mar, 2024 | Pubmed ID: 38514799
Chronic Opioid Treatment Arrests Neurodevelopment and Alters Synaptic Activity in Human Midbrain Organoids.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jun, 2024 | Pubmed ID: 38549185
Encoding spatial tumour dynamics with Starfysh.
Nature reviews. Cancer Oct, 2024 | Pubmed ID: 39394485
Columbia University
Cong Xu*,1,
Siyu He*,1,
Yuefei Zhu1,
Gazelle Crasto2,
Caroline Chen1,
Morgan L. Clay3,
Yeh-Hsing Lao3,
Kam W. Leong1
1Department of Biomedical Engineering, Columbia University,
2College of Dental Medicine, Division of Periodontics, Columbia University,
3Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York
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