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Department of Biochemistry
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Mutations in the 16S rRNA genes of Helicobacter pylori mediate resistance to tetracycline.
Journal of bacteriology Apr, 2002 | Pubmed ID: 11914344
The tetracycline resistance protein Tet(o) perturbs the conformation of the ribosomal decoding centre.
Molecular microbiology Sep, 2002 | Pubmed ID: 12354218
Mechanism of Tet(O)-mediated tetracycline resistance.
The EMBO journal Feb, 2003 | Pubmed ID: 12574130
Rapid, high-yield expression and purification of Ca2+-ATPase regulatory proteins for high-resolution structural studies.
Protein expression and purification Mar, 2005 | Pubmed ID: 15721779
The effects of mutation on the regulatory properties of phospholamban in co-reconstituted membranes.
Biochemistry Mar, 2005 | Pubmed ID: 15736939
Rational design of peptide inhibitors of the sarcoplasmic reticulum calcium pump.
Biochemistry Jul, 2006 | Pubmed ID: 16834336
The molecular basis for cyclopiazonic acid inhibition of the sarcoplasmic reticulum calcium pump.
The Journal of biological chemistry Mar, 2007 | Pubmed ID: 17259168
Peptide inhibitors use two related mechanisms to alter the apparent calcium affinity of the sarcoplasmic reticulum calcium pump.
Biochemistry Sep, 2008 | Pubmed ID: 18702513
Effects of phospholamban transmembrane mutants on the calcium affinity, maximal activity, and cooperativity of the sarcoplasmic reticulum calcium pump.
Biochemistry Oct, 2009 | Pubmed ID: 19708671
Phosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pump.
Journal of molecular biology Jan, 2011 | Pubmed ID: 21108950
Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy.
The Journal of biological chemistry May, 2012 | Pubmed ID: 22427649
Transmembrane helix 11 is a genuine regulator of the endoplasmic reticulum Ca2+ pump and acts as a functional parallel of β-subunit on α-Na+,K+-ATPase.
The Journal of biological chemistry Jun, 2012 | Pubmed ID: 22528494
Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A.
The Journal of biological chemistry Aug, 2012 | Pubmed ID: 22707725
Phospholamban C-terminal residues are critical determinants of the structure and function of the calcium ATPase regulatory complex.
The Journal of biological chemistry Sep, 2014 | Pubmed ID: 25074938
Deception in simplicity: hereditary phospholamban mutations in dilated cardiomyopathy.
Biochemistry and cell biology = Biochimie et biologie cellulaire Feb, 2015 | Pubmed ID: 25563649
Regulation of the sarcoplasmic reticulum calcium pump by divergent phospholamban isoforms in zebrafish.
The Journal of biological chemistry Mar, 2015 | Pubmed ID: 25593315
University of Alberta
Graeden Winkelaar1,
Catharine Trieber1,
Jitendra Kumar1,
Michael Overduin1
1Department of Biochemistry, University of Alberta
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