Joseph C. Wu

A PET study of the pathophysiology of negative symptoms in schizophrenia. Positron emission tomography.

Optical imaging of cardiac reporter gene expression in living rats.

Positron emission tomography imaging of cardiac reporter gene expression in living rats.

Positron-emission tomography reporter gene expression imaging in rat myocardium.

Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography.

Brightening depression.

Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery.

Molecular imaging of cardiovascular gene products.

Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter.

Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium.

Common congenital heart disorders in adults.

Chronotherapeutics (light and wake therapy) in affective disorders.

Human gene therapy and imaging: cardiology.

Image-guided cardiac cell delivery using high-resolution small-animal ultrasound.

Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.

Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation.

Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene.

In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery.

18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer.

Molecular imaging of cardiac stem cell transplantation.

Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival.

In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium.

Frontal lobe metabolic decreases with sleep deprivation not totally reversed by recovery sleep.

Overview of stem cells and imaging modalities for cardiovascular diseases.

Right coronary cameral fistula resulting from surgery of double chamber right ventricle.

Clinical dilemmas in treating left ventricular thrombus.

Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells.

Molecular imaging of human embryonic stem cells: keeping an eye on differentiation, tumorigenicity and immunogenicity.

Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging.

Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.

Integration of genomics, proteomics, and imaging for cardiac stem cell therapy.

Positron emission tomography imaging of conditional gene activation in the heart.

An unusual cause of stroke from a left atrial mass.

Cardiovascular molecular imaging.

Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium.

Surgically palliated double-inlet left ventricle with transposition of the great arteries mistaken for aortic aneurysm with dissection.

Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease.

Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation.

Quantum dot imaging for embryonic stem cells.

Sleep deprivation PET correlations of Hamilton symptom improvement ratings with changes in relative glucose metabolism in patients with depression.

Comparison of imaging techniques for tracking cardiac stem cell therapy.

Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function.

In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival.

Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects.

Reporter gene imaging following percutaneous delivery in swine moving toward clinical applications.

Imaging of VEGF receptor in a rat myocardial infarction model using PET.

Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration.

In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation.

A novel platform device for rodent echocardiography.

Can radionuclide imaging predict future response to stem cell therapy?

Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation.

Intracellular and extracellular targets of molecular imaging in the myocardium.

Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential.

Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality.

Seeing is believing: tracking cells to determine the effects of cell transplantation.

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts.

Comparison of different adult stem cell types for treatment of myocardial ischemia.

Short hairpin RNA interference therapy for ischemic heart disease.

Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes.

Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.

Molecular imaging: antidote to cardiac stem cell controversy.

Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation.

Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases.

[Molecular imaging for stem cell myocardial regeneration].

Cardiac differentiation of embryonic stem cells with point-source electrical stimulation.

MicroRNA profiling of human-induced pluripotent stem cells.

Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart.

Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation.

Imaging survival and function of transplanted cardiac resident stem cells.

Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder.

Imaging gene expression in human mesenchymal stem cells: from small to large animals.

Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery.

Molecular imaging of human embryonic stem cells.

Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain.

Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging.

Comparison of gene-transfer efficiency in human embryonic stem cells.

Effects of cell number on teratoma formation by human embryonic stem cells.

Long term non-invasive imaging of embryonic stem cells using reporter genes.

Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate.

Novel minicircle vector for gene therapy in murine myocardial infarction.

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.

nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis.

Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium.

Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells.

Multimodality cardiovascular molecular imaging, part I.

Multimodality cardiovascular molecular imaging, Part II.

Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction.

Modeling conduction in host-graft interactions between stem cell grafts and cardiomyocytes.

Antioxidants improve early survival of cardiomyoblasts after transplantation to the myocardium.

Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction.

Hemodynamic forces regulate embryonic stem cell commitment to vascular progenitors.

Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury.

Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells.

A nonviral minicircle vector for deriving human iPS cells.

Human iPS cell-based therapy: considerations before clinical applications.

Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion.

Rosiglitazone increases myocardial glucose metabolism in insulin-resistant cardiomyopathy.

CRY2 is associated with depression.

Current perspectives on imaging cardiac stem cell therapy.

Advances in cardiovascular molecular imaging for tracking stem cell therapy.

Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead.

Effects of ionizing radiation on self-renewal and pluripotency of human embryonic stem cells.

The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.

Effects of long-term culture on human embryonic stem cell aging.

Micro-CT for characterization of murine CV disease models.

Current-Controlled Electrical Point-Source Stimulation of Embryonic Stem Cells.

Inducible expression of stem cell associated intermediate filament nestin reveals an important role in glioblastoma carcinogenesis.

Embryonic stem cell biology: insights from molecular imaging.

Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499.

Elastic properties of induced pluripotent stem cells.

Methods to assess stem cell lineage, fate and function.

MicroRNA-210 as a novel therapy for treatment of ischemic heart disease.

Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging.

Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function.

Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells.

Sex differences in the diagnostic evaluation of coronary artery disease.

Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation.

Molecular imaging of RNA interference therapy targeting PHD2 for treatment of myocardial ischemia.

Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors.

Enhanced healing of diabetic wounds by topical administration of adipose tissue-derived stromal cells overexpressing stromal-derived factor-1: biodistribution and engraftment analysis by bioluminescent imaging.

Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells.

Cardiovascular molecular imaging: focus on clinical translation.

Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells.

Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation.

Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells.

Radiation exposure from imaging tests: is there an increased cancer risk?

Comparison of human induced pluripotent and embryonic stem cells: fraternal or identical twins?

Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid.

Derivation of human induced pluripotent stem cells for cardiovascular disease modeling.

Imaging cardiac stem cell therapy: translations to human clinical studies.

Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging.

Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation.

Imaging of embryonic stem cell migration in vivo.

Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells.

In vivo bioluminescence for tracking cell fate and function.

Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells.

Ex vivo acidic preconditioning enhances bone marrow ckit+ cell therapeutic potential via increased CXCR4 expression.

Differences in osteogenic differentiation of adipose-derived stromal cells from murine, canine, and human sources in vitro and in vivo.

Imaging atherosclerosis with F18-fluorodeoxyglucose positron emission tomography: What are we actually seeing?

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells.

Brain SPECT Imaging in Complex Psychiatric Cases: An Evidence-Based, Underutilized Tool.

Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA.

Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation.

Double knockdown of prolyl hydroxylase and factor-inhibiting hypoxia-inducible factor with nonviral minicircle gene therapy enhances stem cell mobilization and angiogenesis after myocardial infarction.

Enhancement of human adipose-derived stromal cell angiogenesis through knockdown of a BMP-2 inhibitor.

Imaging: guiding the clinical translation of cardiac stem cell therapy.

Nonintegrating knockdown and customized scaffold design enhances human adipose-derived stem cells in skeletal repair.

In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium.

Endothelial progenitor cells in cardiovascular disease and chronic inflammation: from biomarker to therapeutic agent.

Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes.

Role of molecular imaging in stem cell therapy for myocardial restoration.

Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?

Large Animal Induced Pluripotent Stem Cells as Pre-Clinical Models For Studying Human Disease.

Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming.

Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in ɛ4 carriers.

Imaging Stem Cell Therapy for the Treatment of Peripheral Arterial Disease.

Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease.

Induced Pluripotent Stem Cells as a Disease Modeling and Drug Screening Platform.

Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure.

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns.

CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma.

Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity.

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding.

Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging.

The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles.

Atomic force mechanobiology of pluripotent stem cell-derived cardiomyocytes.

Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation.

Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.

In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake.

Multimodality imaging evaluation of functional and clinical benefits of percutaneous coronary intervention in patients with chronic total occlusion lesion.

Safe genetic modification of cardiac stem cells using a site-specific integration technique.

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.

Sacrificial layer technique for axial force post assay of immature cardiomyocytes.

MicroRNA expression profiling of human-induced pluripotent and embryonic stem cells.

Transient, inducible, placenta-specific gene expression in mice.

Pushing the reset button: chemical-induced conversion of amniotic fluid stem cells into a pluripotent state.

Biomaterial applications in cardiovascular tissue repair and regeneration.

Imaging neural stem cell graft-induced structural repair in stroke.

Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.

Human embryonic stem cell-derived endothelial cells as cellular delivery vehicles for treatment of metastatic breast cancer.

Effective delivery of stem cells using an extracellular matrix patch results in increased cell survival and proliferation and reduced scarring in skin wound healing.

mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.

Returns of the living dead: therapeutic action of irradiated and mitotically inactivated embryonic stem cells.

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2012) e-Century Publishing Corporation.

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.

In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.

A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards.

Pluripotent stem cells: immune to the immune system?

Advances in nanotechnology for the management of coronary artery disease.

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells.

Immunogenicity of pluripotent stem cells and their derivatives.

Dissecting the molecular relationship among various cardiogenic progenitor cells.

The Right Heart in Congenital Heart Disease, Mechanisms and Recent Advances.

Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42).

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.

Molecular imaging: the key to advancing cardiac stem cell therapy.

The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells.

Stem cell isolation: Differential stickiness.

Induced pluripotency of human prostatic epithelial cells.

Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases.

Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions.

Global epigenomic reconfiguration during mammalian brain development.

Development of Poly(β-amino ester)-Based Biodegradable Nanoparticles for Nonviral Delivery of Minicircle DNA.

Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells.

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies.

Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia.

Cortical bone-derived stem cells: a novel class of cells for myocardial protection.

A transgenic tri-modality reporter mouse.

Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.

Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy.

Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation.

Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia.

Patient-specific stem cells and cardiovascular drug discovery.

Predicting the future with stem cells.

Imaging cardiac stem cell transplantation using radionuclide labeling techniques: clinical applications and future directions.

American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2014) e-Century Publishing Corporation.

Cardiac stem cell biology: glimpse of the past, present, and future.

Cardiovascular molecular imaging as a tool to study biology.

Relationship between echocardiographic and magnetic resonance derived measures of right ventricular size and function in patients with pulmonary hypertension.

Tracking gene and cell fate for therapeutic gain.

The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function.

Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening.

Construction and validation of nano gold tripods for molecular imaging of living subjects.

Human-induced pluripotent stem cell models of inherited cardiomyopathies.

Stem cells and cardiovascular drug development--reply.

Modeling inherited cardiac disorders.

Stem cell imaging: from bench to bedside.

Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions.

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.

Human stem cells for modeling heart disease and for drug discovery.

Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.

Chemically defined generation of human cardiomyocytes.

Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus b3-induced myocarditis and antiviral drug screening platform.

The effects of levosimendan on renal function early after heart transplantation: results from a pilot randomized trial.

A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targets.

Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts.

Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells.

Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing.

Effects of Transendocardial CD34+ Cell Transplantation in Patients With Ischemic Cardiomyopathy.

Cross Talk of Combined Gene and Cell Therapy in Ischemic Heart Disease: Role of Exosomal MicroRNA Transfer.

Cardiac tissue slice transplantation as a model to assess tissue-engineered graft thickness, survival, and function.

On-line visualization of ischemic burden during repetitive ischemia/reperfusion.

Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system.

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.

[Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction.

Variable activation of the DNA damage response pathways in patients undergoing single-photon emission computed tomography myocardial perfusion imaging.

Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes.

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

Cardiovascular molecular imaging: Expanding the paradigms and parameters.

MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells.

Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.

Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.

RNAseq Reveals a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.

Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment.

Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes.

Exosomes as potential alternatives to stem cell therapy in mediating cardiac regeneration.

Human induced pluripotent stem cell-derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes.

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

Hurdles to clinical translation of human induced pluripotent stem cells.

Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers.

Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model.

Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells.

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model.

Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction.

Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells.

Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine.

Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas.

Stem cell reprogramming: A 3D boost.

Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs.

Induced pluripotent stem cells: at the heart of cardiovascular precision medicine.

Human-induced pluripotent stem cell approaches to model inborn and acquired metabolic heart diseases.

Efficacy of CD34+ Stem Cell Therapy in Nonischemic Dilated Cardiomyopathy Is Absent in Patients With Diabetes but Preserved in Patients With Insulin Resistance.

Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial-to-Mesenchymal Transition.

Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.

Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group.

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.

Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine.

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging.

Distilling complexity to advance cardiac tissue engineering.

Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.

Finding Expandable Induced Cardiovascular Progenitor Cells.

Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-α (HIF1-α) in an Ovine Model of Acute Myocardial Infarction.

Effects of cellular origin on differentiation of human induced pluripotent stem cell-derived endothelial cells.

Alternative approaches to generating cardiomyocytes are under development.

Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.

Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review.

Challenging the complementarity of different metrics of left atrial function: insight from a cardiomyopathy-based study.

iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy.

Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans.

Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity.

Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy.

Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome.

Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro.

Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers.

Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

Cardiac subtype characterization using all-optical action potential imaging.

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring.

A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases.

Genome Editing in Cardiovascular Biology.

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons.

Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue.

Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness.

3-Dimensionally Printed, Native-Like Scaffolds for Myocardial Tissue Engineering.

Specific Imaging of Bacterial Infection Using 6″-F-Fluoromaltotriose: A Second-Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria.

Global position paper on cardiovascular regenerative medicine.

Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas.

Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy.

Autoantibody profiling on a plasmonic nano-gold chip for the early detection of hypertensive heart disease.

Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs.

Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

21st Century Cardio-Oncology: Identifying Cardiac Safety Signals in the Era of Personalized Medicine.

Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.

Combining hiPSCs and Human Genetics: Major Applications in Drug Development.

Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.

Multiscale technologies for treatment of ischemic cardiomyopathy.

Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy.

Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems.

Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells.

Towards Cardio-Precision medicine.

Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs.

GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement.

Cardiac Cell Cycle Activation as a Strategy to Improve iPSC-Derived Cardiomyocyte Therapy.

Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine.

Simply derived epicardial cells.

Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease.

Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?

Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction.

Mining Exosomal MicroRNAs from Human-Induced Pluripotent Stem Cells-Derived Cardiomyocytes for Cardiac Regeneration.

Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis.

Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo.

SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation.

Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond.

Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles.

Applications of genetically engineered human pluripotent stem cell reporters in cardiac stem cell biology.

Dyslipidaemia: In vivo genome editing of ANGPTL3: a therapy for atherosclerosis?

Truncating Variants in NAA15 Are Associated with Variable Levels of Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies.

Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation.

Omics, Big Data, and Precision Medicine in Cardiovascular Sciences.

Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation.

Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study.

Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptides from a collagen matrix.

Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm.

Effects of Repetitive Transendocardial CD34 Cell Transplantation in Patients With Nonischemic Dilated Cardiomyopathy.

Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models.

Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells.

Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists.

Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells.

Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come?

Telomere shortening is a hallmark of genetic cardiomyopathies.

Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid.

Cytokines profile of reverse cardiac remodeling following transcatheter aortic valve replacement.

Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods.

From the BCVS Chair.

Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity.

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis.

Big bottlenecks in cardiovascular tissue engineering.

A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.

Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure.

Myocardial viability of the peri-infarct region measured by T1 mapping post manganese-enhanced MRI correlates with LV dysfunction.

Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell.

Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development.

Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer.

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.

Complex heritability in cardiomyopathy.

Harnessing cell pluripotency for cardiovascular regenerative medicine.

Stanford Cardiovascular Institute.

The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment.

Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes.

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.

Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development.

Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells.

A Combination of Itraconazole and Amiodarone Is Highly Effective against Infection of Human Stem Cell-Derived Cardiomyocytes.

Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources.

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution.

Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis.

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.

Clinical Trial in a Dish: Personalized Stem Cell-Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT-Prolonging Drugs.

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.

Induced pluripotent stem cells as a novel cancer vaccine.

Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies.

Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities.

Improving the engraftment and integration of cell transplantation for cardiac regeneration.

Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms.

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function.

Electronic Cigarettes: Where There Is Smoke There Is Disease.

Total Microfluidic chip for Multiplexed diagnostics (ToMMx).

Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes From Children With DCMA, a Mitochondrial Cardiomyopathy.

RNA Sequencing Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Congenital Heart Disease Patients.

Therapeutic genome editing in cardiovascular diseases.

Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo.

Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload-Induced Heart Failure.

Gut microbiota and cardiovascular disease: opportunities and challenges.

Single-cell RNA sequencing in cardiovascular development, disease and medicine.

Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI.

Molecular Signatures of Beneficial Class Effects of Statins on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Levitating Cells to Sort the Fit and the Fat.

Human-induced pluripotent stem cells for modelling metabolic perturbations and impaired bioenergetics underlying cardiomyopathies.

Molecular Imaging of Infective Endocarditis With 6''-[F]Fluoromaltotriose Positron Emission Tomography-Computed Tomography.

High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human iPSCs for Multi-omics Analysis.

Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes.

Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells.

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.

Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy.

Tumor Repressor Circular RNA as a New Target for Preventative Gene Therapy Against Doxorubicin-Induced Cardiotoxicity.

An extracellular matrix paradox in myocardial scar formation.

A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants.

Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank.

Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue.

Single-cell protein expression of hiPSC-derived cardiomyocytes using Single-Cell Westerns.

Immune biomarkers link air pollution exposure to blood pressure in adolescents.

Primer on Biomarker Discovery in Cardio-Oncology: Application of Omics Technologies.

Author Correction: Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI.

Atlas of Exosomal microRNAs Secreted From Human iPSC-Derived Cardiac Cell Types.

Effects of Cryopreservation on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Assessing Drug Safety Response Profiles.

Clinical Trial in a Dish: Using Patient-Derived Induced Pluripotent Stem Cells to Identify Risks of Drug-Induced Cardiotoxicity.

CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes.

Air pollution exposure is linked with methylation of immunoregulatory genes, altered immune cell profiles, and increased blood pressure in children.

Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes.

Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy.

Human-induced pluripotent stem cells in cardiovascular research: current approaches in cardiac differentiation, maturation strategies, and scalable production.

ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension.

Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations.

Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies.

Reconstructing the heart using iPSCs: Engineering strategies and applications.

Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes.

Human induced pluripotent stem cell-derived atrial cardiomyocytes carrying an SCN5A mutation identify nitric oxide signaling as a mediator of atrial fibrillation.

Generation of three heterozygous KCNH2 mutation-carrying human induced pluripotent stem cell lines for modeling LQT2 syndrome.

Macrophages: Potential Therapeutic Target of Myocardial Injury in COVID-19.

Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction.

CRISPRi/a Screening with Human iPSCs.

Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYH7 mutations.

Generation of three induced pluripotent stem cell lines (SCVIi014-A, SCVIi015-A, and SCVIi016-A) from patients with LQT1 caused by heterozygous mutations in the KCNQ1 gene.

Highlights from Stanford Drug Discovery Symposium 2021.

Leaders in Cardiovascular Research: Joseph C. Wu.

Deciphering pathogenicity of variants of uncertain significance with CRISPR-edited iPSCs.

Adverse effects of air pollution-derived fine particulate matter on cardiovascular homeostasis and disease.

Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy.

Protocol to measure contraction, calcium, and action potential in human-induced pluripotent stem cell-derived cardiomyocytes.

Basic and Translational Research in Cardiac Repair and Regeneration: JACC State-of-the-Art Review.

Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying TNNI3 mutations.

Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations.

An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.

Cardiac reprogramming via chromatin remodeling by CRISPR activation.

Preoperative Computed Tomography Angiography Reveals Leaflet-Specific Calcification and Excursion Patterns in Aortic Stenosis.

Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells.

Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant.

Heterozygous LMNA mutation-carrying iPSC lines from three cardiac laminopathy patients.

The use of new CRISPR tools in cardiovascular research and medicine.

Vein to artery: the first arteriogenesis in the mammalian embryo.

Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy.

Deconvoluting the Cells of the Human Heart with iPSC Technology: Cell Types, Protocols, and Uses.

Ferroptosis of Pacemaker Cells in COVID-19.

Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons.

Progress in multicellular human cardiac organoids for clinical applications.

Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants.

Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.

Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.

Generation of Embryonic Origin-Specific Vascular Smooth Muscle Cells from Human Induced Pluripotent Stem Cells.

Intersectionality and genetic ancestry: New methods to solve old problems.

High-Throughput Analysis of Drug Safety Responses in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using Multielectrode Array.

Cellular and Engineered Organoids for Cardiovascular Models.

HMOX1 Genetic Polymorphisms Display Ancestral Diversity and May Be Linked to Hypertensive Disorders in Pregnancy.

Generation of two induced pluripotent stem cell lines carrying the phospholamban R14del mutation for modeling ARVD/C.

Modeling Susceptibility to Cardiotoxicity in Cancer Therapy Using Human iPSC-Derived Cardiac Cells and Systems Biology.

Cardio- and Neurotoxicity of Selected Anti-COVID-19 Drugs.

A pilot clinical trial of cell therapy in heart failure with preserved ejection fraction.

Shifting machine learning for healthcare from development to deployment and from models to data.

Human induced pluripotent stem cells for studying mitochondrial diseases in the heart.

Generation of human induced pluripotent stem cell lines carrying heterozygous PLN mutation from dilated cardiomyopathy patients.

Contractility and Calcium Transient Maturation in the Human iPSC-Derived Cardiac Microfibers.