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Chapter 1

General Pharmacological Principles

Découverte de médicaments : aperçu
Découverte de médicaments : aperçu
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for ...
Développement préclinique : aperçu
Développement préclinique : aperçu
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. ...
Essais cliniques : aperçu
Essais cliniques : aperçu
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific ...
Nomenclature des médicaments
Nomenclature des médicaments
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United ...
Réglementation des médicaments
Réglementation des médicaments
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. ...
Classes et catégories de médicaments
Classes et catégories de médicaments
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that ...
Liaisons médicament-récepteur
Liaisons médicament-récepteur
Drug-receptor bonds are formed through various chemical forces when drugs interact with target cells. Covalent bonds, strong and irreversible, are ...
Interactions médicament-récepteur
Interactions médicament-récepteur
Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. ...
Voies d’administration des médicaments : aperçu
Voies d’administration des médicaments : aperçu
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical. Enteral administration refers ...
Voies d’administration du médicament : entérale
Voies d’administration du médicament : entérale
Medications can be administered through the enteral route using liquids, capsules, or tablets. Enteral administration involves drug administration via the ...
Voies d’administration du médicament : Parentérale
Voies d’administration du médicament : Parentérale
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability ...
Autres voies d’administration des médicaments
Autres voies d’administration des médicaments
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent ...
Médicaments sur ordonnance, en vente libre et orphelins
Médicaments sur ordonnance, en vente libre et orphelins
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including ...
Facteurs influant sur la réponse aux médicaments : aperçu
Facteurs influant sur la réponse aux médicaments : aperçu
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily ...
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