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Chapter 2

Adverse Drug Effects and Chemical Toxicity

Pharmacovigilance
Pharmacovigilance
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug ...
Toxicomanie
Toxicomanie
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting ...
Effets des produits chimiques : aperçu
Effets des produits chimiques : aperçu
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in ...
Types de toxines
Types de toxines
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or ...
Réactions toxiques : aperçu
Réactions toxiques : aperçu
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive ...
Réactions allergiques aux médicaments
Réactions allergiques aux médicaments
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic ...
Tératogénicité
Tératogénicité
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and ...
Mutagénicité et cancérogénicité
Mutagénicité et cancérogénicité
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for ...
Antidotes
Antidotes
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely ...
Prévention de l’absorption ultérieure de poison
Prévention de l’absorption ultérieure de poison
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using ...
Élimination améliorée du poison
Élimination améliorée du poison
Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures. Antidotes serve a crucial role in ...
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