Performing the DNA Fiber Assay and Image Acquisition
10:33
Results: Analysis of Variation in DNA Replication Dynamics in the Presence of Nanoparticles
12:04
Conclusion
Transcription
DNA fiber analysis allows us to understand how nanomaterials impact DNA at single-molecular level. And this information will enable developing strategies that will reduce nanotoxicity. This technique allows us to understand DNA dynamics and how it
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The methodology assists in the analysis of variation in DNA replication dynamics in the presence of nanoparticles. Different methodologies can be adopted based on the cytotoxicity level of the material of interest. In addition, a description of the image analysis is provided to help in DNA fiber analysis.