Yale Stem Cell Center,
Department of Genetics,
Yale Stem Cell Center, Department of Genetics
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Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12087098
PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.
Current biology : CB Dec, 2003 | Pubmed ID: 14653992
IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients.
The Journal of cell biology Dec, 2003 | Pubmed ID: 14662739
Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.
Experimental cell research Sep, 2005 | Pubmed ID: 15963500
Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation.
The Journal of biological chemistry Sep, 2005 | Pubmed ID: 16043480
A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.
The Journal of biological chemistry Mar, 2006 | Pubmed ID: 16407298
In vitro generation of germ cells from murine embryonic stem cells.
Nature protocols , 2006 | Pubmed ID: 17487192
Debugging cellular reprogramming.
Nature cell biology Aug, 2007 | Pubmed ID: 17671453
Reprogramming of human somatic cells to pluripotency with defined factors.
Nature Jan, 2008 | Pubmed ID: 18157115
Generation of human-induced pluripotent stem cells.
Nature protocols , 2008 | Pubmed ID: 18600223
Disease-specific induced pluripotent stem cells.
Cell Sep, 2008 | Pubmed ID: 18691744
Regulatory networks define phenotypic classes of human stem cell lines.
Nature Sep, 2008 | Pubmed ID: 18724358
Human iPS cell derivation/reprogramming.
Current protocols in stem cell biology Jan, 2009 | Pubmed ID: 19170021
Generation of induced pluripotent stem cells from human blood.
Blood May, 2009 | Pubmed ID: 19299331
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.
Nature biotechnology Apr, 2009 | Pubmed ID: 19329998
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming.
Nature biotechnology Apr, 2009 | Pubmed ID: 19330000
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.
Nature Jun, 2009 | Pubmed ID: 19458618
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.
Cell stem cell Jul, 2009 | Pubmed ID: 19540188
A role for Lin28 in primordial germ-cell development and germ-cell malignancy.
Nature Aug, 2009 | Pubmed ID: 19578360
Cardiomyocyte differentiation of human induced pluripotent stem cells.
Circulation Oct, 2009 | Pubmed ID: 19786631
Hematopoietic development from human induced pluripotent stem cells.
Annals of the New York Academy of Sciences Sep, 2009 | Pubmed ID: 19796250
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells.
Nature biotechnology Nov, 2009 | Pubmed ID: 19826408
Generation of functional human hepatic endoderm from human induced pluripotent stem cells.
Hepatology (Baltimore, Md.) Jan, 2010 | Pubmed ID: 19877180
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts.
Nature genetics Dec, 2009 | Pubmed ID: 19881528
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.
PLoS genetics Nov, 2009 | Pubmed ID: 19911041
Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells.
Blood Apr, 2010 | Pubmed ID: 20065292
DYS-HAC-iPS cells: the combination of gene and cell therapy to treat duchenne muscular dystrophy.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2010 | Pubmed ID: 20125163
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients.
Nature Mar, 2010 | Pubmed ID: 20164838
Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity.
Stem cell reviews Jun, 2010 | Pubmed ID: 20376579
Reprogramming of T cells from human peripheral blood.
Cell stem cell Jul, 2010 | Pubmed ID: 20621044
Research highlights.
Regenerative medicine Jul, 2010 | Pubmed ID: 20632853
Five classic articles in somatic cell reprogramming.
The Yale journal of biology and medicine Sep, 2010 | Pubmed ID: 20885901
Human pluripotent stem cells produce natural killer cells that mediate anti-HIV-1 activity by utilizing diverse cellular mechanisms.
Journal of virology Jan, 2011 | Pubmed ID: 20962093
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome).
Blood Jan, 2011 | Pubmed ID: 21037085
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.
Nature genetics Dec, 2010 | Pubmed ID: 21057500
MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states.
Cell stem cell Dec, 2010 | Pubmed ID: 21112562
Analysis of differential proteomes of induced pluripotent stem cells by protein-based reprogramming of fibroblasts.
Journal of proteome research Mar, 2011 | Pubmed ID: 21175196
Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies.
The Journal of allergy and clinical immunology Jun, 2011 | Pubmed ID: 21185069
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.
Development (Cambridge, England) Mar, 2011 | Pubmed ID: 21270052
Induced pluripotent stem cells for neural tissue engineering.
Biomaterials Aug, 2011 | Pubmed ID: 21514663
Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.
PloS one , 2011 | Pubmed ID: 21559507
Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients.
Annals of neurology Sep, 2011 | Pubmed ID: 21721033
Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21807996
Research highlights.
Regenerative medicine Nov, 2011 | Pubmed ID: 22050520
Cell cycle adaptations of embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22084091
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.
Nature biotechnology Dec, 2011 | Pubmed ID: 22119741
The lesser known story of X chromosome reactivation: a closer look into the reprogramming of the inactive X chromosome.
Cell cycle (Georgetown, Tex.) Jan, 2012 | Pubmed ID: 22234239
Human induced pluripotent stem cells and neurodegenerative disease: prospects for novel therapies.
Current opinion in neurology Apr, 2012 | Pubmed ID: 22357218
Humanized murine model for HBV and HCV using human induced pluripotent stem cells.
Archives of pharmacal research Feb, 2012 | Pubmed ID: 22370780
Overcoming Reprogramming Resistance of Fanconi Anemia Cells.
Blood Feb, 2012 | Pubmed ID: 22371882
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2012 | Pubmed ID: 22451909
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