Lincai Ye

Department of Thoracic and Cardiovascular Surgery,
Shanghai Children’s Hospital,
School of Medicine,
Institute of Pediatric Translational Medicine,
Shanghai Children’s Medical Center,
Shanghai Institute for Pediatric Congenital Heart Disease,
Department of Thoracic and Cardiovascular Surgery, Shanghai Children’s Hospital, School of Medicine,
Institute of Pediatric Translational Medicine, Shanghai Children’s Medical Center, School of Medicine,
Shanghai Institute for Pediatric Congenital Heart Disease, Shanghai Children’s Medical Center, School of Medicine

Shanghai Jiaotong University

BIOGRAPHY

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PUBLICATIONS

Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients.

Journal of proteomics Jun, 2013 | Pubmed ID: 23571024

Postsurgical comparison of pulsatile hemodynamics in five unique total cavopulmonary connections: identifying ideal connection strategies.

The Annals of thoracic surgery Oct, 2013 | Pubmed ID: 23910632

Hypoxia-induced cytosolic calcium influx is mediated primarily by the reverse mode of Na+/Ca2+ exchanger in smooth muscle cells of fetal small pulmonary arteries.

The journal of obstetrics and gynaecology research Jun, 2014 | Pubmed ID: 24888919

Elevated NCX1 and NCKX4 expression in the patent postnatal ductus arteriosus of ductal-dependent congenital heart disease patients.

Pediatric cardiology Apr, 2015 | Pubmed ID: 25500693

Long noncoding RNA HOTAIR, a hypoxia-inducible factor-1α activated driver of malignancy, enhances hypoxic cancer cell proliferation, migration, and invasion in non-small cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Dec, 2015 | Pubmed ID: 26088446

Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects.

PloS one , 2015 | Pubmed ID: 26426694

Over-expression of HSPA12B protects mice against myocardium ischemic/reperfusion injury through a PPARγ-dependent PI3K/Akt/eNOS pathway.

American journal of translational research , 2015 | Pubmed ID: 26885270

Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation.

Scientific reports Mar, 2016 | Pubmed ID: 26976548

A gain-of-function ACTC1 3'UTR mutation that introduces a miR-139-5p target site may be associated with a dominant familial atrial septal defect.

Scientific reports May, 2016 | Pubmed ID: 27139165

GSK-3β Inhibitor CHIR-99021 Promotes Proliferation Through Upregulating β-Catenin in Neonatal Atrial Human Cardiomyocytes.

Journal of cardiovascular pharmacology Dec, 2016 | Pubmed ID: 27575008

Age-Dependent Oxidative DNA Damage Does Not Correlate with Reduced Proliferation of Cardiomyocytes in Humans.

PloS one , 2017 | Pubmed ID: 28099512

Geranylgeranylacetone attenuates myocardium ischemic/reperfusion injury through HSP70 and Akt/GSK-3β/eNOS pathway.

American journal of translational research , 2017 | Pubmed ID: 28337268

A neonatal rat model of increased right ventricular afterload by pulmonary artery banding.

The Journal of thoracic and cardiovascular surgery Nov, 2017 | Pubmed ID: 28697895

The Role of Na+/Ca2+ Exchanger 1 in Maintaining Ductus Arteriosus Patency.

Scientific reports Aug, 2017 | Pubmed ID: 28852106

Hypoxia-induced ARHGAP26 deficiency inhibits the proliferation and migration of human ductus arteriosus smooth muscle cell through activating RhoA-ROCK-PTEN pathway.

Journal of cellular biochemistry Jun, 2019 | Pubmed ID: 30592323

Effects of hypoxia on cardiomyocyte proliferation and association with stage of development.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Oct, 2019 | Pubmed ID: 31545287

Pressure Overload Greatly Promotes Neonatal Right Ventricular Cardiomyocyte Proliferation: A New Model for the Study of Heart Regeneration.

Journal of the American Heart Association Jun, 2020 | Pubmed ID: 32475201

Role of Blood Oxygen Saturation During Post-Natal Human Cardiomyocyte Cell Cycle Activities.

JACC. Basic to translational science May, 2020 | Pubmed ID: 32478207

Dexmedetomidine Protects Human Cardiomyocytes Against Ischemia-Reperfusion Injury Through α2-Adrenergic Receptor/AMPK-Dependent Autophagy.

Frontiers in pharmacology , 2021 | Pubmed ID: 34093174

Downregulated developmental processes in the postnatal right ventricle under the influence of a volume overload.

Cell death discovery Aug, 2021 | Pubmed ID: 34365468

Metabolic maturation during postnatal right ventricular development switches to heart-contraction regulation due to volume overload.

Journal of cardiology Jan, 2022 | Pubmed ID: 34518077

GATA4 Regulates Developing Endocardium Through Interaction With ETS1.

Circulation research Nov, 2022 | Pubmed ID: 36263775

Potential Roles of miRNAs in Acute Rejection for Vascularized Composite Allotransplantation.

Journal of inflammation research , 2022 | Pubmed ID: 36330168

Expression and Predictive Functional Profiles of MicroRNAs Data in Vascularized Composite Allotransplantation Acute Rejection.

Frontiers in bioscience (Landmark edition) Sep, 2022 | Pubmed ID: 36336858

Impaired cell-cell communication and axon guidance because of pulmonary hypoperfusion during postnatal alveolar development.

Respiratory research Jan, 2023 | Pubmed ID: 36631871

The implication of chromosomal abnormalities in the surgical outcomes of Chinese pediatric patients with congenital heart disease.

Frontiers in cardiovascular medicine , 2023 | Pubmed ID: 37293289

INSTITUTIONS

Shanghai Jiaotong University

JOVE ARTICLES

Establishment and Confirmation of a Postnatal Right Ventricular Volume Overload Mouse Model

Sijuan Sun^*,1,

Hongbin Zhu^*,2,

Shoubao Wang³,

Xiuxia Xu⁴,

Lincai Ye^2,5,6

¹Department of Pediatric Intensive Care Unit, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University,

²Department of Thoracic and Cardiovascular Surgery, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiaotong University,

³Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University,

⁴Department of Radiology, Huangpu Branch, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine,

⁵Institute of Pediatric Translational Medicine, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University,

⁶Shanghai Institute for Pediatric Congenital Heart Disease, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University

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