Hematology and Cell Therapy Area
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In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer.
Scientific reports Oct, 2017 | Pubmed ID: 29084986
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II).
Journal of translational medicine Jul, 2018 | Pubmed ID: 30064455
Allogeneic Mesenchymal Stem Cells and Biomaterials: The Perfect Match for Cardiac Repair?
International journal of molecular sciences Oct, 2018 | Pubmed ID: 30347686
Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and as a potential tumor suppressor gene that is epigenetically regulated.
Haematologica Aug, 2019 | Pubmed ID: 30655376
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.
Nature communications Feb, 2019 | Pubmed ID: 30778059
Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.
Nature medicine Jul, 2019 | Pubmed ID: 31270502
DNA Methylation of Enhancer Elements in Myeloid Neoplasms: Think Outside the Promoters?
Cancers Sep, 2019 | Pubmed ID: 31554341
Generation of an induced pluripotent stem cell line (CIMAi001-A) from a compound heterozygous Primary Hyperoxaluria Type I (PH1) patient carrying p.G170R and p.R122* mutations in the AGXT gene.
Stem cell research Dec, 2019 | Pubmed ID: 31715429
Phase II multicenter randomized controlled clinical trial on the efficacy of intra-articular injection of autologous bone marrow mesenchymal stem cells with platelet rich plasma for the treatment of knee osteoarthritis.
Journal of translational medicine Sep, 2020 | Pubmed ID: 32948200
Delivery of cardiovascular progenitors with biomimetic microcarriers reduces adverse ventricular remodeling in a rat model of chronic myocardial infarction.
Acta biomaterialia May, 2021 | Pubmed ID: 33716175
Isolation methods of large and small extracellular vesicles derived from cardiovascular progenitors: A comparative study.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Jan, 2022 | Pubmed ID: 34968647
G9a inhibition by CM-272: Developing a novel anti-tumoral strategy for castration-resistant prostate cancer using 2D and 3D in vitro models.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Jun, 2022 | Pubmed ID: 35483199
The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes.
Nature communications Dec, 2022 | Pubmed ID: 36494342
Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures.
Stem cell reports Jan, 2023 | Pubmed ID: 36563688
Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia.
Haematologica Oct, 2023 | Pubmed ID: 37021532
Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction.
Computers in biology and medicine Mar, 2024 | Pubmed ID: 38335818
Single-cell transcriptional profile of CD34+ hematopoietic progenitor cells from del(5q) myelodysplastic syndromes and impact of lenalidomide.
Nature communications Jun, 2024 | Pubmed ID: 38902243
Epigenetic-based differentiation therapy for Acute Myeloid Leukemia.
Nature communications Jul, 2024 | Pubmed ID: 38956053
BET inhibitors downregulate the expression of the essential lncRNA in multiple myeloma through regulation of the transcription factor FLI1.
Haematologica Feb, 2025 | Pubmed ID: 39323408
An automated network-based tool to search for metabolic vulnerabilities in cancer.
Nature communications Oct, 2024 | Pubmed ID: 39394196
Andrea Sánchez-Bueno1,
Olalla Iglesias-García1,
Pilar Montero-Calle1,
Juan José Gavira2,
Felipe Prosper3,4,5,
Manuel M. Mazo1,3
1Biomedical Engineering Program, Enabling Technologies Division, CIMA Universidad de Navarra, and Instituto de Investigación Sanitaria de Navarra (IdiSNA),
2Department of Cardiology, Clínica Universidad de Navarra and Instituto de Investigación Sanitaria de Navarra (IdiSNA),
3Hematology and Cell Therapy Area, Clínica Universidad de Navarra and Instituto de Investigación Sanitaria de Navarra (IdiSNA),
4, Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) CB16/12/00489,
5Hemato-Oncology Program, Cancer Division, CIMA Universidad de Navarra
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