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Chapter 3

Protein Structure

מהם חלבונים?
מהם חלבונים?
Overview Proteins are chains of amino acids that are connected by peptide bonds and folded into a 3-dimensional structure. The side chains of individual ...
ארגון חלבונים
ארגון חלבונים
Overview Proteins are one of the fundamental building blocks of life that carry out many diverse functions in the cell. Proteins are assembled from amino ...
קיפול חלבונים
קיפול חלבונים
Overview Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation which ...
שימור תחומי חלבונים על פני חלבונים שונים
שימור תחומי חלבונים על פני חלבונים שונים
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally ...
חלבונים כדוריים וסיביים
חלבונים כדוריים וסיביים
Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities. Globular ...
חלבונים לא מסודרים במהותם
חלבונים לא מסודרים במהותם
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows ...
הרכבת קומפלקס חלבונים
הרכבת קומפלקס חלבונים
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes ...
חלבונים מצומדים
חלבונים מצומדים
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with ...
עמילואיד פיברילס
עמילואיד פיברילס
Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or ...
מבנה נוגדנים
מבנה נוגדנים
Overview Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced ...
משפחות חלבונים
משפחות חלבונים
Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein ...
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