A New Method for Inducing a Depression-Like Behavior in RatsVladimir Zeldetz *1, Dmitry Natanel *2, Matthew Boyko 2, Alexander Zlotnik 2, Honore N. Shiyntum 3, Julia Grinshpun 2, Dmitry Frank 2, Ruslan Kuts 2, Evgeni Brotfain 2, Jochanan Peiser 2
1Department of Emergent Medicine, Soroka University Medical Center, Ben-Gurion University of the Negev, 2Division of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 3Department of Biophysics and Biochemistry, Oles' Honchar Dnipro National University
This protocol describes a new model by which healthy rats could contract depression over a given time periodthrough contagion by exposure to chronic unpredictable stressed (CUS) rats.