Cincinnati Children Hospital Medical Center (CCHMC)

2 ARTICLES PUBLISHED IN JoVE

Medicine

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Kan N. Hor¹, Rolf Baumann², Gianni Pedrizzetti³, Gianni Tonti³, William M. Gottliebson¹, Michael Taylor¹, D. Woodrow Benson¹, Wojciech Mazur⁴

¹The Heart Institute, Cincinnati Children Hospital Medical Center (CCHMC), ²TomTec, Imaging Systems GmbH, ³AMID, Advanced Medical Imaging Development SRL, ⁴The Heart and Vascular Center, The Christ Hospital

An accurate and practical method to measure parameters like strain in myocardial tissue is of great clinical value, since it has been shown, that strain is a more sensitive and earlier marker for contractile dysfunction than the frequently used parameter EF.

Immunology and Infection

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance

Michael Taylor¹, Tuhina Banerjee¹, Neyda VanBennekom¹, Ken Teter¹

¹Department of Molecular Biology and Microbiology, University of Central Florida

In this report, we describe how surface plasmon resonance is used to detect toxin entry into the host cytosol. This highly sensitive method can provide quantitative data on the amount of cytosolic toxin, and it can be applied to a range of toxins.