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Heidelberg University Children's Hospital

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

Leukocyte Infiltration of Cremaster Muscle in Mice Assessed by Intravital Microscopy
Simon Alexander Kranig *1, Trim Lajqi *1, Raphaela Tschada 1, Maylis Braun 1, Navina Kuss 1, Johannes Pöschl 1, Hannes Hudalla 1
1Department of Neonatology, Heidelberg University Children's Hospital

Here, we show how to perform intravital microscopy on post-capillary venules of the mouse cremaster muscle. Commonly applied to different models of inflammation and sepsis, particularly those induced by chemokines and cytokines, we highlight its relevance in the study of muscolopathies involving exaggerated muscular leukocyte infiltration.

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