UNSW Sydney

1 ARTICLES PUBLISHED IN JoVE

Medicine

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents

Sarah-Jane Leigh^*1, Michael D. Kendig^*1, Margaret J. Morris¹

¹Department of Pharmacology, School of Medical Sciences, UNSW Sydney

This protocol describes the use of a highly palatable, western-style cafeteria diet to model overeating and obesity in rodents. Here, we provide a detailed outline of food selection, preparation and measurement, and explain methodological factors that assist in generating a robust and reproducible phenotype.