Coleen Murphy

Regulation of aging and age-related disease by DAF-16 and heat-shock factor.

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.

Comparing genomic expression patterns across species identifies shared transcriptional profile in aging.

Enrichment of regulatory motifs upstream of predicted DAF-16 targets.

The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.

The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling.

Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.

Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.

Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.

Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.

TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.

Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.

The role of insulin/IGF-like signaling in C. elegans longevity and aging.

Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.

TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.

Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms.

Aging: miRacles of longevity?

EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan.

The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.