Ashutosh Mishra

T cell epitope "hotspots" on the HIV Type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry.

The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19.

Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo.

Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome.

Sgt1 dimerization is negatively regulated by protein kinase CK2-mediated phosphorylation at Ser361.

Bub1-mediated adaptation of the spindle checkpoint.

PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.

Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity.

Identification and characterization of phosphorylation sites within the pregnane X receptor protein.

Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy.

Quantitative protein analysis by mass spectrometry.

PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death.

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.

Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.

ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.

Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease.

High-Throughput Profiling of Proteome and Posttranslational Modifications by 16-Plex TMT Labeling and Mass Spectrometry.