Department of Medicine,
Department of Immunology and Pathology,
Department of Developmental Biology
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Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development.
Development (Cambridge, England) Jan, 2006 | Pubmed ID: 16308329
FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate.
Developmental biology Feb, 2007 | Pubmed ID: 17014841
Rebuilding the coronary vasculature: hedgehog as a new candidate for pharmacologic revascularization.
Trends in cardiovascular medicine Apr, 2007 | Pubmed ID: 17418368
FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.
Developmental biology Jul, 2007 | Pubmed ID: 17544391
FGF9 and SHH regulate mesenchymal Vegfa expression and development of the pulmonary capillary network.
Development (Cambridge, England) Oct, 2007 | Pubmed ID: 17881491
Fibroblast growth factors and Hedgehogs: at the heart of the epicardial signaling center.
Trends in genetics : TIG Jan, 2008 | Pubmed ID: 18054407
The Dynamic Role of Cardiac Macrophages in Aging and Disease.
Current cardiology reports May, 2022 | Pubmed ID: 35595950
Novel tool to suppress cell proliferation in vivo demonstrates that myocardial and coronary vascular growth represent distinct developmental programs.
Developmental dynamics : an official publication of the American Association of Anatomists Mar, 2008 | Pubmed ID: 18297725
Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice.
The Journal of clinical investigation Jul, 2008 | Pubmed ID: 18568073
Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development.
Development (Cambridge, England) Sep, 2008 | Pubmed ID: 18725519
Shared circuitry: developmental signaling cascades regulate both embryonic and adult coronary vasculature.
Circulation research Jan, 2009 | Pubmed ID: 19179669
Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators.
Circulation Jan, 2010 | Pubmed ID: 20065164
The development of myocardial fibrosis in transgenic mice with targeted overexpression of tumor necrosis factor requires mast cell-fibroblast interactions.
Circulation Nov, 2011 | Pubmed ID: 22025605
Coronary collaterals predict improved survival and allograft function in patients with coronary allograft vasculopathy.
Circulation. Heart failure Jul, 2013 | Pubmed ID: 23709657
Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart.
Journal of the American Heart Association Sep, 2013 | Pubmed ID: 24080909
Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy.
PloS one , 2013 | Pubmed ID: 24349409
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.
Immunity Jan, 2014 | Pubmed ID: 24439267
Origin and functions of tissue macrophages.
Immunity Jul, 2014 | Pubmed ID: 25035951
Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2014 | Pubmed ID: 25139991
Rethinking Phase II Clinical Trial Design in Heart Failure.
Clinical investigation Jan, 2013 | Pubmed ID: 25343020
Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25349429
Necrotic myocardial cells release damage-associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo.
Journal of the American Heart Association Jun, 2015 | Pubmed ID: 26037082
Intra-Aortic Balloon Counterpulsation in Patients With Chronic Heart Failure and Cardiogenic Shock: Clinical Response and Predictors of Stabilization.
Journal of cardiac failure Nov, 2015 | Pubmed ID: 26164215
Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development.
Cell reports Jan, 2016 | Pubmed ID: 26725121
Primitive Embryonic Macrophages are Required for Coronary Development and Maturation.
Circulation research 05, 2016 | Pubmed ID: 27009605
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Circulation research Sep, 2016 | Pubmed ID: 27444755
Heart-resident CCR2 macrophages promote neutrophil extravasation through TLR9/MyD88/CXCL5 signaling.
JCI insight Aug, 2016 | Pubmed ID: 27536731
Skeletal muscle inflammation and atrophy in heart failure.
Heart failure reviews 03, 2017 | Pubmed ID: 28091823
Macrophages Facilitate Electrical Conduction in the Heart.
Cell 04, 2017 | Pubmed ID: 28431249
Pediatric and adult dilated cardiomyopathy represent distinct pathological entities.
JCI insight Jul, 2017 | Pubmed ID: 28724792
Cardiac Lymphatic Vessels, Transport, and Healing of the Infarcted Heart.
JACC. Basic to translational science 08, 2017 | Pubmed ID: 28989985
A CD103 Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis.
Immunity 11, 2017 | Pubmed ID: 29166591
Recognition of self-DNA drives cardiac inflammation: why broken hearts fail.
Nature medicine 12, 2017 | Pubmed ID: 29216037
Visualization of Monocytic Cells in Regressing Atherosclerotic Plaques by Intravital 2-Photon and Positron Emission Tomography-Based Imaging-Brief Report.
Arteriosclerosis, thrombosis, and vascular biology 05, 2018 | Pubmed ID: 29567678
Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β.
The Journal of clinical investigation Jul, 2018 | Pubmed ID: 29781811
The human heart contains distinct macrophage subsets with divergent origins and functions.
Nature medicine 08, 2018 | Pubmed ID: 29892064
Slicing Into Human Translational Cardiovascular Biology.
JACC. Basic to translational science Apr, 2016 | Pubmed ID: 30167509
The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4).
Journal of the American College of Cardiology 10, 2018 | Pubmed ID: 30360829
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.
Nature immunology 01, 2019 | Pubmed ID: 30538339
Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury.
Circulation research 01, 2019 | Pubmed ID: 30582448
Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart.
Circulation research Mar, 2019 | Pubmed ID: 30661445
Publisher Correction: Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.
Nature immunology May, 2019 | Pubmed ID: 30862954
Immunomodulatory role of non-neuronal cholinergic signaling in myocardial injury.
JCI insight Jun, 2019 | Pubmed ID: 31162139
Macrophage Plasticity and Function in the Eye and Heart.
Trends in immunology Sep, 2019 | Pubmed ID: 31422901
New Approaches to Target Inflammation in Heart Failure: Harnessing Insights from Studies of Immune Cell Diversity.
Annual review of physiology Oct, 2019 | Pubmed ID: 31658002
TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy.
JCI insight Nov, 2019 | Pubmed ID: 31672943
Targeted PET Imaging of Chemokine Receptor 2-Positive Monocytes and Macrophages in the Injured Heart.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 01, 2021 | Pubmed ID: 32444372
Chemokine Receptor 2-targeted Molecular Imaging in Pulmonary Fibrosis. A Clinical Trial.
American journal of respiratory and critical care medicine 01, 2021 | Pubmed ID: 32673071
Eosinophils Confer Protection Following Myocardial Infarction.
JACC. Basic to translational science Jul, 2020 | Pubmed ID: 32760919
Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages.
Proceedings of the National Academy of Sciences of the United States of America 08, 2020 | Pubmed ID: 32796104
A Minimal-Invasive Approach for Standardized Induction of Myocardial Infarction in Mice.
Circulation research 10, 2020 | Pubmed ID: 32854590
Beyond genomics-technological advances improving the molecular characterization and precision treatment of heart failure.
Heart failure reviews 03, 2021 | Pubmed ID: 32885327
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.
Nature immunology Oct, 2020 | Pubmed ID: 32895539
Lymphatic drainage from bronchus-associated lymphoid tissue in tolerant lung allografts promotes peripheral tolerance.
The Journal of clinical investigation 12, 2020 | Pubmed ID: 33196461
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis.
JACC. Basic to translational science Apr, 2021 | Pubmed ID: 33681537
SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.
Science translational medicine 03, 2021 | Pubmed ID: 33762433
Resident cardiac macrophages mediate adaptive myocardial remodeling.
Immunity 09, 2021 | Pubmed ID: 34320366
Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress.
Immunity 09, 2021 | Pubmed ID: 34363749
Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles.
Pediatric research Aug, 2021 | Pubmed ID: 34404929
Myocarditis after Covid-19 mRNA Vaccination.
The New England journal of medicine 09, 2021 | Pubmed ID: 34407340
Leveraging FPR2 Agonists to Resolve Inflammation and Improve Outcomes Following Myocardial Infarction.
JACC. Basic to translational science Aug, 2021 | Pubmed ID: 34466755
CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells.
Circulation 03, 2022 | Pubmed ID: 35113652
Cell specific peripheral immune responses predict survival in critical COVID-19 patients.
Nature communications 02, 2022 | Pubmed ID: 35169146
Derivation of extra-embryonic and intra-embryonic macrophage lineages from human pluripotent stem cells.
Development (Cambridge, England) Apr, 2022 | Pubmed ID: 35178561
The dynamic cardiac cellular landscape: visualization by molecular imaging.
Nature reviews. Cardiology Jun, 2022 | Pubmed ID: 35440737
Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase.
Science (New York, N.Y.) 06, 2022 | Pubmed ID: 35709278
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