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Chapter 1

General Pharmacological Principles

Scoperta di farmaci: panoramica
Scoperta di farmaci: panoramica
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for ...
Sviluppo preclinico: panoramica
Sviluppo preclinico: panoramica
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. ...
Sperimentazioni cliniche: Panoramica
Sperimentazioni cliniche: Panoramica
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific ...
Nomenclatura dei farmaci
Nomenclatura dei farmaci
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United ...
Regolamentazione dei farmaci
Regolamentazione dei farmaci
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. ...
Classi e categorie di farmaci
Classi e categorie di farmaci
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that ...
Legami farmaco-recettore
Legami farmaco-recettore
Drug-receptor bonds are formed through various chemical forces when drugs interact with target cells. Covalent bonds, strong and irreversible, are ...
Interazioni farmaco-recettore
Interazioni farmaco-recettore
Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. ...
Vie di somministrazione dei farmaci: panoramica
Vie di somministrazione dei farmaci: panoramica
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical. Enteral administration refers ...
Vie di somministrazione del farmaco: enterale
Vie di somministrazione del farmaco: enterale
Medications can be administered through the enteral route using liquids, capsules, or tablets. Enteral administration involves drug administration via the ...
Vie di somministrazione del farmaco: Parenterale
Vie di somministrazione del farmaco: Parenterale
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability ...
Vie aggiuntive di somministrazione del farmaco
Vie aggiuntive di somministrazione del farmaco
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent ...
Farmaci soggetti a prescrizione, senza prescrizione medica e farmaci orfani
Farmaci soggetti a prescrizione, senza prescrizione medica e farmaci orfani
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including ...
Fattori che influenzano la risposta ai farmaci: panoramica
Fattori che influenzano la risposta ai farmaci: panoramica
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily ...
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