Cell Targeting Evaluation and Magnetic Cell Separation
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Results: Safe and Efficient Delivery of miRNA to Endothelial Cells and Their Magnetic Responsiveness
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Conclusion
Trascrizione
The overall goal of this procedure is to introduce a technique which ensures cell modification with microRNA and in parallel cell magnetization. This method can address key challenges in the regenerative medicine field. Such as genetic engineering
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This manuscript describes the efficient, non-viral delivery of miR to endothelial cells by a PEI/MNP vector and their magnetization. Thus, in addition to genetic modification, this approach allows for magnetic cell guidance and MRI detectability. The technique can be used to improve the characteristics of therapeutic cell products.