Heddwen L. Brooks

Posttranscriptional compensation for heterozygous disruption of the kidney-specific NaK2Cl cotransporter gene.

Targeted proteomic profiling of renal Na(+) transporter and channel abundances in angiotensin II type 1a receptor knockout mice.

cDNA array identification of genes regulated in rat renal medulla in response to vasopressin infusion.

Long-term regulation of ENaC expression in kidney by angiotensin II.

Expression of osmotic stress-related genes in tissues of normal and hyposmotic rats.

Renal medullary gene expression in aquaporin-1 null mice.

Pax2 expression occurs in renal medullary epithelial cells in vivo and in cell culture, is osmoregulated, and promotes osmotic tolerance.

Altered expression of selected genes in kidney of rats with lithium-induced NDI.

Developmental expression of glucokinase in rat hypothalamus.

Comparative effects of dehydroepiandrosterone sulfate on ventricular diastolic function with young and aged female mice.

Effects of water restriction on gene expression in mouse renal medulla: identification of 3betaHSD4 as a collecting duct protein.

CARMA: A platform for analyzing microarray datasets that incorporate replicate measures.

Axial heterogeneity of vasopressin-receptor subtypes along the human and mouse collecting duct.

Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause.

Increased hexokinase II expression in the renal glomerulus of mice in response to arsenic.

Vasopressin receptor subtype 2 activation increases cell proliferation in the renal medulla of AQP1 null mice.

Involvement of the KIT/KITL signaling pathway in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in rats.

Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice.

Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.

Vasopressin increases expression of UT-A1, UT-A3, and ER chaperone GRP78 in the renal medulla of mice with a urinary concentrating defect.

Midkine, a heparin-binding protein, is increased in the diabetic mouse kidney postmenopause.

Phosphorylation of eIF2α via the general control kinase, GCN2, modulates the ability of renal medullary cells to survive high urea stress.

2012 Young Investigator Award for Excellence in Renal Physiology.

Rapamycin inhibition of mTORC1 reverses lithium-induced proliferation of renal collecting duct cells.

Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice.

2014 Robert W. Berliner Award for Excellence in Renal Physiology.