Department of Biomedical Sciences,
Regenerative Medicine Institute,
Department of Biomedical Sciences, Regenerative Medicine Institute,
Board of Governor’s Regenerative Medicine Institute,
Center for Neural Sciences in Medicine,
Samuel Oschin Comprehensive Cancer Institute
Joshua J. Breunig has not added Biography.
If you are Joshua J. Breunig and would like to personalize this page please email our Author Liaison for assistance.
Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia hypoxia.
Cerebral cortex (New York, N.Y. : 1991) Nov, 2007 | Pubmed ID: 17259645
Glowing green pyramids: a false positive for neocortical neurogenesis reveals a novel neuronal-microglial fusion in the postnatal brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2007 | Pubmed ID: 17304702
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2007 | Pubmed ID: 17360686
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.
Nature neuroscience Jul, 2007 | Pubmed ID: 17589506
Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18077357
The stumpy gene is required for mammalian ciliogenesis.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18287022
Everything that glitters isn't gold: a critical review of postnatal neural precursor analyses.
Cell stem cell Dec, 2007 | Pubmed ID: 18371403
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18728187
Decision by division: making cortical maps.
Trends in neurosciences May, 2009 | Pubmed ID: 19380167
Profiling identifies precursor suspects: notch family again!
Cell stem cell May, 2010 | Pubmed ID: 20452310
Cilia in the brain: going with the flow.
Nature neuroscience Jun, 2010 | Pubmed ID: 20498683
Failed cytokinesis of neural progenitors in citron kinase-deficient rats leads to multiciliated neurons.
Cerebral cortex (New York, N.Y. : 1991) Feb, 2011 | Pubmed ID: 20525772
Not(ch) just development: Notch signalling in the adult brain.
Nature reviews. Neuroscience May, 2011 | Pubmed ID: 21505516
Coordinating migratory neuron polarization by numb-ing communication.
Developmental cell May, 2011 | Pubmed ID: 21571215
Neural stem cells: historical perspective and future prospects.
Neuron May, 2011 | Pubmed ID: 21609820
Development and distribution of neuronal cilia in mouse neocortex.
The Journal of comparative neurology Mar, 2012 | Pubmed ID: 22020803
FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2011 | Pubmed ID: 22031906
Basic biology and mechanisms of neural ciliogenesis and the B9 family.
Molecular neurobiology Jun, 2012 | Pubmed ID: 22644387
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation.
Neural development , 2012 | Pubmed ID: 22776033
Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2013 | Pubmed ID: 23392690
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2013 | Pubmed ID: 23575824
Brain injury, neuroinflammation and Alzheimer's disease.
Frontiers in aging neuroscience , 2013 | Pubmed ID: 23874297
T-cell TGF-β signaling abrogation restricts medulloblastoma progression.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2014 | Pubmed ID: 25082897
Mutations within the pathogenic region of herpes simplex virus 1 gK signal sequences alter cell surface expression and neurovirulence.
Journal of virology Mar, 2015 | Pubmed ID: 25505072
A transposon-mediated system for flexible control of transgene expression in stem and progenitor-derived lineages.
Stem cell reports Mar, 2015 | Pubmed ID: 25702640
Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair.
Frontiers in cellular neuroscience , 2015 | Pubmed ID: 26136658
Ets Factors Regulate Neural Stem Cell Depletion and Gliogenesis in Ras Pathway Glioma.
Cell reports Jul, 2015 | Pubmed ID: 26146073
In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2016 | Pubmed ID: 26666451
Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis.
Oncotarget Feb, 2016 | Pubmed ID: 26760767
Ets Factors Regulate Neural Stem Cell Depletion and Gliogenesis in Ras Pathway Glioma.
Cell reports Dec, 2016 | Pubmed ID: 28009307
BCL6 promotes glioma and serves as a therapeutic target.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2017 | Pubmed ID: 28356518
Lethal Giant Lineage Tracing: Mutating Locally, Acting Globally.
Neuron May, 2017 | Pubmed ID: 28472645
Tetracycline-Inducible and Reversible Stable Gene Expression in Human iPSC-Derived Neural Progenitors and in the Postnatal Mouse Brain.
Current protocols in stem cell biology May, 2017 | Pubmed ID: 28510333
Organoid and Organ-On-A-Chip Systems: New Paradigms for Modeling Neurological and Gastrointestinal Disease.
Current stem cell reports , | Pubmed ID: 28983454
Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.
Cancer & metabolism , 2018 | Pubmed ID: 29692895
Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells.
Stem cell reports 06, 2018 | Pubmed ID: 29706501
In utero electroporation-based translating ribosome affinity purification identifies age-dependent mRNA expression in cortical pyramidal neurons.
Neuroscience research Jun, 2019 | Pubmed ID: 29857015
Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol.
Journal of neuroinflammation Sep, 2018 | Pubmed ID: 30201019
Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles.
Cilia , 2018 | Pubmed ID: 30410731
Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements.
Cell Sep, 2019 | Pubmed ID: 31539496
Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3.
Brain : a journal of neurology Dec, 2020 | Pubmed ID: 33141183
Generation of Murine and Human MADR Recipient Cell Lines for Locus-Specific, Stable Integration of Transgenic Elements.
STAR protocols Dec, 2020 | Pubmed ID: 33377078
Preparation, Assembly, and Transduction of Transgenic Elements Using Mosaic Analysis with Dual Recombinases (MADR).
STAR protocols Dec, 2020 | Pubmed ID: 33377093
A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma.
Cancer research Mar, 2021 | Pubmed ID: 33402390
RELA Fusion-Positive Ependymoma in a Child with Down Syndrome: A Case Report.
Pediatric neurosurgery , 2021 | Pubmed ID: 33690230
discovery of RNA proximal proteins via proximity-dependent biotinylation.
RNA biology Dec, 2021 | Pubmed ID: 34006179
Neurosurgery at the crossroads of immunology and nanotechnology. New reality in the COVID-19 pandemic.
Advanced drug delivery reviews Feb, 2022 | Pubmed ID: 34808227
Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment.
Nature communications Dec, 2021 | Pubmed ID: 34921160
SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances.
Journal of experimental & clinical cancer research : CR Jan, 2022 | Pubmed ID: 35086552
First-line Immune Checkpoint Inhibitor Combinations in Metastatic Renal Cell Carcinoma: Where Are We Going, Where Have We Been?
Drugs Mar, 2022 | Pubmed ID: 35175588
Murine-Derived Glioma Organoids and Cell Line Culture Systems.
Current protocols Feb, 2023 | Pubmed ID: 36744986
Tetracycline-Inducible and Reversible Stable Gene Expression in Human iPSC-Derived Neural Progenitors and in the Postnatal Mouse Brain.
Current protocols Jun, 2023 | Pubmed ID: 37283517
1Board of Governor’s Regenerative Medicine Institute, Cedars-Sinai Medical Center,
2Center for Neural Sciences in Medicine, Cedars-Sinai Medical Center,
3Department of Biomedical Sciences, Cedars-Sinai Medical Center,
4Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center,
5Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles
JoVEについて
Copyright © 2023 MyJoVE Corporation. All rights reserved