Wellman Center for Photomedicine Massachusetts General Hospital,
Department of Dermatology
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Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging.
Photochemistry and photobiology Jan, 2002 | Pubmed ID: 11837327
Localization of rose bengal, aluminum phthalocyanine tetrasulfonate, and chlorin e6 in the rabbit eye.
Retina (Philadelphia, Pa.) Feb, 2002 | Pubmed ID: 11884881
Photodynamic treatment has chondroprotective effects on articular cartilage.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Mar, 2002 | Pubmed ID: 11918303
Detection of female lower genital tract dysplasia using orally administered 5-aminolevulinic acid induced protoporphyrin IX: a preliminary study.
Gynecologic oncology Apr, 2002 | Pubmed ID: 11925131
Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria.
The Journal of antimicrobial chemotherapy Jun, 2002 | Pubmed ID: 12039886
Plasma matrix metalloproteinase 9 as biomarker of prostate cancer progression in Dunning (Copenhagen) rats.
The Prostate Feb, 2003 | Pubmed ID: 12518325
Photodynamic therapy with verteporfin in the radiation-induced fibrosarcoma-1 tumor causes enhanced radiation sensitivity.
Cancer research Mar, 2003 | Pubmed ID: 12615718
Targeting cells that overexpress the epidermal growth factor receptor with polyethylene glycolated BPD verteporfin photosensitizer immunoconjugates.
Photochemistry and photobiology Apr, 2003 | Pubmed ID: 12733655
Optical monitoring and treatment of potentially lethal wound infections in vivo.
The Journal of infectious diseases Jun, 2003 | Pubmed ID: 12751029
Blood flow dynamics after photodynamic therapy with verteporfin in the RIF-1 tumor.
Radiation research Oct, 2003 | Pubmed ID: 12968929
Photodynamic therapy: a new antimicrobial approach to infectious disease?
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology May, 2004 | Pubmed ID: 15122361
Targeted photodynamic therapy of established soft-tissue infections in mice.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology May, 2004 | Pubmed ID: 15122362
Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors.
Photochemistry and photobiology Apr, 2004 | Pubmed ID: 15137508
Effects of growth phase and extracellular slime on photodynamic inactivation of gram-positive pathogenic bacteria.
Antimicrobial agents and chemotherapy Jun, 2004 | Pubmed ID: 15155218
In vivo flow cytometry: a new method for enumerating circulating cancer cells.
Cancer research Aug, 2004 | Pubmed ID: 15289300
Effect of tumor host microenvironment on photodynamic therapy in a rat prostate tumor model.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2005 | Pubmed ID: 15701861
Photochemical targeting of epidermal growth factor receptor: a mechanistic study.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2005 | Pubmed ID: 15746071
Combining vascular and cellular targeting regimens enhances the efficacy of photodynamic therapy.
International journal of radiation oncology, biology, physics Mar, 2005 | Pubmed ID: 15752904
Photodynamic therapy for Staphylococcus aureus infected burn wounds in mice.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Jul, 2005 | Pubmed ID: 15986057
Synergism of epidermal growth factor receptor-targeted immunotherapy with photodynamic treatment of ovarian cancer in vivo.
Journal of the National Cancer Institute Oct, 2005 | Pubmed ID: 16234565
Liposomal delivery of photosensitising agents.
Expert opinion on drug delivery May, 2005 | Pubmed ID: 16296769
Tumor vascular permeabilization by vascular-targeting photosensitization: effects, mechanism, and therapeutic implications.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2006 | Pubmed ID: 16467106
Pretreatment photosensitizer dosimetry reduces variation in tumor response.
International journal of radiation oncology, biology, physics Mar, 2006 | Pubmed ID: 16504761
Targeting of sebocytes by aminolevulinic acid-dependent photosensitization.
Photochemistry and photobiology Mar-Apr, 2006 | Pubmed ID: 16613498
Photoinactivation of Mycobacteria in vitro and in a new murine model of localized Mycobacterium bovis BCG-induced granulomatous infection.
Antimicrobial agents and chemotherapy May, 2006 | Pubmed ID: 16641456
Targeted photodynamic therapy.
Lasers in surgery and medicine Jun, 2006 | Pubmed ID: 16671102
Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer.
Cancer research Jun, 2006 | Pubmed ID: 16740700
Protoporphyrin IX level correlates with number of mitochondria, but increase in production correlates with tumor cell size.
Photochemistry and photobiology Sep-Oct, 2006 | Pubmed ID: 16771607
Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells.
International journal of oncology Aug, 2006 | Pubmed ID: 16820882
The role of photosensitizer molecular charge and structure on the efficacy of photodynamic therapy against Leishmania parasites.
Chemistry & biology Aug, 2006 | Pubmed ID: 16931333
Vitamin D enhances ALA-induced protoporphyrin IX production and photodynamic cell death in 3-D organotypic cultures of keratinocytes.
The Journal of investigative dermatology Apr, 2007 | Pubmed ID: 17068479
A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer.
Cancer research Nov, 2006 | Pubmed ID: 17108133
Vascular and cellular targeting for photodynamic therapy.
Critical reviews in eukaryotic gene expression , 2006 | Pubmed ID: 17206921
A mechanistic study of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis.
The Journal of investigative dermatology Jun, 2007 | Pubmed ID: 17218937
Clinical manifestations and classification of Old World cutaneous leishmaniasis.
International journal of dermatology Feb, 2007 | Pubmed ID: 17269962
Tumor vascular area correlates with photosensitizer uptake: analysis of verteporfin microvascular delivery in the Dunning rat prostate tumor.
Photochemistry and photobiology Sep-Oct, 2006 | Pubmed ID: 17421078
Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus.
Photochemistry and photobiology May-Jun, 2007 | Pubmed ID: 17576383
Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells.
Experimental dermatology Aug, 2007 | Pubmed ID: 17620092
T helper type 1 cytokines and keratinocyte growth factor play a critical role in pseudoepitheliomatous hyperplasia initiation during cutaneous leishmaniasis.
Archives of dermatological research Sep, 2007 | Pubmed ID: 17643254
Peptide-induced inflammatory increase in vascular permeability improves photosensitizer delivery and intersubject photodynamic treatment efficacy.
Radiation research Sep, 2007 | Pubmed ID: 17705632
增强光动力疗法效果的的战略。
Photochemistry and photobiology Sep-Oct, 2007 | Pubmed ID: 17880492
Photodynamic therapy for cutaneous leishmaniasis: the effectiveness of topical phenothiaziniums in parasite eradication and Th1 immune response stimulation.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Oct, 2007 | Pubmed ID: 17914480
Real-time fluorescence monitoring of phenothiazinium photosensitizers and their anti-mycobacterial photodynamic activity against Mycobacterium bovis BCG in in vitro and in vivo models of localized infection.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Oct, 2007 | Pubmed ID: 17914486
Ablation of leptin signaling disrupts the establishment, development, and maintenance of endometriosis-like lesions in a murine model.
Endocrinology Feb, 2008 | Pubmed ID: 17962343
Prospects for the use of differentiation-modulating agents as adjuvant of photodynamic therapy for proliferative dermatoses.
The Journal of dermatology Apr, 2008 | Pubmed ID: 18419676
In vivo optical molecular imaging of vascular endothelial growth factor for monitoring cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2008 | Pubmed ID: 18593993
Protoporphyrin IX fluorescence photobleaching increases with the use of fractionated irradiation in the esophagus.
Journal of biomedical optics May-Jun, 2008 | Pubmed ID: 18601554
Pulsed diode laser-based monitor for singlet molecular oxygen.
Journal of biomedical optics May-Jun, 2008 | Pubmed ID: 18601555
Antimicrobial photodynamic efficacy of side-chain functionalized benzo[a]phenothiazinium dyes.
Photochemistry and photobiology Jan-Feb, 2009 | Pubmed ID: 18657053
Decreased metastatic phenotype in cells resistant to aminolevulinic acid-photodynamic therapy.
Cancer letters Nov, 2008 | Pubmed ID: 18662847
In-vivo singlet oxygen dosimetry of clinical 5-aminolevulinic acid photodynamic therapy.
Journal of biomedical optics Sep-Oct, 2008 | Pubmed ID: 19021376
Intracellular drug delivery by poly(lactic-co-glycolic acid) nanoparticles, revisited.
Molecular pharmaceutics Jan-Feb, 2009 | Pubmed ID: 19035785
Pulsed diode laser-based singlet oxygen monitor for photodynamic therapy: in vivo studies of tumor-laden rats.
Journal of biomedical optics Nov-Dec, 2008 | Pubmed ID: 19123681
Exploiting a bacterial drug-resistance mechanism: a light-activated construct for the destruction of MRSA.
Angewandte Chemie (International ed. in English) , 2009 | Pubmed ID: 19206126
Quantitative imaging of scattering changes associated with epithelial proliferation, necrosis, and fibrosis in tumors using microsampling reflectance spectroscopy.
Journal of biomedical optics Jan-Feb, 2009 | Pubmed ID: 19256692
Noninvasive measurement of aminolevulinic acid-induced protoporphyrin IX fluorescence allowing detection of murine glioma in vivo.
Journal of biomedical optics Jan-Feb, 2009 | Pubmed ID: 19256695
Diagnostic detection of diffuse glioma tumors in vive with molecular fluorescent probe-based transmission spectroscopy.
Medical physics Mar, 2009 | Pubmed ID: 19378758
Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2009 | Pubmed ID: 19447864
In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging.
Optics express May, 2009 | Pubmed ID: 19466138
Optimization of topical photodynamic therapy with 3,7-bis(di-n-butylamino)phenothiazin-5-ium bromide for cutaneous leishmaniasis.
Lasers in surgery and medicine Jul, 2009 | Pubmed ID: 19533767
Detecting epidermal growth factor receptor tumor activity in vivo during cetuximab therapy of murine gliomas.
Academic radiology Jan, 2010 | Pubmed ID: 19796971
Enhanced susceptibility to Leishmania infection in resistant mice in the absence of immediate early response gene X-1.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2009 | Pubmed ID: 19923449
Imaging tumor variation in response to photodynamic therapy in pancreatic cancer xenograft models.
International journal of radiation oncology, biology, physics Jan, 2010 | Pubmed ID: 20005458
Diffusive and directional intracellular dynamics measured by field-based dynamic light scattering.
Optics express Feb, 2010 | Pubmed ID: 20174115
Imaging and photodynamic therapy: mechanisms, monitoring, and optimization.
Chemical reviews May, 2010 | Pubmed ID: 20353192
Monitoring the efficacy of antimicrobial photodynamic therapy in a murine model of cutaneous leishmaniasis using L. major expressing GFP.
Journal of biophotonics Jun, 2010 | Pubmed ID: 20376860
System development for high frequency ultrasound-guided fluorescence quantification of skin layers.
Journal of biomedical optics Mar-Apr, 2010 | Pubmed ID: 20459273
The ABC's of industry: a postdoc program provides a sneak peek into industry careers.
Nature biotechnology Jun, 2010 | Pubmed ID: 20531344
Imaging targeted-agent binding in vivo with two probes.
Journal of biomedical optics May-Jun, 2010 | Pubmed ID: 20614996
Rapid functional definition of extended spectrum β-lactamase activity in bacterial cultures via competitive inhibition of fluorescent substrate cleavage.
Photochemistry and photobiology Nov-Dec, 2010 | Pubmed ID: 20854415
Development and applications of photo-triggered theranostic agents.
Advanced drug delivery reviews Aug, 2010 | Pubmed ID: 20858520
Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer.
Cancer research Nov, 2010 | Pubmed ID: 21045152
Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model.
Journal of biomedical optics Sep-Oct, 2010 | Pubmed ID: 21054077
Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer.
Cancer research Nov, 2010 | Pubmed ID: 21062986
Comparative split-face study of 5-aminolevulinic acid photodynamic therapy with intense pulsed light for photorejuvenation of Asian skin.
The Journal of dermatology Dec, 2010 | Pubmed ID: 21083701
Polarization-sensitive optical frequency domain imaging based on unpolarized light.
Optics express Jan, 2011 | Pubmed ID: 21263595
A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform.
Biotechnology journal Feb, 2011 | Pubmed ID: 21298805
Vaccination with photodynamic therapy-treated macrophages induces highly suppressive T-regulatory cells.
Photodermatology, photoimmunology & photomedicine Apr, 2011 | Pubmed ID: 21392113
Targeting of sebaceous glands by δ-aminolevulinic acid-based photodynamic therapy: An in vivo study.
Lasers in surgery and medicine Jul, 2011 | Pubmed ID: 21674542
Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy.
Cancer research Sep, 2011 | Pubmed ID: 21807844
High Vascular Delivery of EGF, but Low Receptor Binding Rate Is Observed in AsPC-1 Tumors as Compared to Normal Pancreas.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Aug, 2011 | Pubmed ID: 21847690
Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT.
PloS one , 2011 | Pubmed ID: 21876751
Verteporfin-based photodynamic therapy overcomes gemcitabine insensitivity in a panel of pancreatic cancer cell lines.
Lasers in surgery and medicine Sep, 2011 | Pubmed ID: 22057484
In Vivo Quantification of Tumor Receptor Binding Potential with Dual-Reporter Molecular Imaging.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Dec, 2011 | Pubmed ID: 22203241
Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells.
Cancer letters Jan, 2012 | Pubmed ID: 22266098
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