Institute of Pharmacology and Toxicology and Bio-Imaging Center/Rudolf Virchow Center,
DFG-Research Center for Experimental Biomedicine,
Institute of Pharmacology and Toxicology and Bio-Imaging Center/Rudolf Virchow Center, DFG-Research Center for Experimental Biomedicine
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Low-density lipoprotein (LDL) receptor/transferrin fusion protein: in vivo production and functional evaluation as a potential therapeutic tool for lowering plasma LDL cholesterol.
Human gene therapy Jun, 2004 | Pubmed ID: 15212712
Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.
Human molecular genetics Oct, 2005 | Pubmed ID: 16135555
Selective modulation of protein kinase A I and II reveals distinct roles in thyroid cell gene expression and growth.
Molecular endocrinology (Baltimore, Md.) Dec, 2006 | Pubmed ID: 16887886
Syndromes of hormone resistance in the hypothalamic-pituitary-thyroid axis.
Best practice & research. Clinical endocrinology & metabolism Dec, 2006 | Pubmed ID: 17161330
Technology Insight: modern methods to monitor protein-protein interactions reveal functional TSH receptor oligomerization.
Nature clinical practice. Endocrinology & metabolism Feb, 2007 | Pubmed ID: 17237844
The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation.
Molecular endocrinology (Baltimore, Md.) Mar, 2008 | Pubmed ID: 18096696
Sortilin is a putative postendocytic receptor of thyroglobulin.
Endocrinology Jan, 2009 | Pubmed ID: 18687776
A 7-year experience with low blood TSH cutoff levels for neonatal screening reveals an unsuspected frequency of congenital hypothyroidism (CH).
Clinical endocrinology Nov, 2009 | Pubmed ID: 19486019
Persistent cAMP-signals triggered by internalized G-protein-coupled receptors.
PLoS biology Aug, 2009 | Pubmed ID: 19688034
Agonist-regulated cleavage of the extracellular domain of parathyroid hormone receptor type 1.
The Journal of biological chemistry Mar, 2010 | Pubmed ID: 20080964
Genetics and phenomics of hypothyroidism due to TSH resistance.
Molecular and cellular endocrinology Jun, 2010 | Pubmed ID: 20083154
Signaling by internalized G-protein-coupled receptors.
Trends in pharmacological sciences May, 2010 | Pubmed ID: 20303186
Imaging of persistent cAMP signaling by internalized G protein-coupled receptors.
Journal of molecular endocrinology Jul, 2010 | Pubmed ID: 20378719
Real-time monitoring of somatostatin receptor-cAMP signaling in live pituitary.
Endocrinology Sep, 2010 | Pubmed ID: 20610560
FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells.
Nature protocols Apr, 2011 | Pubmed ID: 21412271
8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms.
PloS one , 2011 | Pubmed ID: 21695205
Frequent TSH receptor genetic alterations with variable signaling impairment in a large series of children with nonautoimmune isolated hyperthyrotropinemia.
The Journal of clinical endocrinology and metabolism Jan, 2012 | Pubmed ID: 22049173
Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2012 | Pubmed ID: 22291442
Disruptions of global and JAGGED1-mediated notch signaling affect thyroid morphogenesis in the zebrafish.
Endocrinology Nov, 2012 | Pubmed ID: 23008514
Dissecting signaling and functions of adhesion G protein-coupled receptors.
Annals of the New York Academy of Sciences Dec, 2012 | Pubmed ID: 23215895
Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2013 | Pubmed ID: 23267088
Cell biology: Receptor signals come in waves.
Nature Mar, 2013 | Pubmed ID: 23515157
Kinetics and mechanism of G protein-coupled receptor activation.
Current opinion in cell biology Apr, 2014 | Pubmed ID: 24530699
Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome.
The New England journal of medicine Mar, 2014 | Pubmed ID: 24571724
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