Xiaobei Zhao

In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase.

Human endonuclease VIII-like (NEIL) proteins in the giant DNA Mimivirus.

Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1.

Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE.

JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles.

The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts.

Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts.

The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.

Amyloid-β peptide is a substrate of the human 20S proteasome.

Design, synthesis and structure-activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: dual activity as cholinesterase and Aβ-aggregation inhibitors.

Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes.

Systematic clustering of transcription start site landscapes.

Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data.

GMD: measuring the distance between histograms with applications on high-throughput sequencing reads.

Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket.

Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling.

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality.

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles.

New histone supply regulates replication fork speed and PCNA unloading.

An atlas of active enhancers across human cell types and tissues.

Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein.