Armin Blesch

Melanoma-inhibiting activity (MIA/CD-RAP) is expressed in a variety of malignant tumors of mainly neuroectodermal origin.

Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair.

Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts.

Nerve growth factor gene therapy for Alzheimer's disease.

Cloning and characterization of the expression pattern of a novel splice product MIA (splice) of malignant melanoma-derived growth-inhibiting activity (MIA/CD-RAP) [corrected].

New strategies in neural repair.

Spontaneous and neurotrophin-induced axonal plasticity after spinal cord injury.

NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection.

Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination.

Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease.

Nucleus hears axon's pain.

Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer.

Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact?

Gene therapy and cell transplantation for Alzheimer's disease and spinal cord injury.

Adult neural progenitor cells provide a permissive guiding substrate for corticospinal axon growth following spinal cord injury.

Axonal responses to cellularly delivered NT-4/5 after spinal cord injury.

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease.

Loss of gene expression in lentivirus- and retrovirus-transduced neural progenitor cells is correlated to migration and differentiation in the adult spinal cord.

Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons.

Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord.

Murine and HIV-based retroviral vectors for in vitro and in vivo gene transfer.

Neurotrophic factors in neurodegeneration.

A neurovascular niche for neurogenesis after stroke.

Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury.

Transient growth factor delivery sustains regenerated axons after spinal cord injury.

GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves.

Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats.

IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury.

Spinal cord injury: plasticity, regeneration and the challenge of translational drug development.

Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery.

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology.

Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation.

A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth.

Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury.

Therapeutic potential of nervous system growth factors for neurodegenerative disease.

Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury.

Promoting directional axon growth from neural progenitors grafted into the injured spinal cord.

Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.

Effects of cavernous nerve reconstruction on expression of nitric oxide synthase isoforms in rats.

Regeneration of long-tract axons through sites of spinal cord injury using templated agarose scaffolds.

Local and remote growth factor effects after primate spinal cord injury.

Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.

TNF: a key neuroinflammatory mediator of neurotoxicity and neurodegeneration in models of Parkinson's disease.

Gene therapy approaches to enhancing plasticity and regeneration after spinal cord injury.

Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: superiority to camp-mediated effects.

Axonal transcription factors signal retrogradely in lesioned peripheral nerve.

Optimization of adult sensory neuron electroporation to study mechanisms of neurite growth.

Neural stem cells for spinal cord repair.

Neurotrophic factors in combinatorial approaches for spinal cord regeneration.

Motor axonal regeneration after partial and complete spinal cord transection.

Intrahippocampal transplantation of mesenchymal stromal cells promotes neuroplasticity.

Long-distance growth and connectivity of neural stem cells after severe spinal cord injury.

Dependence of regenerated sensory axons on continuous neurotrophin-3 delivery.

Axonal transport of neural membrane protein 35 mRNA increases axon growth.

Gene therapy, neurotrophic factors and spinal cord regeneration.

Characterization of supraspinal vasomotor pathways and autonomic dysreflexia after spinal cord injury in F344 rats.

Demonstrating efficacy in preclinical studies of cellular therapies for spinal cord injury - how much is enough?

Bone morphogenetic proteins prevent bone marrow stromal cell-mediated oligodendroglial differentiation of transplanted adult neural progenitor cells in the injured spinal cord.

Partial restoration of cardiovascular function by embryonic neural stem cell grafts after complete spinal cord transection.

Long-term viral brain-derived neurotrophic factor delivery promotes spasticity in rats with a cervical spinal cord hemisection.

Neural stem cell dissemination after grafting to CNS injury sites.

Thoracic rat spinal cord contusion injury induces remote spinal gliogenesis but not neurogenesis or gliogenesis in the brain.

Neural stem cells in models of spinal cord injury.