Deniz Dalkara

Intracytoplasmic delivery of anionic proteins.

Cationic oligonucleotide-peptide conjugates with aggregating properties enter efficiently into cells while maintaining hybridization properties and enzymatic recognition.

Intracellular protein delivery with a dimerizable amphiphile for improved complex stability and prolonged protein release in the cytoplasm of adherent cell lines.

Suppression of cervical carcinoma cell growth by intracytoplasmic codelivery of anti-oncoprotein E6 antibody and small interfering RNA.

Molecular evolution of adeno-associated virus for enhanced glial gene delivery.

Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.

A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells.

Changes in adeno-associated virus-mediated gene delivery in retinal degeneration.

Intravitreal injection of AAV2 transduces macaque inner retina.

AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa.

LiGluR restores visual responses in rodent models of inherited blindness.

Rapid optical control of nociception with an ion-channel photoswitch.

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques.

Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve.

Functional rescue of cone photoreceptors in retinitis pigmentosa.

In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous.

AAV-mediated gene delivery in Dp71-null mouse model with compromised barriers.

Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry.

Gene therapy for inherited retinal degenerations.

Imaging light responses of foveal ganglion cells in the living macaque eye.

Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice.

Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration.

Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment.

Gene therapy for the eye focus on mutation-independent approaches.