Genetics of Skin Carcinogenesis
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Dual regulation of telomerase activity through c-Myc-dependent inhibition and alternative splicing of hTERT.
Journal of cell science Mar, 2002 | Pubmed ID: 11884529
Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation.
Experimental cell research Apr, 2002 | Pubmed ID: 11900490
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas.
International journal of cancer. Journal international du cancer May, 2002 | Pubmed ID: 11992403
The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties.
Journal of virology Feb, 2003 | Pubmed ID: 12525654
Constitutive overexpression of human telomerase reverse transcriptase but not c-myc blocks terminal differentiation in human HaCaT skin keratinocytes.
The Journal of investigative dermatology Jul, 2003 | Pubmed ID: 12839571
The three-dimensional organization of telomeres in the nucleus of mammalian cells.
BMC biology , 2004 | Pubmed ID: 15176976
Authentic fibroblast matrix in dermal equivalents normalises epidermal histogenesis and dermoepidermal junction in organotypic co-culture.
European journal of cell biology Dec, 2004 | Pubmed ID: 15679108
Cell cycle-dependent 3D distribution of telomeres and telomere repeat-binding factor 2 (TRF2) in HaCaT and HaCaT-myc cells.
European journal of cell biology Dec, 2004 | Pubmed ID: 15679112
HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration.
European journal of cell biology Dec, 2004 | Pubmed ID: 15679122
Non-melanoma skin cancer: what drives tumor development and progression?
Carcinogenesis Oct, 2005 | Pubmed ID: 15905207
UV-induced skin cancer: similarities--variations.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG Jul, 2005 | Pubmed ID: 15967008
Skin aging: a role for telomerase and telomere dynamics?
Current molecular medicine Mar, 2005 | Pubmed ID: 15974870
c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2005 | Pubmed ID: 15983382
Automatic telomere length measurements in interphase nuclei by IQ-FISH.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Dec, 2005 | Pubmed ID: 16228977
Telomere-dependent chromosomal instability.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research Nov, 2005 | Pubmed ID: 16358816
Confocal reflection imaging of 3D fibrin polymers.
Blood cells, molecules & diseases Mar-Apr, 2006 | Pubmed ID: 16488165
Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture.
The Journal of investigative dermatology Mar, 2007 | Pubmed ID: 17008882
Reversion of tumor phenotype in surface transplants of skin SCC cells by scaffold-induced stroma modulation.
Carcinogenesis Mar, 2007 | Pubmed ID: 17056607
Epidermal homeostasis in long-term scaffold-enforced skin equivalents.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research Sep, 2006 | Pubmed ID: 17069016
Junctional basement membrane anomalies of skin and mucosa in lipoid proteinosis (hyalinosis cutis et mucosae).
Journal of dermatological science Mar, 2007 | Pubmed ID: 17175139
Telomeres rather than telomerase a key target for anti-cancer therapy?
Experimental dermatology Jan, 2007 | Pubmed ID: 17181645
A novel regulator of telomerase. S100A8 mediates differentiation-dependent and calcium-induced inhibition of telomerase activity in the human epidermal keratinocyte line HaCaT.
The Journal of biological chemistry Mar, 2007 | Pubmed ID: 17197440
The multi-step process of human skin carcinogenesis: a role for p53, cyclin D1, hTERT, p16, and TSP-1.
European journal of cell biology Dec, 2007 | Pubmed ID: 17198740
Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents.
European journal of cell biology Dec, 2007 | Pubmed ID: 17292509
Improved alkaline comet assay protocol for adherent HaCaT keratinocytes to study UVA-induced DNA damage.
Mutation research Jun, 2007 | Pubmed ID: 17509930
Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes.
European journal of cell biology Dec, 2007 | Pubmed ID: 17651862
Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2008 | Pubmed ID: 17898088
Tumor immune escape by the loss of homeostatic chemokine expression.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2007 | Pubmed ID: 18025475
A stable niche supports long-term maintenance of human epidermal stem cells in organotypic cultures.
Stem cells (Dayton, Ohio) Oct, 2008 | Pubmed ID: 18653773
Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1.
Nucleic acids research Nov, 2008 | Pubmed ID: 18835851
Dynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase-negative human cell line.
Molecular biology of the cell Apr, 2009 | Pubmed ID: 19211845
Tissue context-activated telomerase in human epidermis correlates with little age-dependent telomere loss.
Biochimica et biophysica acta Apr, 2009 | Pubmed ID: 19419690
Aging and replicative senescence have related effects on human stem and progenitor cells.
PloS one , 2009 | Pubmed ID: 19513108
Ewing's sarcoma cells with CD57-associated increase of tumorigenicity and with neural crest-like differentiation capacity.
International journal of cancer. Journal international du cancer Sep, 2010 | Pubmed ID: 20104521
Irradiation with heavy-ion particles changes the cellular distribution of human histone acetyltransferase HAT1.
Molecular and cellular biochemistry Jun, 2010 | Pubmed ID: 20148353
An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cells.
Experimental cell research Jul, 2010 | Pubmed ID: 20171964
3D geometry-based quantification of colocalizations in multichannel 3D microscopy images of human soft tissue tumors.
IEEE transactions on medical imaging Aug, 2010 | Pubmed ID: 20562043
A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes.
Molecular biology of the cell Mar, 2011 | Pubmed ID: 21289094
Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors.
Cancer cell Mar, 2011 | Pubmed ID: 21397862
UVA-induced epigenetic regulation of P16(INK4a) in human epidermal keratinocytes and skin tumor derived cells.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Jan, 2012 | Pubmed ID: 21986889
Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis.
Carcinogenesis Jul, 2012 | Pubmed ID: 22461521
Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2012 | Pubmed ID: 22623588
Mechanism of the antiproliferative activity of some naphthalene diimide G-quadruplex ligands.
Molecular pharmacology Feb, 2013 | Pubmed ID: 23188717
An organotypic coculture model supporting proliferation and differentiation of medullary thymic epithelial cells and promiscuous gene expression.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2013 | Pubmed ID: 23269248
WIF1 is expressed by stem cells of the human interfollicular epidermis and acts to suppress keratinocyte proliferation.
The Journal of investigative dermatology Jun, 2013 | Pubmed ID: 23358094
The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres.
EMBO reports Aug, 2013 | Pubmed ID: 23797874
The hallmarks of fibroblast ageing.
Mechanisms of ageing and development Jun, 2014 | Pubmed ID: 24686308
Frailty and telomere length: cross-sectional analysis in 3537 older adults from the ESTHER cohort.
Experimental gerontology Oct, 2014 | Pubmed ID: 25150678
Reproducibility of telomere length assessment: an international collaborative study.
International journal of epidemiology Sep, 2014 | Pubmed ID: 25239152
Wnt-3a-activated human fibroblasts promote human keratinocyte proliferation and matrix destruction.
International journal of cancer. Journal international du cancer Jun, 2015 | Pubmed ID: 25403422
Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.
The Journal of investigative dermatology Aug, 2015 | Pubmed ID: 25815425
Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix.
Tissue engineering. Part C, Methods May, 2015 | Pubmed ID: 25837604
Subcellular Raman Microspectroscopy Imaging of Nucleic Acids and Tryptophan for Distinction of Normal Human Skin Cells and Tumorigenic Keratinocytes.
Analytical chemistry Jul, 2015 | Pubmed ID: 25984831
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