Peter Thorn

Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore.

Modulation of IP(3)-sensitive Ca(2+) release by 2,3-butanedione monoxime.

Zymogen granule exocytosis is characterized by long fusion pore openings and preservation of vesicle lipid identity.

Lysine-fixable dye tracing of exocytosis shows F-actin coating is a step that follows granule fusion in pancreatic acinar cells.

Syncollin is required for efficient zymogen granule exocytosis.

The plasma membrane Q-SNARE syntaxin 2 enters the zymogen granule membrane during exocytosis in the pancreatic acinar cell.

Two phases of zymogen granule lifetime in mouse pancreas: ghost granules linger after exocytosis of contents.

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

The structural integrity of the endoplasmic reticulum, and its possible regulation by inositol 1,3,4,5-tetrakisphosphate.

Ca2+ dynamics in salivary acinar cells: distinct morphology of the acinar lumen underlies near-synchronous global Ca2+ responses.

Agonist-evoked inositol trisphosphate receptor (IP3R) clustering is not dependent on changes in the structure of the endoplasmic reticulum.

A constitutively active nonselective cation conductance underlies resting Ca2+ influx and secretion in bovine adrenal chromaffin cells.

Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cells.

In vivo visualization of albumin degradation in the proximal tubule.

Myosin 2 maintains an open exocytic fusion pore in secretory epithelial cells.

Local dynamic changes in confined extracellular environments within organs.

A multidrug ABC transporter with a taste for salt.

New insights into the control of secretion.

Secretory control: evidence for agonist regulation of post-fusion vesicle behaviour.

Pancreatic acinar cell: new insights into the control of secretion.

Protons released during pancreatic acinar cell secretion acidify the lumen and contribute to pancreatitis in mice.

Exocytosis, dependent on Ca2+ release from Ca2+ stores, is regulated by Ca2+ microdomains.

Hepatocyte growth factor acutely perturbs actin filament anchorage at the epithelial zonula adherens.

Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to-granule fusion.

Measuring calcium signals and exocytosis in tissues.

A simple approach to prepare monodisperse mesoporous silica nanospheres with adjustable sizes.

Molecular control of compound Exocytosis: A key role for VAMP8.

Real-time measurement of F-actin remodelling during exocytosis using Lifeact-EGFP transgenic animals.

Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells.

Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell.

Effects of cell density and biomacromolecule addition on the flow behavior of concentrated mesenchymal cell suspensions.

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids.

The secretory deficit in islets from db/db mice is mainly due to a loss of responding beta cells.

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature.

Measurement of dynamic F-actin changes during exocytosis.

An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery.

Effects of synthetic biomacromolecule addition on the flow behavior of concentrated mesenchymal cell suspensions.

Insulin secretion from beta cells within intact islets: Location matters.