David Vaudry

Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death.

Fast-breaking results on the PACAP/VIP/secretin peptide family in chromaffin cells.

PC12 cells as a model to study the neurotrophic activities of PACAP.

Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP).

Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates endozepine release from cultured rat astrocytes via a PKA-dependent mechanism.

Pituitary adenylate cyclase-activating polypeptide prevents C2-ceramide-induced apoptosis of cerebellar granule cells.

Regulators of cerebellar granule cell development act through specific signaling pathways.

Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation. Neuroprotective effect of C5a against apoptotic cell death.

Pituitary adenylate cyclase-activating polypeptide inhibits caspase-3 activity but does not protect cerebellar granule neurons against beta-amyloid (25-35)-induced apoptosis.

Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells.

Pituitary adenylate cyclase-activating polypeptide prevents the effects of ceramides on migration, neurite outgrowth, and cytoskeleton remodeling.

Endogenous PACAP acts as a stress response peptide to protect cerebellar neurons from ethanol or oxidative insult.

[Effects of PACAP and C2-ceramide on motility of cerebellar granule neurons: the fastest is not the farthest].

N-methyl-D-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells.

Localization and characterization of pituitary adenylate cyclase-activating polypeptide receptors in the human cerebellum during development.

Cycloheximide treatment to identify components of the transitional transcriptome in PACAP-induced PC12 cell differentiation.

The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways.

The delayed rectifier channel current IK plays a key role in the control of programmed cell death by PACAP and ethanol in cerebellar granule neurons.

PACAP and VIP promote initiation of electrophysiological activity in differentiating embryonic stem cells.

PACAP and ceramides exert opposite effects on migration, neurite outgrowth, and cytoskeleton remodeling.

Identification of proteins regulated by PACAP in PC12 cells by 2D gel electrophoresis coupled to mass spectrometry.

PACAP stimulates biosynthesis and release of endozepines from rat astrocytes.

Foreword to special issue: molecular and cellular mechanisms of VIP, PACAP and secretin signaling applied to systems biology.

Ontogeny of PACAP receptors in the human cerebellum: perspectives of therapeutic applications.

PACAP and C2-ceramide generate different AP-1 complexes through a MAP-kinase-dependent pathway: involvement of c-Fos in PACAP-induced Bcl-2 expression.

Neuroprotection by endogenous and exogenous PACAP following stroke.

Neurotrophic effects of PACAP in the cerebellar cortex.

Molecular, cellular, and functional characterizations of pituitary adenylate cyclase-activating polypeptide and its receptors in the cerebellum of New and Old World monkeys.

Novel stable PACAP analogs with potent activity towards the PAC1 receptor.

A cAMP-dependent, protein kinase A-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells.

Biological and structural analysis of truncated analogs of PACAP27.

Peroxiredoxin 2 is involved in the neuroprotective effects of PACAP in cultured cerebellar granule neurons.

Inhibitory effect of PACAP on caspase activity in neuronal apoptosis: a better understanding towards therapeutic applications in neurodegenerative diseases.

Role of complement anaphylatoxin receptors (C3aR, C5aR) in the development of the rat cerebellum.

Latent fluorophores based on a self-immolative linker strategy and suitable for protease sensing.

PACAP prevents toxicity induced by cisplatin in rat and primate neurons but not in proliferating ovary cells: involvement of the mitochondrial apoptotic pathway.

Long-term alterations in vulnerability to addiction to drugs of abuse and in brain gene expression after early life ethanol exposure.

Discovery of pituitary adenylate cyclase-activating polypeptide-regulated genes through microarray analyses in cell culture and in vivo.

Molecular and conformational determinants of pituitary adenylate cyclase-activating polypeptide (PACAP) for activation of the PAC1 receptor.

Paradoxical effect of ethanol on potassium channel currents and cell survival in cerebellar granule neurons.

Role of PACAP in controlling granule cell migration.

Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery.

Biofilm-induced modifications in the proteome of Pseudomonas aeruginosa planktonic cells.

Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum.

Involvement of stathmin 1 in the neurotrophic effects of PACAP in PC12 cells.

Design and in vitro characterization of PAC1/VPAC1-selective agonists with potent neuroprotective effects.

Human duodenal proteome modulations by glutamine and antioxidants.

Identification by photoaffinity labeling of the extracellular N-terminal domain of PAC1 receptor as the major binding site for PACAP.

Pituitary adenylate cyclase-activating polypeptide protects astroglial cells against oxidative stress-induced apoptosis.

Protective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) against apoptosis.

PACAP and a novel stable analog protect rat brain from ischemia: Insight into the mechanisms of action.

Protective effect of the octadecaneuropeptide on hydrogen peroxide-induced oxidative stress and cell death in cultured rat astrocytes.

Effects of an enteral glucose supply on protein synthesis, proteolytic pathways, and proteome in human duodenal mucosa.

Impact of toxicant exposure on the proteomic response to intertidal condition in Mytilus edulis.

Gastric inhibitory polypeptide and its receptor are expressed in the central nervous system and support neuronal survival.

Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the expression and the release of tissue plasminogen activator (tPA) in neuronal cells: involvement of tPA in the neuroprotective effect of PACAP.

High expression of transient receptor potential channels in human breast cancer epithelial cells and tissues: correlation with pathological parameters.

Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.

Light stimuli control neuronal migration by altering of insulin-like growth factor 1 (IGF-1) signaling.

Receptor-independent cellular uptake of pituitary adenylate cyclase-activating polypeptide.

Rescue of neuronal migration deficits in a mouse model of fetal Minamata disease by increasing neuronal Ca2+ spike frequency.

Neurosteroid biosynthesis in the brain of amphibians.

Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides.

Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist.

Cardiotoxin-I: an unexpectedly potent insulinotropic agent.

Spatiotemporal expression and functional implication of CXCL14 in the developing mice cerebellum.

Design and characterization of novel cell-penetrating peptides from pituitary adenylate cyclase-activating polypeptide.

The octadecaneuropeptide ODN protects astrocytes against hydrogen peroxide-induced apoptosis via a PKA/MAPK-dependent mechanism.

An enteral leucine supply modulates human duodenal mucosal proteome and decreases the expression of enzymes involved in fatty acid beta-oxidation.

The stimulatory effect of the octadecaneuropeptide ODN on astroglial antioxidant enzyme systems is mediated through a GPCR.

The octadecaneuropeptide ODN prevents 6-hydroxydopamine-induced apoptosis of cerebellar granule neurons through a PKC-MAPK-dependent pathway.

Spatio-temporal characterization of the pleiotrophinergic system in mouse cerebellum: evidence for its key role during ontogenesis.

Activation of PAC1 Receptors in Rat Cerebellar Granule Cells Stimulates Both Calcium Mobilization from Intracellular Stores and Calcium Influx through N-Type Calcium Channels.

Evaluation of ubiquitinated proteins by proteomics reveals the role of the ubiquitin proteasome system in the regulation of Grp75 and Grp78 chaperone proteins during intestinal inflammation.

Comparison of protein-extraction methods for gills of the shore crab, Carcinus maenas (L.), and application to 2DE.

Enteral glutamine infusion modulates ubiquitination of heat shock proteins, Grp-75 and Apg-2, in the human duodenal mucosa.

Cortical-layer-specific effects of PACAP and tPA on interneuron migration during post-natal development of the cerebellum.

Biochemical characterization of a Caspase-3 far-red fluorescent probe for non-invasive optical imaging of neuronal apoptosis.

Induction of serpinb1a by PACAP or NGF is required for PC12 cells survival after serum withdrawal.

The role of calcium and cyclic nucleotide signaling in cerebellar granule cell migration under normal and pathological conditions.

Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.

Biochemical composition of haemagglutinin-based influenza virus-like particle vaccine produced by transient expression in tobacco plants.

International Union of Basic and Clinical Pharmacology. XCII. Urotensin II, urotensin II-related peptide, and their receptor: from structure to function.

Delayed pituitary adenylate cyclase-activating polypeptide delivery after brain stroke improves functional recovery by inducing m2 microglia/macrophage polarization.

Comparison of the deleterious effects of binge drinking-like alcohol exposure in adolescent and adult mice.

Glutamine enema regulates colonic ubiquitinated proteins but not proteasome activities during TNBS-induced colitis leading to increased mitochondrial activity.

A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.

The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis.

PACAP Enhances Axon Outgrowth in Cultured Hippocampal Neurons to a Comparable Extent as BDNF.

Lycium europaeum fruit extract: antiproliferative activity on a549 human lung carcinoma cells and PC12 rat adrenal medulla cancer cells and assessment of its cytotoxicity on cerebellum granule cells.