Vladimir Kefalov

Signaling States of Rhodopsin in Rod Disk Membranes Lacking Transducin βγ-Complex.

Use of retinal analogues for the study of visual pigment function.

Role of visual pigment properties in rod and cone phototransduction.

Breaking the covalent bond--a pigment property that contributes to desensitization in cones.

Molecular properties of rhodopsin and rod function.

Signaling properties of a short-wave cone visual pigment and its role in phototransduction.

Quantal noise from human red cone pigment.

Intra-retinal visual cycle required for rapid and complete cone dark adaptation.

Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa.

An alternative pathway mediates the mouse and human cone visual cycle.

Functional interchangeability of rod and cone transducin alpha-subunits.

Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability.

Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism.

Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments.

Age-related deterioration of rod vision in mice.

Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons.

The cone-specific visual cycle.

Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle.

Variation in rhodopsin kinase expression alters the dim flash response shut off and the light adaptation in rod photoreceptors.

The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein.

Role of guanylyl cyclase modulation in mouse cone phototransduction.

G-protein betagamma-complex is crucial for efficient signal amplification in vision.

Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches.

Store-operated channels regulate intracellular calcium in mammalian rods.

Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.

Reprogramming of adult rod photoreceptors prevents retinal degeneration.

Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors.

Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse.

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.

An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina.

R9AP overexpression alters phototransduction kinetics in iCre75 mice.

DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.

FASEB Science Research Conference on Biology and Chemistry of Vision.

Ex vivo ERG analysis of photoreceptors using an in vivo ERG system.

Chromophore supply rate-limits mammalian photoreceptor dark adaptation.

Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo.

Human infrared vision is triggered by two-photon chromophore isomerization.

CRALBP supports the mammalian retinal visual cycle and cone vision.

Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling.

Regulation of Mammalian cone phototransduction by recoverin and rhodopsin kinase.

Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.

Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior.