Jun Fujita

Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome.

Invited review: Effects of heat and cold stress on mammalian gene expression.

Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity.

Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets.

A novel protein overexpressed in hepatoma accelerates export of NF-kappa B from the nucleus and inhibits p53-dependent apoptosis.

MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity.

Increased islet apoptosis in Pdx1+/- mice.

Cyclic AMP enhances the expression of an extravillous trophoblast marker, melanoma cell adhesion molecule, in choriocarcinoma cell JEG3 and human chorionic villous explant cultures.

Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma.

Crystallization of gankyrin, an oncoprotein that interacts with CDK4 and the S6b (rpt3) ATPase of the 19S regulator of the 26S proteasome.

Role of a novel oncogenic protein, gankyrin, in hepatocyte proliferation.

PEP-19 overexpression in human uterine leiomyoma.

The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53.

Engineered long terminal repeats of retroviral vectors enhance transgene expression in hepatocytes in vitro and in vivo.

Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury.

A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.

Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas.

Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression.

Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism.

Cardiomyocytes undergo cells division following myocardial infarction is a spatially and temporally restricted event in rats.

[The regenerative therapy of heart failure with adult stem cells and cell transplantation].

Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction.

Increased expression of calcium-binding protein S100 in human uterine smooth muscle tumours.

Purified cardiomyocytes from bone marrow mesenchymal stem cells produce stable intracardiac grafts in mice.

[A case of early esophageal adenocarcinoma arising from cardiac glands, resected by endoscopic mucosal resection].

Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension.

Analysis of the electrophysiological properties and arrhythmias in directly contacted skeletal and cardiac muscle cell sheets.

Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro.

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.

A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor.

The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation.

Mesenchymal, but not hematopoietic, stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction in mice.

Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor cells and transition of bone marrow-derived neuronal cells.

Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase.

Gankyrin: a new oncoprotein and regulator of pRb and p53.

In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo.

G-CSF and HGF: combination of vasculogenesis and angiogenesis synergistically improves recovery in murine hind limb ischemia.

Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1.

Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repair.

Bone marrow derived cells are involved in the pathogenesis of cardiac hypertrophy in response to pressure overload.

The oncoprotein gankyrin interacts with RelA and suppresses NF-kappaB activity.

Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance.

Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine.

Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma.

[Nationwide surveillance of parenteral antibiotics containing meropenem activities against clinically isolated strains in 2006].

Epidemiology of sporadic (non-epidemic) cases of Trichophyton tonsurans infection in Japan based on PCR-RFLP analysis of non-transcribed spacer region of ribosomal RNA gene.

Caspase activity mediates the differentiation of embryonic stem cells.

Analysis of gene and protein expression of cytochrome P450 and stress-associated molecules in rat liver after spaceflight.

G-CSF augments small vessel and cell density in canine myocardial infarciton.

Human T-cell leukemia virus type I tax down-regulates the expression of phosphatidylinositol 3,4,5-trisphosphate inositol phosphatases via the NF-kappaB pathway.

MDM2 is a novel E3 ligase for HIV-1 Vif.

[In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,919 clinical isolates obtained from 72 centers in 2007].

[Evaluation of the factor which has an influence on red blood cell deformability in patients with end-stage renal disease].

Key odor components responsible for the impact on olfactory sense during swine feces composting.

Case of remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome) showing dermatomyositis-like eruption.

[Black esophagus due to acute necrotizing esophagitis: four case reports].

Olecranon bursa with Fusarium solani infection in an otherwise healthy patient.

Wnt2 accelerates cardiac myocyte differentiation from ES-cell derived mesodermal cells via non-canonical pathway.

Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells.

The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage.

HTLV-I Tax regulates the cellular proliferation through the down-regulation of PIP3-phosphatase expressions via the NF-κB pathway.

Treatment of the ventricular tachycardia with engraftment of pluripotent stem cells-derived cardiomyocytes.

Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.

Cold-inducible RNA-binding protein modulates circadian gene expression posttranscriptionally.

In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues.

Myocardial cell sheet therapy and cardiac function.

Human pentraxin 3 (PTX3) as a novel biomarker for the diagnosis of pulmonary arterial hypertension.

Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells.

[Myocardial regeneration with cell transplantation therapy].

Report of the American Heart Association (AHA) Scientific Sessions 2012, Los Angeles.

Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.

Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1.

Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.

Hypothermia protects against fulminant hepatitis in mice by reducing reactive oxygen species production.

(18)F-FDG-PET CT findings in a patient with early-phase cardiac sarcoidosis.

Tumor necrosis factor and transforming growth factor β regulate clock genes by controlling the expression of the cold inducible RNA-binding protein (CIRBP).

[Evaluation of conversion gastrectomy for treatment of Stage IV advanced gastric cancer].

[A case of jejnal cancer who was controlled peritoneal metastasis, successfully by combination therapy with docetaxel and S-1].

[Surgical resection of multiple liver metastases of rectal neuroendocrine tumors].

Generation and characterization of functional cardiomyocytes derived from human T cell-derived induced pluripotent stem cells.

Future prospects for regenerated heart using induced pluripotent stem cells.

Cardiac magnetic resonance imaging in giant cell myocarditis: intriguing associations with clinical and pathological features.

Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions.

Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor.

Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer.

A massive suspension culture system with metabolic purification for human pluripotent stem cell-derived cardiomyocytes.

Involvement of heat shock protein a4/apg-2 in refractory inflammatory bowel disease.

Cold-inducible RNA-binding protein promotes the development of liver cancer.

Heat shock protein A4 controls cell migration and gastric ulcer healing.

Three-dimensional cardiac cine imaging using the kat ARC acceleration: Initial experience in clinical adult patients at 3T.

Dual phosphodiesterase type 5 inhibitor therapy for refractory pulmonary arterial hypertension: a pilot study.

A case of lymphomatoid gastropathy: a self-limited pseudomalignant natural killer (NK)-cell proliferative disease mimicking NK/T-cell lymphomas.

Gelatin Hydrogel Enhances the Engraftment of Transplanted Cardiomyocytes and Angiogenesis to Ameliorate Cardiac Function after Myocardial Infarction.

The Prevalence of Clinically Significant Ischemia in Patients Undergoing Percutaneous Coronary Intervention: A Report from the Multicenter Registry.