Yasuhito Shimada

Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene.

Changes in cyclic nucleotide phosphodiesterase activity and calmodulin concentration in heart muscle of cardiomyopathic hamsters.

Rapid and stable buffer exchange system using InSitu Chip suitable for multicolor and large-scale whole-mount analyses.

[Genomic drug discovery of vascular remodeling].

Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression.

Prior intraperitoneal injection of rat recombinant IL-6 increases hypothalamic IL-6 contents in subsequent forced swim stressor in rats.

Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4.

Pharmacogenomics of cardiovascular pharmacology: pharmacogenomic network of cardiovascular disease models.

Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation.

Synergistic induction of heme oxygenase-1 by nicaraven after subarachnoid hemorrhage to prevent delayed cerebral vasospasm.

In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives.

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity.

Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model.

A novel protocol for the oral administration of test chemicals to adult zebrafish.

Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish.

In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish.

A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening.

Identification of a novel indoline derivative for in vivo fluorescent imaging of blood-brain barrier disruption in animal models.

A novel, reliable method for repeated blood collection from aquarium fish.

Fluorescent-based methods for gene knockdown and functional cardiac imaging in zebrafish.

Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis.

Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation.

Zebrafish-based systems pharmacology of cancer metastasis.

Zebrafish as a systems toxicology model for developmental neurotoxicity testing.

Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression.

Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors.

Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity.

In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish.