Deanna Santer

Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma.

Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis.

Potent induction of IFN-alpha and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus.

C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes.

No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome.

Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes.

Complement, interferon and lupus.

A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans.

Contrasting mechanisms of interferon-α inhibition by intravenous immunoglobulin after induction by immune complexes versus Toll-like receptor agonists.

Enhanced activation of memory, but not naïve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis.

Differential serum levels of eosinophilic eotaxins in primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis.

Immunomodulatory Function of Interleukin 28B during primary infection with cytomegalovirus.

Vaccine adjuvants--understanding molecular mechanisms to improve vaccines.

IL-28B is a key regulator of B- and T-cell vaccine responses against influenza.

Effect of Immunosuppression on T-Helper 2 and B-Cell Responses to Influenza Vaccination.

The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.