Xiang H.-F. Zhang

Sequence information for the splicing of human pre-mRNA identified by support vector machine classification.

Latent splice sites and stop codons revisited.

Computational definition of sequence motifs governing constitutive exon splicing.

Dichotomous splicing signals in exon flanks.

Exon inclusion is dependent on predictable exonic splicing enhancers.

Computational searches for splicing signals.

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity.

Comparison of multiple vertebrate genomes reveals the birth and evolution of human exons.

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.

Positive selection acting on splicing motifs reflects compensatory evolution.

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4.

Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition.

Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing.

Genes that mediate breast cancer metastasis to the brain.

Latent bone metastasis in breast cancer tied to Src-dependent survival signals.

WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis.

Tumor self-seeding by circulating cancer cells.

MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer.

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs.

Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs.

A poised chromatin platform for TGF-β access to master regulators.

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation.

BMP/Coco antagonism as a deterministic factor of metastasis dormancy in lung.

Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma.

Metastasis dormancy in estrogen receptor-positive breast cancer.

Serpins promote cancer cell survival and vascular co-option in brain metastasis.

The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor.

Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis.

The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells.

14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.

Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells.

Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation.

The spliceosome is a therapeutic vulnerability in MYC-driven cancer.

Retrieval of Disseminated Tumor Cells Colonizing the Bone in Murine Breast Cancer Metastasis Models.

Interleukin-17 Could Promote Breast Cancer Progression at Several Stages of the Disease.

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.

Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model.

Devil's Wake: Early-stage bone colonization by breast cancer.

Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.

Fatal attraction: TICs and MDSCs.