Magdalena Karbowniczek

Mutational analysis of the von hippel lindau gene in clear cell renal carcinomas from tuberous sclerosis complex patients.

Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism.

Renal angiomyolipomas from patients with sporadic lymphangiomyomatosis contain both neoplastic and non-neoplastic vascular structures.

Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.

The role of tuberin in cellular differentiation: are B-Raf and MAPK involved?

Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization.

Activation of the mTOR signaling pathway in renal clear cell carcinoma.

mTOR is activated in the majority of malignant melanomas.

Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.

The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development.

Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.

The TSC1/2 complex controls Drosophila pigmentation through TORC1-dependent regulation of catecholamine biosynthesis.

Complement c5a receptor facilitates cancer metastasis by altering T-cell responses in the metastatic niche.

Quantifying autophagosomes and autolysosomes in cells using imaging flow cytometry.

Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs.