Department of Biotechnology
Dr. Pilhan Kim is an Associate Professor of Graduate School of Medical Science and Engineering (GSMSE) at Korea Advanced Institute of Science and Technology (KAIST). He received B.S. and Ph. D. degree in Electrical Engineering from Seoul National University, Korea, in 2000 and 2005, respectively. From 2005 to 2010, he worked as a postdoctoral research fellow at Harvard Medical School, Massachusetts General Hospital Boston, USA, with the cross-disciplinary postdoctoral fellowship from Human Frontier Science Program (HFSP). At 2010, he joined KAIST as a tenure-track faculty and was appointed as a tenured Associate Professor at 2018.
His main research interest is the development of advanced state-of-arts in vivo cellular imaging technology based on a custom-built real-time laser-scanning intravital confocal and two-photon microscopy. Utilizing the image system, his group have achieved a systemic cellular-level visualization of various preclinical animal model to investigate the complex pathophysiology of human diseases and develop novel therapeutics.
A feasible enzymatic process for D-tagatose production by an immobilized thermostable L-arabinose isomerase in a packed-bed bioreactor.
Biotechnology progress Mar-Apr, 2003 | Pubmed ID: 12675579
Effect of overexpression of Actinobacillus succinogenes phosphoenolpyruvate carboxykinase on succinate production in Escherichia coli.
Applied and environmental microbiology Feb, 2004 | Pubmed ID: 14766613
Construction of a shuttle vector for the overexpression of recombinant proteins in Actinobacillus succinogenes.
Plasmid Mar, 2004 | Pubmed ID: 15003707
Long-term effects of fertilization on the forms and availability of soil phosphorus in rice paddy.
Chemosphere Jul, 2004 | Pubmed ID: 15172602
Increased xylitol production rate during long-term cell recycle fermentation of Candida tropicalis.
Biotechnology letters Apr, 2004 | Pubmed ID: 15200170
Current studies on biological tagatose production using L-arabinose isomerase: a review and future perspective.
Applied microbiology and biotechnology Aug, 2004 | Pubmed ID: 15248040
Lactosucrose bioconversion from lactose and sucrose by whole cells of Paenibacillus polymyxa harboring levansucrase activity.
Biotechnology progress Nov-Dec, 2004 | Pubmed ID: 15575726
Functional analysis of sigH expression in Corynebacterium glutamicum.
Biochemical and biophysical research communications Jun, 2005 | Pubmed ID: 15883048
Fly ash effect on improving soil properties and rice productivity in Korean paddy soils.
Bioresource technology Sep, 2006 | Pubmed ID: 16153826
The whcE gene of Corynebacterium glutamicum is important for survival following heat and oxidative stress.
Biochemical and biophysical research communications Nov, 2005 | Pubmed ID: 16212936
Encapsulation method for the dispersion of NiO onto ordered mesoporous silica, SBA-15, using polyethylene oxide (PEO).
Journal of colloid and interface science Mar, 2006 | Pubmed ID: 16223505
Cloning and production of a novel bacteriocin, lactococcin K, from Lactococcus lactis subsp. lactis MY23.
Biotechnology letters Mar, 2006 | Pubmed ID: 16614924
Reducing phosphorus release from paddy soils by a fly ash-gypsum mixture.
Bioresource technology Jul, 2007 | Pubmed ID: 17046246
Excess copper induced physiological and proteomic changes in germinating rice seeds.
Chemosphere Apr, 2007 | Pubmed ID: 17182080
Liming effects on cadmium stabilization in upland soil affected by gold mining activity.
Archives of environmental contamination and toxicology May, 2007 | Pubmed ID: 17253095
Feasibility of phosphate fertilizer to immobilize cadmium in a field.
Chemosphere Feb, 2008 | Pubmed ID: 17977572
Biochemical analysis on the parallel pathways of methionine biosynthesis in Corynebacterium glutamicum.
Journal of microbiology and biotechnology Jun, 2007 | Pubmed ID: 18050920
Expression analysis of the csp-like genes from Corynebacterium glutamicum encoding homologs of the Escherichia coli major cold-shock protein cspA.
Journal of microbiology and biotechnology Aug, 2007 | Pubmed ID: 18051605
5-aminolevulinic acid biosynthesis in Escherichia coli coexpressing NADP-dependent malic enzyme and 5-aminolevulinate synthase.
Journal of microbiology and biotechnology Sep, 2007 | Pubmed ID: 18062242
Characteristics of boron accumulation by fly ash application in paddy soil.
Bioresource technology Sep, 2008 | Pubmed ID: 18194862
Effects of oyster shell on soil chemical and biological properties and cabbage productivity as a liming materials.
Waste management (New York, N.Y.) Dec, 2008 | Pubmed ID: 18294833
A physiology study of Escherichia coli overexpressing phosphoenolpyruvate carboxykinase.
Bioscience, biotechnology, and biochemistry Apr, 2008 | Pubmed ID: 18391462
Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats.
Biological & pharmaceutical bulletin Aug, 2008 | Pubmed ID: 18670089
Heavy metal contamination of arable soil and corn plant in the vicinity of a zinc smelting factory and stabilization by liming.
Archives of environmental contamination and toxicology Feb, 2009 | Pubmed ID: 18704256
Comparative proteomic study of arsenic-induced differentially expressed proteins in rice roots reveals glutathione plays a central role during As stress.
Proteomics Sep, 2008 | Pubmed ID: 18752204
Comparison of the effects of NADH- and NADPH-perturbation stresses on the growth of Escherichia coli.
Current microbiology Feb, 2009 | Pubmed ID: 18953603
Implemented edge shape of an electrical stimulus capsule.
The international journal of medical robotics + computer assisted surgery : MRCAS Mar, 2009 | Pubmed ID: 19170130
LC-MS/MS profiling-based secondary metabolite screening of Myxococcus xanthus.
Journal of microbiology and biotechnology Jan, 2009 | Pubmed ID: 19190408
Preparation and characterization of a PtSn nanocatalyst for use in ethanol electro-oxidation.
Journal of nanoscience and nanotechnology Oct, 2008 | Pubmed ID: 19198405
Effect of industrial by-products containing electron acceptors on mitigating methane emission during rice cultivation.
Waste management (New York, N.Y.) Oct, 2009 | Pubmed ID: 19560334
Potential application of the recombinant Escherichia coli-synthesized heme as a bioavailable iron source.
Journal of microbiology and biotechnology Jun, 2009 | Pubmed ID: 19597319
Comparison of phosphate materials for immobilizing cadmium in soil.
Archives of environmental contamination and toxicology Feb, 2010 | Pubmed ID: 19633979
Molybdenum and tungsten promoted carbons for use as catalyst supports in methanol electro-oxidation.
Journal of nanoscience and nanotechnology May, 2010 | Pubmed ID: 20358965
Escherichia coli arabinose isomerase and Staphylococcus aureus tagatose-6-phosphate isomerase: which is a better template for directed evolution of non-natural substrate isomerization?
Journal of microbiology and biotechnology Jun, 2010 | Pubmed ID: 20622502
Microbial electricity generation of diversified carbonaceous electrodes under variable mediators.
Bioelectrochemistry (Amsterdam, Netherlands) Feb, 2011 | Pubmed ID: 20655812
Novel activity of UDP-galactose-4-epimerase for free monosaccharide and activity improvement by active site-saturation mutagenesis.
Applied biochemistry and biotechnology Feb, 2011 | Pubmed ID: 20717852
Long-term continuous adaptation of Escherichia coli to high succinate stress and transcriptome analysis of the tolerant strain.
Journal of bioscience and bioengineering Jan, 2011 | Pubmed ID: 20829106
Metagenome resource for D-serine utilization in a DsdA-disrupted Escherichia coli.
Journal of microbiology and biotechnology Apr, 2011 | Pubmed ID: 21532320
FrsA functions as a cofactor-independent decarboxylase to control metabolic flux.
Nature chemical biology Jul, 2011 | Pubmed ID: 21623357
Identification of SpiA that interacts with Corynebacterium glutamicum WhcA using a two-hybrid system.
FEMS microbiology letters Sep, 2011 | Pubmed ID: 21623894
Phenol degradation activity and reusability of Corynebacterium glutamicum coated with NH(2)-functionalized silica-encapsulated Fe3O4 nanoparticles.
Bioresource technology Jan, 2012 | Pubmed ID: 22093979
Evaluation of whole lysosomal enzymes directly immobilized on titanium (IV) oxide used in the development of antimicrobial agents.
Enzyme and microbial technology Aug, 2011 | Pubmed ID: 22112509
Toxicity Assessment of Titanium (IV) Oxide Nanoparticles Using Daphnia magna (Water Flea).
Environmental health and toxicology , 2011 | Pubmed ID: 22125763
An engineered Escherichia coli having a high intracellular level of ATP and enhanced recombinant protein production.
Applied microbiology and biotechnology May, 2012 | Pubmed ID: 22173482
Minimal polyketide pathway expression in an actinorhodin cluster-deleted and regulation-stimulated Streptomyces coelicolor.
Journal of industrial microbiology & biotechnology May, 2012 | Pubmed ID: 22252445
Chromium-induced physiological and proteomic alterations in roots of Miscanthus sinensis.
Plant science : an international journal of experimental plant biology May, 2012 | Pubmed ID: 22404839
The role of Corynebacterium glutamicum spiA gene in whcA-mediated oxidative stress gene regulation.
FEMS microbiology letters Jun, 2012 | Pubmed ID: 22443283
Negative role of wblA in response to oxidative stress in Streptomyces coelicolor.
Journal of microbiology and biotechnology Jun, 2012 | Pubmed ID: 22573149
Mitigating global warming potentials of methane and nitrous oxide gases from rice paddies under different irrigation regimes.
Ambio Apr, 2013 | Pubmed ID: 23015326
Role of Electronic Perturbation in Stability and Activity of Pt-based Alloy Nanocatalysts for Oxygen Reduction.
Journal of the American Chemical Society Nov, 2012 | Pubmed ID: 23131009
Porphyrin derivatives from a recombinant Escherichia coli grown on chemically defined medium.
Journal of microbiology and biotechnology Dec, 2012 | Pubmed ID: 23221527
Gibbsiella papilionis sp. nov., isolated from the intestinal tract of the butterfly Mycalesis gotama, and emended description of the genus Gibbsiella.
International journal of systematic and evolutionary microbiology Jul, 2013 | Pubmed ID: 23264501
Adaptive evolution of Corynebacterium glutamicum resistant to oxidative stress and its global gene expression profiling.
Biotechnology letters May, 2013 | Pubmed ID: 23288296
Weissella diestrammenae sp. nov., isolated from the gut of a camel cricket (Diestrammena coreana).
International journal of systematic and evolutionary microbiology Aug, 2013 | Pubmed ID: 23396715
Repression of antibiotic downregulator WblA by AdpA in Streptomyces coelicolor.
Applied and environmental microbiology Jul, 2013 | Pubmed ID: 23603676
Regulatory interaction of the Corynebacterium glutamicum whc genes in oxidative stress responses.
Journal of biotechnology Oct, 2013 | Pubmed ID: 23608553
Effect of gene amplifications in porphyrin pathway on heme biosynthesis in a recombinant Escherichia coli.
Journal of microbiology and biotechnology May, 2013 | Pubmed ID: 23648857
Estimation of phosphoenolpyruvate carboxylation mediated by phosphoenolpyruvate carboxykinase (PCK) in engineered Escherichia coli having high ATP.
Enzyme and microbial technology Jun, 2013 | Pubmed ID: 23683699
Shimia haliotis sp. nov., a bacterium isolated from the gut of an abalone, Haliotis discus hannai.
International journal of systematic and evolutionary microbiology Nov, 2013 | Pubmed ID: 23811138
A WblA-binding protein, SpiA, involved in Streptomyces oxidative stress response.
Journal of microbiology and biotechnology Oct, 2013 | Pubmed ID: 23867703
Enterococcus diestrammenae sp. nov., isolated from the gut of Diestrammena coreana.
International journal of systematic and evolutionary microbiology Dec, 2013 | Pubmed ID: 23907226
Pseudoruegeria haliotis sp. nov., isolated from the gut of the abalone Haliotis discus hannai.
International journal of systematic and evolutionary microbiology Dec, 2013 | Pubmed ID: 23934248
Fractionation and characterization of humic acids from organic amended rice paddy soils.
The Science of the total environment Jan, 2014 | Pubmed ID: 23978588
Genome sequence of the moderately halophilic bacterium Salinicoccus carnicancri type strain Crm(T) (= DSM 23852(T)).
Standards in genomic sciences , 2013 | Pubmed ID: 23991257
Cloacibacterium haliotis sp. nov., isolated from the gut of an abalone, Haliotis discus hannai.
International journal of systematic and evolutionary microbiology Jan, 2014 | Pubmed ID: 24014625
Actinomyces haliotis sp. nov., a bacterium isolated from the gut of an abalone, Haliotis discus hannai.
International journal of systematic and evolutionary microbiology Feb, 2014 | Pubmed ID: 24096355
Evaluating changes in cellulolytic bacterial population to explain methane emissions from air-dried and composted manure treated rice paddy soils.
The Science of the total environment Feb, 2014 | Pubmed ID: 24252202
Methane emission and dynamics of methanotrophic and methanogenic communities in a flooded rice field ecosystem.
FEMS microbiology ecology Apr, 2014 | Pubmed ID: 24410836
Polaribacter atrinae sp. nov., isolated from the intestine of a comb pen shell, Atrina pectinata.
International journal of systematic and evolutionary microbiology May, 2014 | Pubmed ID: 24510977
One-step synthesis of carbon-supported Pd@Pt/C core-shell nanoparticles as oxygen reduction electrocatalysts and their enhanced activity and stability.
Nanoscale Apr, 2014 | Pubmed ID: 24526350
Enhanced electrical contact of microbes using Fe(3)O(4)/CNT nanocomposite anode in mediator-less microbial fuel cell.
Biosensors & bioelectronics Aug, 2014 | Pubmed ID: 24613972
Decolorization and degradation of xenobiotic azo dye Reactive Yellow-84A and textile effluent by Galactomyces geotrichum.
Chemosphere Aug, 2014 | Pubmed ID: 24630455
Soil pH effect on phosphate induced cadmium precipitation in Arable soil.
Bulletin of environmental contamination and toxicology Jul, 2014 | Pubmed ID: 24718500
Endozoicomonas atrinae sp. nov., isolated from the intestine of a comb pen shell Atrina pectinata.
International journal of systematic and evolutionary microbiology Jul, 2014 | Pubmed ID: 24733175
C and N accumulations in soil aggregates determine nitrous oxide emissions from cover crop treated rice paddy soils during fallow season.
The Science of the total environment Aug, 2014 | Pubmed ID: 24880551
Artificial oxidative stress-tolerant Corynebacterium glutamicum.
AMB Express , 2014 | Pubmed ID: 24949252
Acinetobacter apis sp. nov., isolated from the intestinal tract of a honey bee, Apis mellifera.
Journal of microbiology (Seoul, Korea) Aug, 2014 | Pubmed ID: 25098562
Corynebacterium atrinae sp. nov., isolated from the gastrointestinal tract of a pen shell, Atrina pectinata.
International journal of systematic and evolutionary microbiology Feb, 2015 | Pubmed ID: 25404484
Cattle Manure Enhances Methanogens Diversity and Methane Emissions Compared to Swine Manure under Rice Paddy.
PloS one , 2014 | Pubmed ID: 25494364
Impact of Solvent pH on Direct Immobilization of Lysosome-Related Cell Organelle Extracts on TiO₂ for Melanin Treatment.
Journal of microbiology and biotechnology May, 2015 | Pubmed ID: 25502828
Analysis of Heme Biosynthetic Pathways in a Recombinant Escherichia coli.
Journal of microbiology and biotechnology Jun, 2015 | Pubmed ID: 25537720
A comparative study of proteomic differences between pencil and storage roots of sweetpotato (Ipomoea batatas (L.) Lam.).
Plant physiology and biochemistry : PPB / Société française de physiologie végétale Feb, 2015 | Pubmed ID: 25562766
Growth retardation of Escherichia coli by artificial increase of intracellular ATP.
Journal of industrial microbiology & biotechnology Jun, 2015 | Pubmed ID: 25838237
Complete genome sequence of Haloarcula sp. CBA1115 isolated from non-purified solar salts.
Marine genomics Oct, 2015 | Pubmed ID: 25847028
Genomic and phenotypic analyses of Carnobacterium jeotgali strain MS3(T), a lactate-producing candidate biopreservative bacterium isolated from salt-fermented shrimp.
FEMS microbiology letters May, 2015 | Pubmed ID: 25868912
Effect of Rhizobium sp. BARIRGm901 inoculation on nodulation, nitrogen fixation and yield of soybean (Glycine max) genotypes in gray terrace soil.
Bioscience, biotechnology, and biochemistry , 2015 | Pubmed ID: 25996879
High resolution depth distribution of Bacteria, Archaea, methanotrophs, and methanogens in the bulk and rhizosphere soils of a flooded rice paddy.
Frontiers in microbiology , 2015 | Pubmed ID: 26161079
Optimizing the harvesting stage of rye as a green manure to maximize nutrient production and to minimize methane production in mono-rice paddies.
The Science of the total environment Dec, 2015 | Pubmed ID: 26282776
Bizionia fulviae sp. nov., isolated from the gut of an egg cockle, Fulvia mutica.
International journal of systematic and evolutionary microbiology Sep, 2015 | Pubmed ID: 26297143
Genomic Analysis of the Moderately Haloalkaliphilic Bacterium Oceanobacillus kimchii Strain X50T with Improved High-Quality Draft Genome Sequences.
Journal of microbiology and biotechnology Dec, 2015 | Pubmed ID: 26370793
Simplicispira piscis sp. nov., isolated from the gut of a Korean rockfish, Sebastes schlegelii.
International journal of systematic and evolutionary microbiology Dec, 2015 | Pubmed ID: 26400548
Involvement of the osrR gene in the hydrogen peroxide-mediated stress response of Corynebacterium glutamicum.
Research in microbiology Jan, 2016 | Pubmed ID: 26433092
Effective Suppression of Methane Emission by 2-Bromoethanesulfonate during Rice Cultivation.
PloS one , 2015 | Pubmed ID: 26562416
Comamonas piscis sp. nov., isolated from the intestine of a Korean rockfish, Sebastes schlegelii.
International journal of systematic and evolutionary microbiology Nov, 2015 | Pubmed ID: 26612039
Transport, retention, and long-term release behavior of ZnO nanoparticle aggregates in saturated quartz sand: Role of solution pH and biofilm coating.
Water research Mar, 2016 | Pubmed ID: 26741396
Pseudahrensia todarodis sp. nov., isolated from the gut of a Japanese flying squid, Todarodes pacificus.
International journal of systematic and evolutionary microbiology Jan, 2016 | Pubmed ID: 26763785
The Actinobacterium Corynebacterium glutamicum, an Industrial Workhorse.
Journal of microbiology and biotechnology May, 2016 | Pubmed ID: 26838341
Proteus cibarius sp. nov., a swarming bacterium from Jeotgal, a traditional Korean fermented seafood, and emended description of the genus Proteus.
International journal of systematic and evolutionary microbiology Jun, 2016 | Pubmed ID: 26944634
SpiE interacts with Corynebacterium glutamicum WhcE and is involved in heat and oxidative stress responses.
Applied microbiology and biotechnology May, 2016 | Pubmed ID: 26996627
Contrasting effects EDTA applications on the fluxes of methane and nitrous oxide emissions from straw-treated rice paddy soils.
Journal of the science of food and agriculture Mar, 2016 | Pubmed ID: 27010126
The Influence of Active Carbon Supports Toward the Electrocatalytic Behavior of Fe3O4 Nanoparticles for the Extended Energy Generation of Mediatorless Microbial Fuel Cells.
Applied biochemistry and biotechnology Aug, 2016 | Pubmed ID: 27038051
Stimulation of methane oxidation potential and effects on vegetation growth by bottom ash addition in a landfill final evapotranspiration cover.
Waste management (New York, N.Y.) Sep, 2016 | Pubmed ID: 27067424
A Strategy to Increase Microbial Hydrogen Production, Facilitating Intracellular Energy Reserves.
Journal of microbiology and biotechnology Aug, 2016 | Pubmed ID: 27116993
Sedimentitalea todarodis sp. nov., isolated from the intestinal tract of a Japanese flying squid.
International journal of systematic and evolutionary microbiology May, 2016 | Pubmed ID: 27226032
Flexivirga lutea sp. nov., isolated from the feces of a crested ibis, Nipponia nippon, and emended description of genus Flexivirga.
International journal of systematic and evolutionary microbiology Jun, 2016 | Pubmed ID: 27295948
Antimicrobial Properties of Lysosomal Enzymes Immobilized on NH₂Functionalized Silica-Encapsulated Magnetite Nanoparticles.
Journal of nanoscience and nanotechnology Jan, 2016 | Pubmed ID: 27398573
Erratum to: The Actinobacterium Corynebacterium glutamicum, an Industrial Workhorse.
Journal of microbiology and biotechnology Jul, 2016 | Pubmed ID: 27452344
Chronic Repression of mTOR Complex 2 Induces Changes in the Gut Microbiota of Diet-induced Obese Mice.
Scientific reports , 2016 | Pubmed ID: 27471110
Influence of cold stress on contents of soluble sugars, vitamin C and free amino acids including gamma-aminobutyric acid (GABA) in spinach (Spinacia oleracea).
Food chemistry Jan, 2017 | Pubmed ID: 27542466
Carboxyl-terminal domain characterization of polyene-specific P450 hydroxylase in Pseudonocardia autotrophica.
Journal of industrial microbiology & biotechnology Aug, 2016 | Pubmed ID: 27581440
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