Gillian Farnie

The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase.

Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction.

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold.

Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways.

Mammary stem cells and breast cancer--role of Notch signalling.

Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity.

Are stem-like cells responsible for resistance to therapy in breast cancer?

Resistance to endocrine therapy: are breast cancer stem cells the culprits?

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.

Breast cancer stem cells: something out of notching?

Breast cancer stem cells and their role in resistance to endocrine therapy.

P-Cadherin is Co-Expressed with Cd44 and Cd49f and Mediates Stem Cell Properties in Basal-Like Breast Cancer.

A detailed mammosphere assay protocol for the quantification of breast stem cell activity.

Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms.

Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status.

Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells.

Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS).

A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity.

Focal adhesion kinase and Wnt signaling regulate human ductal carcinoma in situ stem cell activity and response to radiotherapy.

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.

Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.

Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis.

Erratum to: Patient-Derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis.