Michelle Bradley

C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages.

LXR-dependent gene expression is important for macrophage survival and the innate immune response.

Lesion macrophages are a key target for the antiatherogenic effects of LXR agonists.

A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development.

Development and validation of a rotor-gene real-time PCR assay for detection, identification, and quantification of Chlamydia trachomatis in a single reaction.

Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon.

Phosphorylation of the liver X receptors.

The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages.

MRI of the ankle: effect on diagnostic confidence and patient management.

Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms.

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE.

N-Acylthiadiazolines, a new class of liver X receptor agonists with selectivity for LXRbeta.

LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow.

TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis.

T0901317, an LXR agonist, augments PKA-induced vascular cell calcification.

Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist.

A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators.

LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target.

Design and synthesis of a library of chemokine antagonists.

The in vitro metabolism of sphingosine-1-phosphate: identification; inhibition and pharmacological implications.

Mortality in carotid sinus hypersensitivity: a cohort study.

Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension.

Monoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven events.

An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol.

The effect of three or six years of denosumab exposure in women with postmenopausal osteoporosis: results from the FREEDOM extension.

The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists.

Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization.

The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists.

The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist.

Functional desensitization of the β 2 adrenoceptor is not dependent on agonist efficacy.

Interim estimates of male human papillomavirus vaccination coverage in the school-based program in Australia.

Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor.

Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.

The Treatment of Chronic Coccydynia and Postcoccygectomy Pain With Pelvic Floor Physical Therapy.