Ulrich Baumann

A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue.

Crystal structure of the human supernatant protein factor.

C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease.

Additive effect of dornase alfa and Nacystelyn on transportability and viscoelasticity of cystic fibrosis sputum.

Targeting of platelet integrin alphaIIbbeta3 determines systemic reaction and bleeding in murine thrombocytopenia regulated by activating and inhibitory FcgammaR.

Production of a functional catalytic antibody ScFv-NusA fusion protein in bacterial cytoplasm.

A mechanism of covalent substrate binding in the x-ray structure of subunit K of the Escherichia coli dihydroxyacetone kinase.

Mucosal vaccination with a recombinant OprF-I vaccine of Pseudomonas aeruginosa in healthy volunteers: comparison of a systemic vs. a mucosal booster schedule.

The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein.

Crystal structure of the Citrobacter freundii dihydroxyacetone kinase reveals an eight-stranded alpha-helical barrel ATP-binding domain.

Supernatant protein factor in complex with RRR-alpha-tocopherylquinone: a link between oxidized Vitamin E and cholesterol biosynthesis.

New insights into the pathophysiology and in vivo function of IgG Fc receptors through gene deletion studies.

Molecular mechanism of enantioselective proton transfer to carbon in catalytic antibody 14D9.

Long term azithromycin therapy in cystic fibrosis patients: a study on drug levels and sputum properties.

Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits.

Expression improvement and mechanistic study of the retro-Diels-Alderase catalytic antibody 10F11 by site-directed mutagenesis.

An efficient one-step site-directed and site-saturation mutagenesis protocol.

Crystal structure of a dodecameric tetrahedral-shaped aminopeptidase.

Cost of care and clinical condition in paediatric cystic fibrosis patients.

Phosphoenolpyruvate- and ATP-dependent dihydroxyacetone kinases: covalent substrate-binding and kinetic mechanism.

Enhanced immunogenicity in the murine airway mucosa with an attenuated Salmonella live vaccine expressing OprF-OprI from Pseudomonas aeruginosa.

Removal of metabolites, cytokines and hepatic growth factors by extracorporeal liver support in children.

. . . And it drags on -- ascites after liver transplantation.

Crystal structure of the phosphoenolpyruvate-binding enzyme I-domain from the Thermoanaerobacter tengcongensis PEP: sugar phosphotransferase system (PTS).

Mechanistic study of proton transfer and hysteresis in catalytic antibody 16E7 by site-directed mutagenesis and homology modeling.

Estimation of central venous pressure by ultrasound.

Preservation of the synthetic and metabolic capacity of isolated human hepatocytes by coculture with human biliary epithelial cells.

Oxidative changes of bronchoalveolar proteins in cystic fibrosis.

The molecular architecture of the metalloprotease FtsH.

Molecular analysis of ulilysin, the structural prototype of a new family of metzincin metalloproteases.

Crystal structure of the nucleotide-binding subunit DhaL of the Escherichia coli dihydroxyacetone kinase.

Regulation of the Dha operon of Lactococcus lactis: a deviation from the rule followed by the Tetr family of transcription regulators.

The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5.

Lectin-reactive alpha-fetoprotein in patients with tyrosinemia type I and hepatocellular carcinoma.

The trouble with biopsies...

Intravenous immunoglobulin (IVIG)-mediated neutralisation of C5a: a direct mechanism of IVIG in the maintenance of a high Fc gammaRIIB to Fc gammaRIII expression ratio on macrophages.

ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells.

Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice.

Magnetic resonance imaging in neonatal hemochromatosis--are we there yet?

Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex.

The Budd-Chiari syndrome in children: the spectrum of management.

Large granular lymphocyte proliferation and revertant mosaicism: two rare events in a Wiskott-Aldrich syndrome patient.

Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study.

A calcium-gated lid and a large beta-roll sandwich are revealed by the crystal structure of extracellular lipase from Serratia marcescens.

The EUROclass trial: defining subgroups in common variable immunodeficiency.

Noninvasive central venous pressure measurement by controlled compression sonography at the forearm.

Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease.

Experience of nitisinone for the pharmacological treatment of hereditary tyrosinaemia type 1.

Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions.

Fatal disseminated toxoplasmosis with congenital transmission in an African migrant.

Neonatal classical galactosaemia presenting as citrin deficiency.

Neuroendocrine carcinoma associated with X-linked hyper-immunoglobulin M syndrome: report of four cases and review of the literature.

Mucosal vaccination against bacterial respiratory infections.

X-ray structures of the three Lactococcus lactis dihydroxyacetone kinase subunits and of a transient intersubunit complex.

Immune responses in the airways by nasal vaccination with systemic boosting against Pseudomonas aeruginosa in chronic lung disease.

Chronic Mycoplasma pneumoniae infection in a child after renal transplantation.

Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site.

A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta.

Non-invasive central venous pressure measurement by compression ultrasound--a step into real life.

Crystal structure of enzyme I of the phosphoenolpyruvate sugar phosphotransferase system in the dephosphorylated state.

The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria.

Systemic, nasal and oral live vaccines against Pseudomonas aeruginosa: a clinical trial of immunogenicity in lower airways of human volunteers.

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.

Successful treatment of autoimmune and lymphoproliferative complications of patients with intrinsic B-cell immunodeficiencies with Rituximab.

The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation.

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome.

On the relevance of the Met-turn methionine in metzincins.

[HIV-infection in children and adolescents].

Expression, purification, crystallization and preliminary X-ray analysis of the EIICGlc domain of the Escherichia coli glucose transporter.

Growth and bone health in chronic liver disease and following liver transplantation in children.

Structure and function of CinD (YtjD) of Lactococcus lactis, a copper-induced nitroreductase involved in defense against oxidative stress.

Crystal structure of archaemetzincin AmzA from Methanopyrus kandleri at 1.5 A resolution.

Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype.

Head-out spirometry accurately monitors the course of Pseudomonas aeruginosa lung infection in mice.

[Assessment of immunoglobulins in a long-term non-interventional study (SIGNS Study). Rationale, design, and methods].

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries.

Central venous pressure and impaired renal function in patients with acute heart failure.

Acceptance and adverse events of the 2009 H1N1 vaccination in immunosuppressed pediatric liver transplant recipients.

Phosphoenolpyruvate: sugar phosphotransferase system from the hyperthermophilic Thermoanaerobacter tengcongensis.

Lung function and inflammation during murine Pseudomonas aeruginosa airway infection.

Structure and function of the bacterial AAA protease FtsH.

Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent.

Endocrine and bone metabolic complications in chronic liver disease and after liver transplantation in children.

Whole-body diffusion-weighted MRI in a case of Rosai-Dorfman disease with exclusive multifocal skeletal involvement.

Diagnosis of nonalcoholic fatty liver disease in children and adolescents: position paper of the ESPGHAN Hepatology Committee.

Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.

Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility.

Ileal exclusion for intractable pruritus in Alagille syndrome.

Biliary atresia.

Hepatic fibrosis in paediatric liver disease.

Structural and biochemical characterization of native and recombinant single insulin-like growth factor-binding domain protein (SIBD-1) from the Central American hunting spider Cupiennius salei (Ctenidae).

Mucosal immunity and nasal influenza vaccination.

Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1β

Molecular basis for the action of the collagen-specific chaperone Hsp47/SERPINH1 and its structure-specific client recognition.

Crystal structures of archaemetzincin reveal a moldable substrate-binding site.

Treatment of neurological autoimmune diseases with immunoglobulins: first insights from the prospective SIGNS registry.

Kinetics of IgM and IgA antibody response to 23-valent pneumococcal polysaccharide vaccination in healthy subjects.

No end in sight: the development of protein crystallography in Martinsried.

Characteristics of early and late PTLD development in pediatric solid organ transplant recipients.

EBV-specific T-cell immunity in pediatric solid organ graft recipients with posttransplantation lymphoproliferative disease.

Heterogeneity of fibrosis patterns in non-alcoholic fatty liver disease supports the presence of multiple fibrogenic pathways.

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome.

Application and limitations of transient liver elastography in children.

Results of single-center screening for chronic hepatitis E in children after liver transplantation and report on successful treatment with ribavirin.

Autophagy-enhancing drug carbamazepine diminishes hepatocellular death in fibrinogen storage disease.

The use of transient elastography and non-invasive serum markers of fibrosis in pediatric liver transplant recipients.

Home monitoring and decision support for international liver transplant children.

Vitamin D deficiency and insufficiency after pediatric liver transplantation.

High-content cytometry and transcriptomic biomarker profiling of human B-cell activation.

Structural characterization of the ribonuclease H-like type ASKHA superfamily kinase MK0840 from Methanopyrus kandleri.

Clinical picture and treatment of 2212 patients with common variable immunodeficiency.

Mutation detection in cholestatic patients using microarray resequencing of ATP8B1 and ABCB11.

Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.

Research and the promotion of child health: a position paper of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

Chronic arthritis in a boy with Cernunnos immunodeficiency.

European Society for Pediatric Gastroenterology, Hepatology, and Nutrition syllabus for subspecialty training: moving towards a European standard.

A diagnostic score for biliary atresia.

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

Liver biopsy in children: position paper of the ESPGHAN Hepatology Committee.

Personal decision-making processes for living related liver transplantation in children.

Indications and limitations of bariatric intervention in severely obese children and adolescents with and without nonalcoholic steatohepatitis: ESPGHAN Hepatology Committee Position Statement.

Adeno-associated virus vector-based gene therapy for monogenetic metabolic diseases of the liver.

Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency.

Selective inhibitors of glutathione transferase P1 with trioxane structure as anticancer agents.

Structural and Biochemical Basis for the Inhibitory Effect of Liprin-α3 on Mouse Diaphanous 1 (mDia1) Function.

The structure of Aquifex aeolicus FtsH in the ADP-bound state reveals a C2-symmetric hexamer.

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota.

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies.

Automatic Measurement of Venous Pressure Using B-Mode Ultrasound.

Structural Basis of Proline-Proline Peptide Bond Specificity of the Metalloprotease Zmp1 Implicated in Motility of Clostridium difficile.

Helical Symmetry of Nucleic Acids: Obstacle or Help in Structure Solution?

Molecular imaging of glutamate-carboxypeptidase II (prostate-specific membrane antigen) in malignant epithelioid hemangioendothelioma.

Nijmegen Breakage Syndrome: Clinical and Immunological Features, Long-Term Outcome and Treatment Options - a Retrospective Analysis.

Improvement of BMI after Lifestyle Intervention Is Associated with Normalisation of Elevated ELF Score and Liver Stiffness in Obese Children.

Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency.

Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis.

The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1.

The first crystal structure of the peptidase domain of the U32 peptidase family.

Portal inflammation is independently associated with fibrosis and metabolic syndrome in pediatric nonalcoholic fatty liver disease.

Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation.

Feeding Anthrax: The Crystal Structure of Bacillus anthracis InhA Protease.

Circulating miR-21 and miR-29a as Markers of Disease Severity and Etiology in Cholestatic Pediatric Liver Disease.

Hepatitis E in Children: A Position Paper by the ESPGHAN Hepatology Committee.

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair.

Treatment of patients with multifocal motor neuropathy with immunoglobulins in clinical practice: the SIGNS registry.

Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins.

Oral Tocofersolan Corrects or Prevents Vitamin E Deficiency in Children With Chronic Cholestasis.

Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN).

Matched-pair analysis: identification of factors with independent influence on the development of PTLD after kidney or liver transplantation.

The Benefit of Sleeve Gastrectomy in Obese Adolescents on Nonalcoholic Steatohepatitis and Hepatic Fibrosis.