Andreas Unterberg

Current recommendations for neurotrauma.

Decreased hemispheric Aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats.

Temporal profile of cortical perfusion and microcirculation after controlled cortical impact injury in rats.

Bedside microdialysis: a tool to monitor cerebral metabolism in subarachnoid hemorrhage patients?

Selective neck occlusion of a large complex aneurysm of the middle cerebral artery trifurcation with the UltraSoft coil.

Osteochondroma of the cervical spine--a surprising finding in a liver transplanted patient with polyneuropathy and polyradiculitis: case report.

Norepinephrine-induced hyperglycemia does not increase cortical lactate in brain-injured rats.

Focal laminar cortical MR signal abnormalities after subarachnoid hemorrhage.

Influence of norepinephrine and dopamine on cortical perfusion, EEG activity, extracellular glutamate, and brain edema in rats after controlled cortical impact injury.

Pulmonary air embolism in severe head injury.

New European Directive on clinical trials.

Acute focal neurological deficits in aneurysmal subarachnoid hemorrhage: relation of clinical course, CT findings, and metabolite abnormalities monitored with bedside microdialysis.

Effects of LY379268, a selective group II metabotropic glutamate receptor agonist on EEG activity, cortical perfusion, tissue damage, and cortical glutamate, glucose, and lactate levels in brain-injured rats.

Effects of early and late intravenous norepinephrine infusion on cerebral perfusion, microcirculation, brain-tissue oxygenation, and edema formation in brain-injured rats.

Norepinephrine infusion increases interleukin-6 in plasma and cerebrospinal fluid of brain-injured rats.

Neuromonitoring: brain oxygenation and microdialysis.

New European directive on clinical trials: implications for traumatic head injury research.

Differential concentration-dependent effects of prolonged norepinephrine infusion on intraparenchymal hemorrhage and cortical contusion in brain-injured rats.

Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.

Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome.

Consensus meeting on microdialysis in neurointensive care.

Small volume resuscitation with HyperHaes improves pericontusional perfusion and reduces lesion volume following controlled cortical impact injury in rats.

Using video-oculography for galvanic evoked vestibulo-ocular monitoring in comatose patients.

The effect of N-acetylcysteine on posttraumatic changes after controlled cortical impact in rats.

Different angiogenic phenotypes in primary and secondary glioblastomas.

Contemporary management of aneurysmal subarachnoid hemorrhage in germany: results of a survey among 100 neurosurgical departments.

Motor cortex stimulation for long-term relief of chronic neuropathic pain: a 10 year experience.

Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours.

Antiglioma activity of 2,2':6',2"-terpyridineplatinum(II) complexes in a rat model--effects on cellular redox metabolism.

Detecting and treating microvascular ischemia after subarachnoid hemorrhage.

Recommendations for the management of intracranial haemorrhage - part I: spontaneous intracerebral haemorrhage. The European Stroke Initiative Writing Committee and the Writing Committee for the EUSI Executive Committee.

Uniform MDM2 overexpression in a panel of glioblastoma multiforme cell lines with divergent EGFR and p53 expression status.

Comparative analysis of in vitro conditions for rat adult neural progenitor cells.

Effects of mannitol bolus administration on intracranial pressure, cerebral extracellular metabolites, and tissue oxygenation in severely head-injured patients.

Surgical treatment of intracerebral haemorrhage.

The role of surgery in ischemic stroke: decompressive surgery.

Identification of early markers for symptomatic vasospasm in human cerebral microdialysate after subarachnoid hemorrhage: preliminary results of a proteome-wide screening.

Heterogeneous regional and temporal energetic impairment following controlled cortical impact injury in rats.

Tacrolimus depresses local immune cell infiltration but fails to reduce cortical contusion volume in brain-injured rats.

Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY): a randomized, controlled trial.

Clinical review: Therapy for refractory intracranial hypertension in ischaemic stroke.

Stem cell marker CD133 affects clinical outcome in glioma patients.

MRI of the perihemorrhagic zone in a rat ICH model: effect of hematoma evacuation.

SU11657 enhances radiosensitivity of human meningioma cells.

Trauma care in Germany: a European perspective.

Characteristics of thoracolumbar intramedullary subependymomas.

Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib.

Pathogenetic pathways leading to glioblastoma multiforme: association between gene expressions and resistance to erlotinib.

Candidate genes for sensitivity and resistance of human glioblastoma multiforme cell lines to erlotinib. Laboratory investigation.

Decompressive surgery for severe brain edema.

Preliminary evidence that ketamine inhibits spreading depolarizations in acute human brain injury.

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients.

Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: where do we stand?

Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient.

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival.

Anticonvulsive effects of the dopamine agonist lisuride maleate after experimental traumatic brain injury.

Attitude and opinion of neurosurgeons concerning protective bicycle-helmet use.

Non-randomized therapy trial to determine the safety and efficacy of heavy ion radiotherapy in patients with non-resectable osteosarcoma.

Differentiation therapy exerts antitumor effects on stem-like glioma cells.

Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation.

Helmet use in winter sport activities--attitude and opinion of neurosurgeons and non-traumatic-brain-injury-educated persons.

Intensive care management of acute stroke: surgical treatment.

The use of danaparoid to manage coagulopathy in a neurosurgical patient with heparin-induced thrombocytopenia type II and intracerebral haemorrhage.

Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.

Fast point-of-care coagulometer guided reversal of oral anticoagulation at the bedside hastens management of acute subdural hemorrhage.

Randomised phase I/II study to evaluate carbon ion radiotherapy versus fractionated stereotactic radiotherapy in patients with recurrent or progressive gliomas: the CINDERELLA trial.

Treatment of patients with atypical meningiomas Simpson grade 4 and 5 with a carbon ion boost in combination with postoperative photon radiotherapy: the MARCIE trial.

One life ends, another begins: Management of a brain-dead pregnant mother-A systematic review-.

Evaluation of a novel brain tissue oxygenation probe in an experimental swine model.

Reversible occlusion (on-off) valves in shunted tumor patients.

Proteomics of human cerebral microdialysate: From detection of biomarkers to clinical application.

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas.

DESTINY II: DEcompressive Surgery for the Treatment of malignant INfarction of the middle cerebral arterY II.

Comparative study of application accuracy of two frameless neuronavigation systems: experimental error assessment quantifying registration methods and clinically influencing factors.

Association of stem cell-related markers and survival in astrocytic gliomas.

Neurosurgical intensive care unit--essential for good outcomes in neurosurgery?

Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived TGF-β.

Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas.

Expression and regulation of AC133 and CD133 in glioblastoma.

Low-frequency sampling for PRx calculation does not reduce prognostication and produces similar CPPopt in intracerebral haemorrhage patients.

Cerebral metabolism after early decompression craniotomy following controlled cortical impact injury in rats.

Quantitative sensory testing in patients with chronic unilateral radicular neuropathic pain and active spinal cord stimulation.

Intraoperative indocyanine green angiography for microsurgical treatment of a craniocervical dural arteriovenous fistula.

Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas.

The differential diagnosis and treatment of normal-pressure hydrocephalus.

Pressure reactivity index correlates with metabolic dysfunction in a porcine model of intracerebral hemorrhage.

Evidence of spreading depolarizations in a porcine cortical intracerebral hemorrhage model.

Influence of isoflurane on neuronal death and outcome in a rat model of traumatic brain injury.

Spreading depolarizations in a case of migraine-related stroke.

No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas.

Brain tissue oxygen monitoring and hyperoxic treatment in patients with traumatic brain injury.

Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury.

'Long' pressure reactivity index (L-PRx) as a measure of autoregulation correlates with outcome in traumatic brain injury patients.

Dissecting the genomic complexity underlying medulloblastoma.

Clinical review: Traumatic brain injury in patients receiving antiplatelet medication.

Delayed cerebral ischemia after subarachnoid hemorrhage: from vascular spasm to cortical spreading depolarizations.

Cerebral glucose and spreading depolarization in patients with aneurysmal subarachnoid hemorrhage.

Potential canonical wnt pathway activation in high-grade astrocytomas.

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Deep brain stimulation of the lateral habenular complex in treatment-resistant depression: traps and pitfalls of trajectory choice.

Stroke-related Early Tracheostomy versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): a randomized pilot trial.

Clusters of spreading depolarizations are associated with disturbed cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage.

European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.

Cortical spreading depression dynamics can be studied using intrinsic optical signal imaging in gyrencephalic animal cortex.

Stereotactic biopsy and drainage of a brainstem abscess caused by Listeria monocytogenes.

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Initial experiences with Multiplate® for rapid assessment of antiplatelet agent activity in neurosurgical emergencies.

Multiple electrode aggregometry in antiplatelet-related intracerebral haemorrhage.

Lessons from the intracranial pressure-monitoring trial in patients with traumatic brain injury.

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry.

Pre-chiasmatic transection of the optic nerve can save contralateral vision in patients with optic nerve sheath meningioms.

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system.

Rapid bedside coagulometry prior to urgent neurosurgical procedures in anticoagulated patients.

Delayed anticoagulation-related intracranial haemorrhage after minor head injury.

Towards optimizing the sequence of bevacizumab and nitrosoureas in recurrent malignant glioma.

Decompressive craniectomy in patients with aneurysmal subarachnoid hemorrhage: a single-center matched-pair analysis.

Prothrombin complex concentrate facilitates emergency spinal surgery in anticoagulated patients.

Hemicraniectomy in older patients with extensive middle-cerebral-artery stroke.

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Endogenous nitric-oxide synthase inhibitor ADMA after acute brain injury.

Aberrant self-renewal and quiescence contribute to the aggressiveness of glioblastoma.

The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex.

Minimally invasive endoscopic surgery for treatment of spontaneous intracerebral hematomas: a single-center analysis.

Radial, spiral and reverberating waves of spreading depolarization occur in the gyrencephalic brain.

Hemicraniectomy for middle-cerebral-artery stroke. Author reply.

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma.

Perihemorrhagic ischemia occurs in a volume-dependent manner as assessed by multimodal cerebral monitoring in a porcine model of intracerebral hemorrhage.

Rapid Anticoagulation Reversal With Prothrombin Complex Concentrate Before Emergency Brain Tumor Surgery.

Cerebral Glucose Metabolism and Sedation in Brain-injured Patients: A Microdialysis Study.

European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage.

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.

Surgical aspects of decompression craniectomy in malignant stroke: review.

Point of care coagulation testing in neurosurgery.

Emergency neurosurgical care in patients treated with apixaban: report of 2 cases.

Minimally invasive endoscopic surgery for treatment of spontaneous intracerebral haematomas.

Early Surgery versus Initial Conservative Treatment in Patients with Traumatic Intracerebral Hemorrhage (STITCH[Trauma]): The First Randomized Trial.

The Hemodynamic Response of Spreading Depolarization Observed by Near Infrared Spectroscopy After Aneurysmal Subarachnoid Hemorrhage.

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain.

Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma.

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients.

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Rivaroxaban and intracranial haemorrhage after mild traumatic brain injury: A dangerous combination?

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities.

Intracranial haemorrhage in patients treated with direct oral anticoagulants.

Anticoagulation Reversal with Prothrombin Complex Concentrate in Aneurysmal Subarachnoid Hemorrhage.

Radiosensitivity of Patient-Derived Glioma Stem Cell 3-Dimensional Cultures to Photon, Proton, and Carbon Irradiation.

Surgical Trial In Traumatic intraCerebral Haemorrhage (STITCH): a randomised controlled trial of Early Surgery compared with Initial Conservative Treatment.

Against the Odds: Massive Lumbar Intradural Disk Herniation in the Elderly.

Low-grade Glioma Surgery in Intraoperative Magnetic Resonance Imaging: Results of a Multicenter Retrospective Assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.

Ventriculo-bipleural shunt as last resort in a 4-year-old child in whom a VP and VA shunt failed.

Intracranial tumour haemorrhage following intravenous thrombolysis.

Distal catheter migration of a direct ventriculo-auricular shunt.

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.

Prognostic factors and long-term survival in surgically treated brain metastases from non-small cell lung cancer.

Is a modification of the radiotherapeutic target volume necessary after resection of glioblastomas with opening of the ventricles?

Methylation-based classification of benign and malignant peripheral nerve sheath tumors.

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients.

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade.

Factors triggering an additional resection and determining residual tumor volume on intraoperative MRI: analysis from a prospective single-center registry of supratentorial gliomas.

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients.

Assessing perioperative complications associated with use of intraoperative magnetic resonance imaging during glioma surgery - a single centre experience with 516 cases.

Radiotherapy plus concomitant temozolomide in primary gliosarcoma.

Evaluation of neuropsychological outcome and "quality of life" after glioma surgery.

Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.

MR Angiography at 7T to Visualize Cerebrovascular Territories.

Ketamine modulation of the haemodynamic response to spreading depolarization in the gyrencephalic swine brain.

Evaluation of a New Brain Tissue Probe for Intracranial Pressure, Temperature, and Cerebral Blood Flow Monitoring in Patients with Aneurysmal Subarachnoid Hemorrhage.

Changes in electrocorticographic beta frequency components precede spreading depolarization in patients with acute brain injury.

Visualization of pressure related vessel compression in the perihemorrhagic zone during endoscopic ICH evacuation.

Prognostic value of the extent of resection in supratentorial WHO grade II astrocytomas stratified for IDH1 mutation status: a single-center volumetric analysis.

Subcutaneous trigeminal nerve field stimulation for refractory trigeminal pain: a cohort analysis.

Automatic Analysis of Cellularity in Glioblastoma and Correlation with ADC Using Trajectory Analysis and Automatic Nuclei Counting.

Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension.

Evaluation of a New Brain Tissue Probe for Cerebral Blood Flow Monitoring in an Experimental Pig Model.

Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features.

Large field-of-view movement-compensated intrinsic optical signal imaging for the characterization of the haemodynamic response to spreading depolarizations in large gyrencephalic brains.

Incidence, hemodynamic, and electrical characteristics of spreading depolarization in a swine model are affected by local but not by intravenous application of magnesium.

Development and Validation of an Automatic Segmentation Algorithm for Quantification of Intracerebral Hemorrhage.

Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone.

Use of GABAergic sedatives after subarachnoid hemorrhage is associated with worse outcome-preliminary findings.

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas.

Tumor Infiltration in Enhancing and Non-Enhancing Parts of Glioblastoma: A Correlation with Histopathology.

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo.

Prospective analysis of neuropsychological deficits following resection of benign skull base meningiomas.

Does suboccipital decompression and evacuation of intraparenchymal hematoma improve neurological outcome in patients with spontaneous cerebellar hemorrhage?

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis.

Identification of T cell target antigens in glioblastoma stem-like cells using an integrated proteomics-based approach in patient specimens.

Point-of-Care Testing in Neurosurgery.