Siu Kwan Sze

Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue.

Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy.

Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry.

Plasma electron capture dissociation for the characterization of large proteins by top down mass spectrometry.

Detection of four oxidation sites in viral prolyl-4-hydroxylase by top-down mass spectrometry.

Nanosecond laser-induced photochemical oxidation method for protein surface mapping with mass spectrometry.

Microwave-assisted specific chemical digestion for rapid protein identification.

Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells.

Automated intensity descent algorithm for interpretation of complex high-resolution mass spectra.

Cyclooxygenase-2 inhibition increases mortality, enhances left ventricular remodeling, and impairs systolic function after myocardial infarction in the pig.

Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells.

Novel polymer composite to eliminate background matrix ions in matrix assisted laser desorption/ionization-mass spectrometry.

A comparative study of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) versus SCX-IMAC-based methods for phosphopeptide isolation/enrichment.

Hybridization of pulsed-Q dissociation and collision-activated dissociation in linear ion trap mass spectrometer for iTRAQ quantitation.

One-step procedure for peptide extraction from in-gel digestion sample for mass spectrometric analysis.

Elucidating the structure of cyclotides by partial acid hydrolysis and LC-MS/MS analysis.

Elucidating in vivo structural dynamics in integral membrane protein by hydroxyl radical footprinting.

Identification of novel functional differences in monocyte subsets using proteomic and transcriptomic methods.

Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics.

Local atherosclerotic plaques are a source of prognostic biomarkers for adverse cardiovascular events.

Simultaneous characterization of glyco- and phosphoproteomes of mouse brain membrane proteome with electrostatic repulsion hydrophilic interaction chromatography.

Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.

Quantitative iTRAQ secretome analysis of cellulolytic Thermobifida fusca.

Novel application of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) in shotgun proteomics: comprehensive profiling of rat kidney proteome.

Study of monocyte membrane proteome perturbation during lipopolysaccharide-induced tolerance using iTRAQ-based quantitative proteomic approach.

Quantitative iTRAQ secretome analysis of Aspergillus niger reveals novel hydrolytic enzymes.

High myeloid-related protein: 8/14 levels are related to an increased risk of cardiovascular events after carotid endarterectomy.

Quantitative proteomics discloses MET expression in mitochondria as a direct target of MET kinase inhibitor in cancer cells.

Angiopoietin-like 4 interacts with matrix proteins to modulate wound healing.

Global molecular dysfunctions in gastric cancer revealed by an integrated analysis of the phosphoproteome and transcriptome.

Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events.

CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.

Simultaneous analysis of proteome, phospho- and glycoproteome of rat kidney tissue with electrostatic repulsion hydrophilic interaction chromatography.

Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum.

Investigation of POPX2 phosphatase functions by comparative phosphoproteomic analysis.

Comparative proteome analysis of 3T3-L1 adipocyte differentiation using iTRAQ-coupled 2D LC-MS/MS.

iTRAQ-based quantitative proteomic analysis of Thermobifida fusca reveals metabolic pathways of cellulose utilization.

Detection, evaluation and minimization of nonenzymatic deamidation in proteomic sample preparation.

Proteomic analysis of pH and strains dependent protein secretion of Trichoderma reesei.

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe.

iTRAQ-based quantitative secretome analysis of Phanerochaete chrysosporium.

Elucidating structural dynamics of integral membrane proteins on native cell surface by hydroxyl radical footprinting and nano LC-MS/MS.

Application of electrostatic repulsion hydrophilic interaction chromatography to the characterization of proteome, glycoproteome, and phosphoproteome using nano LC-MS/MS.

Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers.

Myostatin induces degradation of sarcomeric proteins through a Smad3 signaling mechanism during skeletal muscle wasting.

Electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) versus strong cation exchange (SCX) for fractionation of iTRAQ-labeled peptides.

Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum.

Phenotyping of tianma-stimulated differentiated rat neuronal b104 cells by quantitative proteomics.

Quantitative proteomic analysis of lignocellulolytic enzymes by Phanerochaete chrysosporium on different lignocellulosic biomass.

Neuronal p60TRP expression modulates cardiac capacity.

Enhanced Separation and Characterization of Deamidated Peptides with RP-ERLIC-Based Multidimensional Chromatography Coupled with Tandem Mass Spectrometry.

Synergism between curdlan and GM-CSF confers a strong inflammatory signature to dendritic cells.

Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin.

Metabolic adaptation to a disruption in oxygen supply during myocardial ischemia and reperfusion is underpinned by temporal and quantitative changes in the cardiac proteome.

Quantitative secretomic analysis of Trichoderma reesei strains reveals enzymatic composition for lignocellulosic biomass degradation.

New insights into the brain protein metabolism of Gastrodia elata-treated rats by quantitative proteomics.

Multidimensional identification of tissue biomarkers of gastric cancer.

Label free quantitative proteomic analysis of secretome by Thermobifida fusca on different lignocellulosic biomass.

Myostatin is a novel tumoral factor that induces cancer cachexia.

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.

Tianma modulates proteins with various neuro-regenerative modalities in differentiated human neuronal SH-SY5Y cells.

Gastrodia elata Blume (tianma) mobilizes neuro-protective capacities.

Tianma modulates blood vessel tonicity.

Elucidating the temporal dynamics of chromatin-associated protein release upon DNA digestion by quantitative proteomic approach.

Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome.

Quantitative proteomic analysis of secretome of microbial consortium during saw dust utilization.

Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT).

Hypoxia modulates A431 cellular pathways association to tumor radioresistance and enhanced migration revealed by comprehensive proteomic and functional studies.

Deletion of Synechocystis sp. PCC6803 Leader Peptidase LepB1 Affects Photosynthetic Complexes and Respiration.

Brain-site-specific proteome changes induced by neuronal P60TRP expression.

Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular disease.

Comparative evaluation of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) and high-pH reversed phase (Hp-RP) chromatography in profiling of rat kidney proteome.

Scalable and effective enrichment of semiconducting single-walled carbon nanotubes by a dual selective naphthalene-based azo dispersant.

Protein abundance in multiplexed samples (PAMUS) for quantitation of Trichoderma reesei secretome.

Integrative transcriptome and proteome study to identify the signaling network regulated by POPX2 phosphatase.

Proteomic analysis of temperature dependent extracellular proteins from Aspergillus fumigatus grown under solid-state culture condition.

Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling.

Quantitative clinical proteomic study of autopsied human infarcted brain specimens to elucidate the deregulated pathways in ischemic stroke pathology.

Brain site-specific proteome changes in aging-related dementia.

Serum extracellular vesicle protein levels are associated with acute coronary syndrome.

Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase.

Correction of errors in tandem mass spectrum extraction enhances phosphopeptide identification.

Acetylation at lysine 183 of progesterone receptor by p300 accelerates DNA binding kinetics and transactivation of direct target genes.

Quantitative profiling of the rat heart myoblast secretome reveals differential responses to hypoxia and re-oxygenation stress.

Lysine methylation of progesterone receptor at activation function 1 regulates both ligand-independent activity and ligand sensitivity of the receptor.

Novel pathophysiological markers are revealed by iTRAQ-based quantitative clinical proteomics approach in vascular dementia.

Plasma biomarker discovery in preeclampsia using a novel differential isolation technology for circulating extracellular vesicles.

LEO1 is regulated by PRL-3 and mediates its oncogenic properties in acute myelogenous leukemia.

Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma.

Deep proteomic profiling of human carotid atherosclerotic plaques using multidimensional LC-MS/MS.

Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.

Hypoxia-induced changes to integrin α 3 glycosylation facilitate invasion in epidermoid carcinoma cell line A431.

Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis.

iTRAQ quantitative clinical proteomics revealed role of Na(+)K(+)-ATPase and its correlation with deamidation in vascular dementia.

Study of Phanerochaete chrysosporium secretome revealed protein glycosylation as a substrate-dependent post-translational modification.

Proteomic analysis of protein deamidation.

Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle.

Evaluation of the effect of trypsin digestion buffers on artificial deamidation.

Temporal lobe proteins implicated in synaptic failure exhibit differential expression and deamidation in vascular dementia.

Multiplex imaging and cellular target identification of kinase inhibitors via an affinity-based proteome profiling approach.

Quantitative proteomic study of Aspergillus Fumigatus secretome revealed deamidation of secretory enzymes.

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.

Differential association of chromatin proteins identifies BAF60a/SMARCD1 as a regulator of embryonic stem cell differentiation.

Simultaneous Enrichment of Plasma Soluble and Extracellular Vesicular Glycoproteins Using Prolonged Ultracentrifugation-Electrostatic Repulsion-hydrophilic Interaction Chromatography (PUC-ERLIC) Approach.

Improving Blood Plasma Glycoproteome Coverage by Coupling Ultracentrifugation Fractionation to Electrostatic Repulsion-Hydrophilic Interaction Chromatography Enrichment.

Data for iTRAQ secretomic analysis of Aspergillus fumigatus in response to different carbon sources.

Uncovering Neurodegenerative Protein Modifications via Proteomic Profiling.

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.

Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR).

The diagnostic and prognostic potential of plasma extracellular vesicles for cardiovascular disease.

Cysteine-Rich Peptide Family with Unusual Disulfide Connectivity from Jasminum sambac.

Recent advances in mass spectrometric analysis of protein deamidation.

Plasma proteome coverage is increased by unique peptide recovery from sodium deoxycholate precipitate.

Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms.

Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues.

MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA.

A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides.

Data for iTRAQ profiling of micro-vesicular plasma specimens: In search of potential prognostic circulatory biomarkers for Lacunar infarction.

Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease.

Drosophila expressing human SOD1 successfully recapitulates mitochondrial phenotypic features of familial amyotrophic lateral sclerosis.

Commercial processed soy-based food product contains glycated and glycoxidated lunasin proteoforms.

Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.

Plasma-derived Extracellular Vesicles Contain Predictive Biomarkers and Potential Therapeutic Targets for Myocardial Ischemic (MI) Injury.

Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein.

Proteomics study revealed altered proteome of Dichogaster curgensis upon exposure to fly ash.

Proteome mapping of Plasmodium: identification of the P. yoelii remodellome.

Characterization of Glutamine Deamidation by Long-Length Electrostatic Repulsion-Hydrophilic Interaction Chromatography-Tandem Mass Spectrometry (LERLIC-MS/MS) in Shotgun Proteomics.

Irradiation of Epithelial Carcinoma Cells Upregulates Calcium-Binding Proteins That Promote Survival under Hypoxic Conditions.

Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profiling.

Ginkgotides: Proline-Rich Hevein-Like Peptides from Gymnosperm Ginkgo biloba.

Corrigendum: Proteome mapping of Plasmodium: identification of the P. yoelii remodellome.

Structural insights into the LCIB protein family reveals a new group of β-carbonic anhydrases.

Phosphatase POPX2 Exhibits Dual Regulatory Functions in Cancer Metastasis.

Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers.