Manuel Mayr

Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice.

Mechanical stress-induced DNA damage and rac-p38MAPK signal pathways mediate p53-dependent apoptosis in vascular smooth muscle cells.

Active and passive smoking, chronic infections, and the risk of carotid atherosclerosis: prospective results from the Bruneck Study.

Smooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells.

Both donor and recipient origins of smooth muscle cells in vein graft atherosclerotic lesions.

Increased risk of atherosclerosis is confined to CagA-positive Helicobacter pylori strains: prospective results from the Bruneck study.

Mechanical stretch-induced apoptosis in smooth muscle cells is mediated by beta1-integrin signaling pathways.

Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis.

Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta.

Loss of PKC-delta alters cardiac metabolism.

Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice.

Pitfalls of proteomics.

Vascular proteomics: linking proteomic and metabolomic changes.

Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism.

Proteomic dataset of Sca-1+ progenitor cells.

Proteomic dataset of mouse aortic smooth muscle cells.

Role of oxidative stress in angiotensin-II mediated contraction of human conduit arteries in patients with cardiovascular disease.

Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study.

Proteomics-based development of biomarkers in cardiovascular disease: mechanistic, clinical, and therapeutic insights.

Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study.

Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study.

The role of oxidant stress in angiotensin II-mediated contraction of human resistance arteries in the state of health and the presence of cardiovascular disease.

Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells.

Proteomics and metabolomics combined in cardiovascular research.

Protein kinase D selectively targets cardiac troponin I and regulates myofilament Ca2+ sensitivity in ventricular myocytes.

Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study.

Integrated membrane protein analysis of mature and embryonic stem cell-derived smooth muscle cells using a novel combination of CyDye/biotin labeling.

Combined metabolomic and proteomic analysis of human atrial fibrillation.

The paradox of hypoxic and oxidative stress in atherosclerosis.

Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice.

Letter by Metzler et al regarding article, "Intracoronary KAI-9803 as an adjunct to primary coronary intervention for acute ST-segment elevation myocardial infarction".

Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study.

Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures.

Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.

Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population.

Proteomics of acute coronary syndromes.

Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures.

Identification of cardiac myosin-binding protein C as a candidate biomarker of myocardial infarction by proteomics analysis.

Endothelial progenitor cells, late stent thrombosis and delayed re-endothelialisation.

Proteomic analysis of the secretome of human umbilical vein endothelial cells using a combination of free-flow electrophoresis and nanoflow LC-MS/MS.

Phenotyping transgenic animals--an integrated readout of pathophysiology by combining proteomics and metabolomics with cardiovascular imaging.

Metabolomics: ready for the prime time?

Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.

Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution.

Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin.

Comparative proteomics profiling reveals role of smooth muscle progenitors in extracellular matrix production.

Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism.

Proteomics characterization of extracellular space components in the human aorta.

Coupling vascular and myocardial inflammatory injury into a common phenotype of cardiovascular dysfunction: systemic inflammation and aging - a mini-review.

Preoperative high-dose atorvastatin for prevention of atrial fibrillation after cardiac surgery: a randomized controlled trial.

Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes.

Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin.

Nitrosative protein oxidation is modulated during early endotoxemia.

Cardiovascular proteomics.

Proteomic analysis of secretory proteins and vesicles in vascular research.

Highlights from the 2010 BAS/BSCR spring meeting: New Frontiers in Cardiovascular Research.

Proteomic characterization of human early pro-angiogenic cells.

Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation.

Cardiovascular stem cells revisited.

Proteomics: a reality-check for putative stem cells.

Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome.

Comparative lipidomics profiling of human atherosclerotic plaques.

Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization.

Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach.

Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.

Chromobox protein homolog 3 is essential for stem cell differentiation to smooth muscles in vitro and in embryonic arteriogenesis.

Substrate modifications precede the development of atrial fibrillation after cardiac surgery: a proteomic study.

Recent highlights of metabolomics in cardiovascular research.

Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.

The -omics era: proteomics and lipidomics in vascular research.

Profiling of circulating microRNAs: from single biomarkers to re-wired networks.

Pathogenesis of varicose veins.

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

MicroRNAs in vascular and metabolic disease.

Method for protein subfractionation of cardiovascular tissues before DIGE analysis.

Review focus on the role of microRNA in cardiovascular biology and disease.

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.

Novel role of ADAMTS-5 protein in proteoglycan turnover and lipoprotein retention in atherosclerosis.

Analytical challenges and technical limitations in assessing circulating miRNAs.

Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes.

Prospective study on circulating MicroRNAs and risk of myocardial infarction.

Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions.

Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events.

Proteomics: from single molecules to biological pathways.

Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques.

Proteomic identification of matrix metalloproteinase substrates in the human vasculature.

Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome.

Circulating microRNAs as novel biomarkers for platelet activation.

MicroRNAs within the continuum of postgenomics biomarker discovery.

Glycoproteomic analysis of the secretome of human endothelial cells.

From data gathering to systems medicine.

Native T1 mapping in differentiation of normal myocardium from diffuse disease in hypertrophic and dilated cardiomyopathy.

Endothelial seeding for abdominal aortic aneurysms: lessons learned from the past and present.

A sequential extraction methodology for cardiac extracellular matrix prior to proteomics analysis.

Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.

Proteomics in aortic aneurysm--what have we learnt so far?

Oxidative stress in atherosclerosis: the role of microRNAs in arterial remodeling.

Impact of intravenous heparin on quantification of circulating microRNAs in patients with coronary artery disease.

MicroRNA biomarkers for failing hearts?

Vascular proteomics--the forgotten blood vessels.

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

Gestational diabetes mellitus impairs Nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero.

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.

Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2.

Multidimensional separation prior to mass spectrometry: getting closer to the bottom of the iceberg.

Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation.

Gene network and proteomic analyses of cardiac responses to pathological and physiological stress.

Phosphoregulation of the titin-cap protein telethonin in cardiac myocytes.

Effects of heparin on temporal microRNA profiles.

Signature of circulating microRNAs in osteoarthritis.

ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models.

Lipidomics profiling and risk of cardiovascular disease in the prospective population-based Bruneck study.

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.

Tracing the proteomic fingerprint of the diabetic aorta?

Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy.

Proteomics and metabolomics for mechanistic insights and biomarker discovery in cardiovascular disease.

Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis.

Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice.

Discrimination and net reclassification of cardiovascular risk with lipoprotein(a): prospective 15-year outcomes in the Bruneck Study.

Role of miR-195 in aortic aneurysmal disease.

LDL-receptor-deficient mice lacking microRNA-143/145 have less atherosclerosis.

"Going long": long non-coding RNAs as biomarkers.

Native T1 in discrimination of acute and convalescent stages in patients with clinical diagnosis of myocarditis: a proposed diagnostic algorithm using CMR.

Lipidomics: quest for molecular lipid biomarkers in cardiovascular disease.

Affinity proteomics for phosphatase interactions in atrial fibrillation.

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion.

ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1.

Functional Genomics of Cardioprotection by Ischemic Conditioning and the Influence of Comorbid Conditions: Implications in Target Identification.

Asymmetric dimethylarginine and cardiovascular risk: systematic review and meta-analysis of 22 prospective studies.

Novel methodologies for biomarker discovery in atherosclerosis.

Correlates of serum hepcidin levels and its association with cardiovascular disease in an elderly general population.

Sweet dicer: impairment of micro-RNA processing by diabetes.

Comparative analysis of statistical methods used for detecting differential expression in label-free mass spectrometry proteomics.

Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association.

Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart.

XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling.

Inadequate hepcidin serum concentrations predict incident type 2 diabetes mellitus.

Angiogenic microRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes.

MicroRNA Biomarkers for Coronary Artery Disease?

Association of MicroRNAs and YRNAs With Platelet Function.

Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside.

"Young at heart": Regenerative potential linked to immature cardiac phenotypes.

When Sweet Turns Salty: Glucose-Induced Suppression of Atrial Natriuretic Peptide by MicroRNA-425.

Guidelines for the functional annotation of microRNAs using the Gene Ontology.

Oxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2.

Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

Pharmacogenetics of Clopidogrel: An Unresolved Issue.

Liver microRNAs: potential mediators and biomarkers for metabolic and cardiovascular disease?

Chronic miR-29 antagonism promotes favorable plaque remodeling in atherosclerotic mice.

Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms.

Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase-1 in vascular endothelial growth factor-mediated angiogenesis.

Native T1 and T2 mapping by CMR in lupus myocarditis: Disease recognition and response to treatment.

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

Caveats of Untargeted Metabolomics for Biomarker Discovery.

Systems biology-opportunities and challenges: the application of proteomics to study the cardiovascular extracellular matrix.

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research".

Potential and Caveats of Lipidomics for Cardiovascular Disease.

Cardioprotection and lifespan extension by the natural polyamine spermidine.

Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes.

MicroRNAs in Cardiovascular Disease.

Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin.

High-density lipoproteins in high resolution: Will proteomics solve the paradox for cardiovascular risk?

Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium.

MicroRNA Biomarkers and Platelet Reactivity: The Clot Thickens.

Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III.

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.

Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation.