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Ke-lian Chen

Neurogenetics Branch,
National Institute of Neurological Disorders and Stroke,
Neurogenetics Branch, National Institute of Neurological Disorders and Stroke

National Institutes of Health

BIOGRAPHY

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PUBLICATIONS

Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy.

Molecular medicine (Cambridge, Mass.) Dec, 2012 | Pubmed ID: 22952056

Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients.

Neurobiology of disease Oct, 2014 | Pubmed ID: 24925468

Early onset and novel features in a spinal and bulbar muscular atrophy patient with a 68 CAG repeat.

Neuromuscular disorders : NMD Nov, 2014 | Pubmed ID: 25047668

Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia.

JAMA neurology May, 2015 | Pubmed ID: 25751282

MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy.

Molecular therapy : the journal of the American Society of Gene Therapy 05, 2016 | Pubmed ID: 26755334

A novel mutation in in a Malian family with spastic paraplegia and sensory loss.

Annals of clinical and translational neurology 04, 2017 | Pubmed ID: 28382308

INSTITUTIONS

National Institutes of Health

JOVE ARTICLES

Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents

Naemeh Pourshafie¹,

Philip R. Lee²,

Ke-lian Chen¹,

George G. Harmison¹,

Laura C. Bott^1,3,

Kenneth H. Fischbeck¹,

Carlo Rinaldi^1,4

¹Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health,

²Section on Nervous System Development and Plasticity, The Eunice Kennedy Shriver National Institute of Child and Human Development, National Institutes of Health,

³Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University,

⁴Department of Physiology, Anatomy and Genetics, University of Oxford

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Ke-lian Chen

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Neurogenetics Branch,National Institute of Neurological Disorders and Stroke,Neurogenetics Branch, National Institute of Neurological Disorders and Stroke

National Institutes of Health

Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents

Neurogenetics Branch,
National Institute of Neurological Disorders and Stroke,
Neurogenetics Branch, National Institute of Neurological Disorders and Stroke