Xiangjian Zheng
Lab of Cardiovascular Signaling
Centenary Institute
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AngII induces transient phospholipase D activity in the H295R glomerulosa cell model.
Molecular and cellular endocrinology Aug, 2003 | Pubmed ID: 12943994
Modulation of phospholipase D-mediated phosphatidylglycerol formation by differentiating agents in primary mouse epidermal keratinocytes.
Biochimica et biophysica acta Dec, 2003 | Pubmed ID: 14654225
Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation.
The Journal of investigative dermatology Dec, 2003 | Pubmed ID: 14675200
Phospholipase d signaling and extracellular signal-regulated kinase-1 and -2 phosphorylation (activation) are required for maximal phorbol ester-induced transglutaminase activity, a marker of keratinocyte differentiation.
The Journal of pharmacology and experimental therapeutics Mar, 2005 | Pubmed ID: 15537826
Enrichment of regulatory CD4(+)CD25(+) T cells by inhibition of phospholipase D signaling.
Nature methods Aug, 2006 | Pubmed ID: 16862138
A potential role for the phospholipase D2-aquaporin-3 signaling module in early keratinocyte differentiation: production of a phosphatidylglycerol signaling lipid.
The Journal of investigative dermatology Dec, 2007 | Pubmed ID: 17597824
Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.
Nature medicine Feb, 2009 | Pubmed ID: 19151727
Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish.
Developmental biology Apr, 2009 | Pubmed ID: 19389349
CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.
The Journal of clinical investigation Aug, 2010 | Pubmed ID: 20592472
Aquaporin-3 in keratinocytes and skin: its role and interaction with phospholipase D2.
Archives of biochemistry and biophysics Apr, 2011 | Pubmed ID: 21276418
Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth.
Developmental cell Aug, 2012 | Pubmed ID: 22898778
Cerebral cavernous malformations arise independent of the heart of glass receptor.
Stroke May, 2014 | Pubmed ID: 24643410
The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
Developmental cell Jan, 2015 | Pubmed ID: 25625206
Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.
Nature Apr, 2016 | Pubmed ID: 27027284
Corrigendum: Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.
Nature 08, 2016 | Pubmed ID: 27281211
Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice.
PloS one , 2016 | Pubmed ID: 27513872
A MicroRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability.
Circulation research Jan, 2017 | Pubmed ID: 27756792
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.
Nature 05, 2017 | Pubmed ID: 28489816
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