Lingna Li

High efficiency genetic modification of hair follicles and growing hair shafts.

Nestin expression in hair follicle sheath progenitor cells.

Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells.

Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells.

Real-time whole-body imaging of an orthotopic metastatic prostate cancer model expressing red fluorescent protein.

Transgenic nude mouse with ubiquitous green fluorescent protein expression as a host for human tumors.

Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited by Doxorubicin.

Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons.

Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis.

Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves.

Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine.

Chemotherapy targets the hair-follicle vascular network but not the stem cells.

Chemically programmed antibodies: endothelin receptor targeting CovX-Bodies.

Visualization of nascent tumor angiogenesis in lung and liver metastasis by differential dual-color fluorescence imaging in nestin-linked-GFP mice.

GFP-expressing vascularization of Gelfoam as a rapid in vivo assay of angiogenesis stimulators and inhibitors.

NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells.

Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function.

PML/RARalpha fusion protein mediates the unique sensitivity to arsenic cytotoxicity in acute promyelocytic leukemia cells: Mechanisms involve the impairment of cAMP signaling and the aberrant regulation of NADPH oxidase.

Multipotent nestin-expressing hair follicle stem cells.

Selective activity against proliferating tumor endothelial cells by CVX-22, a thrombospondin-1 mimetic CovX-Body.

Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-alpha-reductase inhibitor: a treatment strategy for acne.

Nestin-expressing interfollicular blood vessel network contributes to skin transplant survival and wound healing.

Embryonic development of hair follicle pluripotent stem (hfPS) cells.

Chemical generation of bispecific antibodies.

Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth.

Antitumor efficacy of a thrombospondin 1 mimetic CovX-body.