David A. Schofield

Development of a P1 phagemid system for the delivery of DNA into Gram-negative bacteria.

Tight regulation and modulation via a C1-regulated promoter in Escherichia coli and Pseudomonas aeruginosa.

Doc-mediated cell killing in Shigella flexneri using a C1/LacI controlled expression system.

Detection of Candida albicans mRNA from formalin-fixed, paraffin-embedded mouse tissues by nested reverse transcription-PCR.

Use of genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for treatment of bacterial infections.

Development of a thermally regulated broad-spectrum promoter system for use in pathogenic gram-positive species.

Hydrolytic gene expression during oroesophageal and gastric candidiasis in immunocompetent and immunodeficient gnotobiotic mice.

beta-defensin expression in immunocompetent and immunodeficient germ-free and Candida albicans-monoassociated mice.

Divergent chemokine, cytokine and beta-defensin responses to gastric candidiasis in immunocompetent C57BL/6 and BALB/c mice.

Susceptibility of germfree phagocyte oxidase- and nitric oxide synthase 2-deficient mice, defective in the production of reactive metabolites of both oxygen and nitrogen, to mucosal and systemic candidiasis of endogenous origin.

Differential Candida albicans lipase gene expression during alimentary tract colonization and infection.

Candida albicans-conditioned medium protects yeast cells from oxidative stress: a possible link between quorum sensing and oxidative stress resistance.

Development of a yeast biosensor-biocatalyst for the detection and biodegradation of the organophosphate paraoxon.

Susceptibility of gnotobiotic transgenic mice (Tgepsilon26) with combined deficiencies in natural killer cells and T cells to wild-type and hyphal signalling-defective mutants of Candida albicans.

Candida glabrata and Candida albicans; dissimilar tissue tropism and infectivity in a gnotobiotic model of mucosal candidiasis.

Diagnostic bioluminescent phage for detection of Yersinia pestis.

Laser Capture Microdissection of Candida albicans from Host Tissue.