Emmanuel Skordalakes

A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion.

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading.

Structure and function of the conserved core of histone deposition protein Asf1.

Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin.

Structural insights into RNA-dependent ring closure and ATPase activation by the Rho termination factor.

Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability.

Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding.

Function and structure of a prokaryotic formylglycine-generating enzyme.

Structure of the Tribolium castaneum telomerase catalytic subunit TERT.

Telomerase and the benefits of healthy living.

Telomerase structure paves the way for new cancer therapies.

Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation.

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation.

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA.

Cdc13 N-terminal dimerization, DNA binding, and telomere length regulation.

Insights into Cdc13 dependent telomere length regulation.

Neural and synaptic defects in slytherin, a zebrafish model for human congenital disorders of glycosylation.

Telomerase structure function.