Christer Hogstrand

Dietary Trivalent Chromium Exposure Up-Regulates Lipid Metabolism in Coral Trout: The Evidence From Transcriptome Analysis.

Influence of chloride and metals on silver bioavailability to Atlantic salmon (Salmo salar) and Rainbow trout (Oncorhynchus mykiss) yolk-sac fry.

Binding and movement of silver in the intestinal epithelium of a marine teleost fish, the European flounder (Platichthys flesus).

Application of genomics and proteomics for study of the integrated response to zinc exposure in a non-model fish species, the rainbow trout.

Internal redistribution of radiolabelled silver among tissues of rainbow trout (Oncorhynchus mykiss) and European eel (Anguilla anguilla): the influence of silver speciation.

Intestinal zinc uptake in freshwater rainbow trout: evidence for apical pathways associated with potassium efflux and modified by calcium.

Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes.

Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio).

Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells.

ZINC-mediated gene expression offers protection against H2O2-induced cytotoxicity.

A newly identified CpG oligodeoxynucleotide motif that stimulates rainbow trout (Oncorhynchus mykiss) immune cells to produce immunomodulatory factors.

Identification, cloning and characterization of a plasma membrane zinc efflux transporter, TrZnT-1, from fugu pufferfish (Takifugu rubripes).

Dietary phenolic antioxidants, caffeic acid and Trolox, protect rainbow trout gill cells from nitric oxide-induced apoptosis.

Regulation of branchial zinc uptake by 1alpha,25-(OH)(2)D(3) in rainbow trout and associated changes in expression of ZIP1 and ECaC.

Influence of culture conditions on metal-induced responses in a cultured rainbow trout gill epithelium.

Cortisol stimulates the zinc signaling pathway and expression of metallothioneins and ZnT1 in rainbow trout gill epithelial cells.

An in vitro method to assess toxicity of waterborne metals to fish.

Regulation of ZIP and ZnT zinc transporters in zebrafish gill: zinc repression of ZIP10 transcription by an intronic MRE cluster.

Natural arsenic contaminated diets perturb reproduction in fish.

Zinc-controlled gene expression by metal-regulatory transcription factor 1 (MTF1) in a model vertebrate, the zebrafish.

Differential uptake and oxidative stress response in zebrafish fed a single dose of the principal copper and zinc enriched sub-cellular fractions of Gammarus pulex.

Bioavailability of a natural lead-contaminated invertebrate diet to zebrafish.

Dynamic transcriptomic profiles of zebrafish gills in response to zinc depletion.

Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation.

Cerebral gene expression in response to single or combined gestational exposure to methylmercury and selenium through the maternal diet.

Differential tolerance of two Gammarus pulex populations transplanted from different metallogenic regions to a polymetal gradient.

Cerebral gene expression and neurobehavioural development after perinatal exposure to an environmentally relevant polybrominated diphenylether (BDE47).

Physiological response to a metal-contaminated invertebrate diet in zebrafish: importance of metal speciation and regulation of metal transport pathways.

The effect of metal pollution on the population genetic structure of brown trout (Salmo trutta L.) residing in the River Hayle, Cornwall, UK.

Picomolar concentrations of free zinc(II) ions regulate receptor protein-tyrosine phosphatase β activity.

Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7.

Copper and zinc detoxification in Gammarus pulex (L.).

Protein kinase CK2 opens the gate for zinc signaling.

Zinc hyperaccumulation in squirrelfish (Holocentrus adscenscionis) and its role in embryo viability.

A mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3).

Uptake epithelia behave in a cell-centric and not systems homeostatic manner in response to zinc depletion and supplementation.

Gill cell culture systems as models for aquatic environmental monitoring.

Cross-omics gene and protein expression profiling in juvenile female mice highlights disruption of calcium and zinc signalling in the brain following dietary exposure to CB-153, BDE-47, HBCD or TCDD.

Zinc ions modulate protein tyrosine phosphatase 1B activity.

A primary FIsh Gill Cell System (FIGCS) for environmental monitoring of river waters.

Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism.

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: evidence for passive and facilitated transport.

Environmental monitoring of urban streams using a primary fish gill cell culture system (FIGCS).

Effect and mechanism of waterborne prolonged Zn exposure influencing hepatic lipid metabolism in javelin goby Synechogobius hasta.

Endoplasmic reticulum stress and disturbed calcium homeostasis are involved in copper-induced alteration in hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco.

Procedures for the reconstruction, primary culture and experimental use of rainbow trout gill epithelia.

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration.

Expression of the zinc importer protein ZIP9/SLC39A9 in glioblastoma cells affects phosphorylation states of p53 and GSK-3β and causes increased cell migration.

The metal face of protein tyrosine phosphatase 1B.

Endoplasmic reticulum (ER) stress and cAMP/PKA pathway mediated Zn-induced hepatic lipolysis.

Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets.

Dietary zinc addition influenced zinc and lipid deposition in the fore- and mid-intestine of juvenile yellow catfish Pelteobagrus fulvidraco.

Differential cytolocation and functional assays of the two major human SLC30A8 (ZnT8) isoforms.

Parallel in vivo and in vitro transcriptomics analysis reveals calcium and zinc signalling in the brain as sensitive targets of HBCD neurotoxicity.

Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS).

The C-terminal cytosolic domain of the human zinc transporter ZnT8 and its diabetes risk variant.

Role of Zinc and Magnesium Ions in the Modulation of Phosphoryl Transfer in Protein Tyrosine Phosphatase 1B.

Impact of Various Factors on Color Stability of Fresh Blueberry Juice during Storage.

Prolonged stimulation of insulin release from MIN6 cells causes zinc depletion and loss of β-cell markers.

Zinc reduces hepatic lipid deposition and activates lipophagy via Zn/MTF-1/PPARα and Ca/CaMKKβ/AMPK pathways.

Low dose exposure to HBCD, CB-153 or TCDD induces histopathological and hormonal effects and changes in brain protein and gene expression in juvenile female BALB/c mice.

Biokinetic Modeling of Cd Bioaccumulation from Water, Diet and Sediment in a Marine Benthic Goby: A Triple Stable Isotope Tracing Technique.

Zn Stimulates the Phospholipids Biosynthesis via the Pathways of Oxidative and Endoplasmic Reticulum Stress in the Intestine of Freshwater Teleost Yellow Catfish.

Upstream regulators of apoptosis mediates methionine-induced changes of lipid metabolism.

SREBP1, PPARG and AMPK pathways mediated the Cu-induced change in intestinal lipogenesis and lipid transport of yellow catfish Pelteobagrus fulvidraco.

Machine Learning for Environmental Toxicology: A Call for Integration and Innovation.

Ecological Recovery and Resilience in Environmental Risk Assessments at the European Food Safety Authority.

The Use of Molecular Descriptors To Model Pharmaceutical Uptake by a Fish Primary Gill Cell Culture Epithelium.

Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ pathways.

ZnT8 Haploinsufficiency Impacts MIN6 Cell Zinc Content and β-Cell Phenotype via ZIP-ZnT8 Coregulation.

The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma.

FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity.

Creb-Pgc1α pathway modulates the interaction between lipid droplets and mitochondria and influences high fat diet-induced changes of lipid metabolism in the liver and isolated hepatocytes of yellow catfish.

The zebrafish Znt1a mutant reveals roles of zinc transporter-1a in embryonic development.

Hatching gland development and hatching in zebrafish embryos: A role for zinc and its transporters Zip10 and Znt1a.

The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis.

Waterborne copper exposure up-regulated lipid deposition through the methylation of GRP78 and PGC1α of grass carp Ctenopharyngodon idella.

Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.

Developing in vitro models to assess fish gill excretion of emerging contaminants.

Effect of Water pH on the Uptake of Acidic (Ibuprofen) and Basic (Propranolol) Drugs in a Fish Gill Cell Culture Model.

Zn Induces Lipophagy via the Deacetylation of Beclin1 and Alleviates Cu-Induced Lipotoxicity at Their Environmentally Relevant Concentrations.

Environmentally relevant concentrations of oxytetracycline and copper increased liver lipid deposition through inducing oxidative stress and mitochondria dysfunction in grass carp Ctenopharyngodon idella.

Effects of Low-Dose Gestational TCDD Exposure on Behavior and on Hippocampal Neuron Morphology and Gene Expression in Mice.

Estrogenicity of chemical mixtures revealed by a panel of bioassays.

Oxidized fish oils increased lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the CREB1-Bcl2-Beclin1 pathway in the liver tissues and hepatocytes of yellow catfish.

Waterborne zinc bioaccumulation influences glucose metabolism in orange-spotted grouper embryos.

Cultured rainbow trout gill epithelium as an method for marine ecosystem toxicological studies.

Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways.

Lipophagy mediated glucose-induced changes of lipid deposition and metabolism via ROS dependent AKT-Beclin1 activation.