Jason Dufour

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.

CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells.

Neurogenesis of Rhesus adipose stromal cells.

Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses.

Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

Expression of telomerase extends the lifespan and enhances osteogenic differentiation of adipose tissue-derived stromal cells.

Characterization of multipotent mesenchymal stem cells from the bone marrow of rhesus macaques.

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.

Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor.

Preclinical evaluation of adult stem cell engraftment and toxicity in the CNS of rhesus macaques.

Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.

Comparison of efficacy of moxidectin and ivermectin in the treatment of Strongyloides fulleborni infection in rhesus macaques.

Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue.

Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts.

Local and systemic effects of intranodally injected CpG-C immunostimulatory-oligodeoxyribonucleotides in macaques.

Virus-specific T cell responses in macaques acutely infected with SHIV(sf162p3).

Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain.

Complications of gastric catheters implanted in rhesus macaques (Macaca mulatta).

Simian immunodeficiency virus SIVagm dynamics in African green monkeys.

Differential cross-reactivity of monoclonal antibody OPD4 (anti-CD45RO) in macaques.

Long-term in vitro expansion alters the biology of adult mesenchymal stem cells.

Interaction of the Lyme disease spirochete Borrelia burgdorferi with brain parenchyma elicits inflammatory mediators from glial cells as well as glial and neuronal apoptosis.

Alcohol exposure impairs myeloid dendritic cell function in rhesus macaques.

Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host.

Detection of norovirus-, sapovirus- and rhesus enteric calicivirus-specific antibodies in captive juvenile macaques.

Visualization of transepithelial passage of the immunogenic 33-residue peptide from alpha-2 gliadin in gluten-sensitive macaques.

Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication.

Cell-dose-dependent increases in circulating levels of immune effector cells in rhesus macaques following intracranial injection of allogeneic MSCs.

Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.

Simian immunodeficiency virus selectively infects proliferating CD4+ T cells in neonatal rhesus macaques.

Vesicular stomatitis virus-simian retrovirus type 2 vaccine protects macaques from detectable infection and B-cell destruction.

Disrupted anabolic and catabolic processes may contribute to alcohol-accentuated SAIDS-associated wasting.