Ken Takahashi
Department of Cardiovascular Physiology,
Graduate School of Medicine,
Dentistry and Pharmaceutical Sciences,
Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Okayama University
Ken is currently a Research Associate Professor at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences in Japan. He directs research groups focused on organ-on-a-chip, ischemia-reperfusion injury, cardiovascular regenerative medicine, and space medicine/biology.
As a visiting scholar in Wyss Institute for Biologically Inspired Engineering at Harvard Medical School, he developed a model of ischemia-reperfusion injury using the organ-on-a-chip technology. His interests also extend to physics simulation including finite element analysis and molecular dynamics.
Ken received his Ph.D. in Medicine from Nagoya University. He is a member of the Cellular Biology of the Heart Working Group in European Society of Cardiology, and a councilor of the Physiological Society of Japan. He serves on the Editorial Boards of journals including AIMS Biophysics, Mechanobiology, Hearts, and Biology and Medicine.
He received several awards such as Award for Outstanding Research Achievement and Award for Outstanding Contribution to Education. Ken is running a joint research about space medicine with PD AeroSpace, Ltd. He is a finisher of an Ironman Triathlon race.
Stretch-activated BK channel and heart function.
Progress in biophysics and molecular biology Oct-Nov, 2012 | Pubmed ID: 23281538
Mechanobiology in cardiac physiology and diseases.
Journal of cellular and molecular medicine Feb, 2013 | Pubmed ID: 23441631
9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury.
PloS one , 2013 | Pubmed ID: 23936231
Transient receptor potential melastatin-4 is involved in hypoxia-reoxygenation injury in the cardiomyocytes.
PloS one , 2015 | Pubmed ID: 25836769
Mechanical Stretch on Human Skin Equivalents Increases the Epidermal Thickness and Develops the Basement Membrane.
PloS one , 2015 | Pubmed ID: 26528823
[Response to mechanical stimulus and cardiovascular homeostasis.]
Clinical calcium , 2016 | Pubmed ID: 27885177
TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca concentration in mouse cardiomyocytes.
The journal of physiological sciences : JPS Mar, 2018 | Pubmed ID: 28105583
Effect of Oxidative Stress on Cardiovascular System in Response to Gravity.
International journal of molecular sciences Jul, 2017 | Pubmed ID: 28677649
Role of the TRPM4 Channel in Cardiovascular Physiology and Pathophysiology.
Cells Jun, 2018 | Pubmed ID: 29914130
Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes.
Biochemical and biophysical research communications 09, 2018 | Pubmed ID: 30060947
L-type calcium channel modulates mechanosensitivity of the cardiomyocyte cell line H9c2.
Cell calcium 05, 2019 | Pubmed ID: 30836292
Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1.
Experimental cell research Oct, 2019 | Pubmed ID: 31415758
Development of a model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells.
Biochemical and biophysical research communications Dec, 2019 | Pubmed ID: 31623826
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